Biography

Wenxin Zheng, M.D., Tenured Professor of Pathology, Obstetrics and Gynecology, American board certified pathologist, graduated from Shanghai Medical College Fudan University and trained at Columbia University, Cornell University, and Brown University Medical Centers in anatomic pathology and gynecologic pathology, Selected by US News and World Report multiple times as one of America's top pathologists, Dr. Zheng is an internationally recognized gynecologic pathologist with outstanding expertise in every aspect of gynecologic pathology.  Dr. Zheng’s main research contributions include endometrial serous carcinogenesis and precancerous lesion endometrial glandular dysplasia, cell origin of low-grade ovarian serous carcinoma, hormonal etiology of ovarian epithelial cancers, and tubal contribution of ovarian endometriosis and its associated ovarian cancers.  In addition to these, Dr. Zheng has created a novel approach called "One Stop Cervical Care (OSCC)" to diagnose and treat cervical precancers. 

Education

Medical School
Shanghai Medical College of Fudan University (1982)
Internship
Hospital of Obstetrics and Gynecology (1983), Obstetrics & Gynecology
Residency
Hospital of Obstetrics and Gynecology (1986), Obstetrics & Gynecology
Fellowship
Columbia University Medical Center (1989), Molecular Reproduction
Residency
Cornell New York Presbyterian Hospital (1995), Pathology
Fellowship
Brown University Woman & Infant Hospital (1996), Gynecologic Pathology

Research Interest

  • Biomarkers to aid the diagnosis of gynecologic cancers
  • Cervical cancer: suitable model of cervical cancer screening, effective intervention, and prevention in developing countries.
  • Endometrial serous carcinoma: carcinogenesis, early detection and prevention
  • Ovarian cancer early detection and prevention
  • Tubal origin of ovarian endometriosis and its related cancer development
  • Tubal secretory cell biology

Publications

Featured Publications LegendFeatured Publications

Age cutoff for reporting of benign-appearing endometrial cells in Papanicolaou specimens; should it be raised? A 10-year retrospective study from a large county hospital.
Hinson S, Molberg K, Mir M, Flores M, Zheng W, Lucas E, J Am Soc Cytopathol 2019 Mar - Apr 8 2 78-83
Extended HPV genotyping and its application in cervical cancer screening
Yiying Wang, Yue Wang, Beihua Kong, Wenxin Zheng Advances of Modern Obstetrics and Gynecology 2019 28 79-81
Human Papillomavirus Genotyping in 1,088 Anal Cancer Precursor Cases: Expected and Unexpected Results
Yuxin Liu, Keith Sigel, Melissa Gitman, Tamara Kalir, William Westra, Wenxin Zheng, Michael M Gaisa AIDS 2019
Clinical significance of HPV genotyping and viral load in cervical cancer screening
Yue Wang, Yiying Wang, Xin Xie, Wenxin Zheng, Beihua Kong Chinese Journal of Obstetrics and Gynecology 2019 54 350-353
Aberrant expression of oxidative stress related proteins affects the pregnancy outcome of gestational diabetes mellitus patients.
Zhang C, Yang Y, Chen R, Wei Y, Feng Y, Zheng W, Liao H, Zhang Z Am J Transl Res 2019 11 1 269-279
Targeted Molecular and Immunohistochemical Analyses of Endometrial Clear Cell Carcinoma Show that POLE Mutations and DNA Mismatch Repair Protein Deficiencies are Uncommon.
Baniak N, Fadare O, Köbel M, DeCoteau J, Parkash V, Hecht JL, Hanley KZ, Gwin K, Zheng W, Quick CM, Jarboe EA, Liang SX, Kinloch M Am. J. Surg. Pathol. 2018 Dec
Estrogen affects the negative feedback loop of PTENP1-miR200c to inhibit PTEN expression in the development of endometrioid endometrial carcinoma.
Chen R, Zhang M, Liu W, Chen H, Cai T, Xiong H, Sheng X, Liu S, Peng J, Wang F, Chen H, Lin W, Xu X, Zheng W, Jiang Q Cell Death Dis 2018 Dec 10 1 4
Mismatch Repair Protein Expression in Endometrioid Intraepithelial Neoplasia/Atypical Hyperplasia: Should We Screen for Lynch Syndrome in Precancerous Lesions?
Lucas E, Chen H, Molberg K, Castrillon DH, Rivera Colon G, Li L, Hinson S, Thibodeaux J, Lea J, Miller DS, Zheng W Int. J. Gynecol. Pathol. 2018 Oct
Superficially invasive cervical squamous cell carcinoma metastatic to ovarian endometriotic cyst wall, a case report and brief review of the literature.
Zhang M, Lucas E, Xiong H, Liu S, Molberg K, Jiang Q, Zheng W J Ovarian Res 2018 May 11 1 44
Combination of TP53 and AGR3 to distinguish ovarian high-grade serous carcinoma from low-grade serous carcinoma.
Qiu C, Wang Y, Wang X, Zhang Q, Li Y, Xu Y, Jin C, Bu H, Zheng W, Yang X, Lu N, Kong B Int. J. Oncol. 2018 Apr

Books

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