Biography

Wenxin Zheng, M.D., Tenured Professor of Pathology, Obstetrics and Gynecology, American board certified pathologist, graduated from Shanghai Medical College Fudan University and trained at Columbia University, Cornell University, and Brown University Medical Centers in anatomic pathology and gynecologic pathology, Selected by US News and World Report multiple times as one of America's top pathologists, Dr. Zheng is an internationally recognized gynecologic pathologist with outstanding expertise in every aspect of gynecologic pathology.  Dr. Zheng’s main research contributions include endometrial serous carcinogenesis and precancerous lesion endometrial glandular dysplasia, cell origin of low-grade ovarian serous carcinoma, hormonal etiology of ovarian epithelial cancers, and tubal contribution of ovarian endometriosis and its associated ovarian cancers.  In addition to these, Dr. Zheng has created a novel approach called "One Stop Cervical Care (OSCC)" to diagnose and treat cervical precancers. 

Education

Medical School
Shanghai Medical College of Fudan University (1982)
Internship
Hospital of Obstetrics and Gynecology (1983), Obstetrics & Gynecology
Residency
Hospital of Obstetrics and Gynecology (1986), Obstetrics & Gynecology
Fellowship
Columbia University Medical Center (1989), Molecular Reproduction
Residency
Cornell New York Presbyterian Hospital (1995), Pathology
Fellowship
Brown University Woman & Infant Hospital (1996), Gynecologic Pathology

Research Interest

  • Biomarkers to aid the diagnosis of gynecologic cancers
  • Cervical cancer: suitable model of cervical cancer screening, effective intervention, and prevention in developing countries.
  • Endometrial serous carcinoma: carcinogenesis, early detection and prevention
  • Ovarian cancer early detection and prevention
  • Tubal origin of ovarian endometriosis and its related cancer development
  • Tubal secretory cell biology

Publications

Featured Publications LegendFeatured Publications

Serial genomic analysis of endometrium supports the existence of histologically indistinct endometrial cancer precursors.
Aguilar M, Zhang H, Zhang M, Cantarell B, Sahoo SS, Li HD, Cuevas IC, Lea J, Miller DS, Chen H, Zheng W, Gagan J, Lucas E, Castrillon DH, J Pathol 2021 Jan
PD-L1 Expression in Endocervical Adenocarcinoma: Correlation With Patterns of Tumor Invasion, CD8+ Tumor-infiltrating Lymphocytes, and Clinical Outcomes.
Rivera-Colon G, Chen H, Molberg K, Niu S, Strickland AL, Castrillon DH, Carrick K, Gwin K, Lea J, Zheng W, Lucas E, Am J Surg Pathol 2020 Dec
PD-L1 Expression and CD8+ Tumor-infiltrating Lymphocytes in Different Types of Tubo-Ovarian Carcinoma and Their Prognostic Value in High-grade Serous Carcinoma.
Chen H, Molberg K, Strickland AL, Castrillon DH, Carrick K, Jiang Q, Niu S, Rivera-Colon G, Gwin K, Hinson S, Lea J, Miller DS, Zheng W, Lucas E, Am. J. Surg. Pathol. 2020 May
Roles of follicle stimulating hormone and its receptor in human metabolic diseases and cancer.
Sun D, Bai M, Jiang Y, Hu M, Wu S, Zheng W, Zhang Z, Am J Transl Res 2020 12 7 3116-3132
Stigmasterol sensitizes endometrial cancer cells to chemotherapy by repressing Nrf2 signal pathway.
Liao H, Zhu D, Bai M, Chen H, Yan S, Yu J, Zhu H, Zheng W, Fan G, Cancer Cell Int 2020 20 480
Dedifferentiated Endometrioid Carcinomas with Neuroendocrine Differentiation: A Clinicopathological and Immunohistochemical Study of Three Cases.
Zhou F, Zhang X, Chen H, Zheng W, Cancer Manag Res 2020 12 11623-11629
Randomized Trial of Intravenous Versus Intraperitoneal Chemotherapy Plus Bevacizumab in Advanced Ovarian Carcinoma: An NRG Oncology/Gynecologic Oncology Group Study.
Walker JL, Brady MF, Wenzel L, Fleming GF, Huang HQ, DiSilvestro PA, Fujiwara K, Alberts DS, Zheng W, Tewari KS, Cohn DE, Powell MA, Van Le L, Davidson SA, Gray HJ, Rose PG, Aghajanian C, Myers T, Alvarez Secord A, Rubin SC, Mannel RS, J. Clin. Oncol. 2019 Jun 37 16 1380-1390
Challenges in the Pap diagnosis of endocervical adenocarcinoma in situ.
Niu S, Molberg K, Thibodeaux J, Rivera-Colon G, Hinson S, Zheng W, Lucas E, J Am Soc Cytopathol 2019 May - Jun 8 3 141-148

Books

Featured Books Legend Featured Books