Wenxin Zheng, M.D.
Professor

Wenxin Zheng, M.D., Tenured Professor of Pathology, Obstetrics and Gynecology, American board certified pathologist, graduated from Shanghai Medical College Fudan University and trained at Columbia University, Cornell University, and Brown University Medical Centers in anatomic pathology and gynecologic pathology, Selected by US News and World Report in 2013 as one of America's top pathologists, Dr. Zheng is an internationally recognized gynecologic pathologist with outstanding expertise in every aspect of gynecologic pathology.  Dr. Zheng’s main research contributions include endometrial serous carcinogenesis and precancerous lesion endometrial glandular dysplasia, cell origin of low-grade ovarian serous carcinoma, hormonal etiology of ovarian epithelial cancers, and tubal contribution of ovarian endometriosis and its associated ovarian cancers.  In addition to these, Dr. Zheng has created a novel approach called "One Stop Cervical Care (OSCC)" to diagnose and treat cervical precancers. 

Medical School

Shanghai Medical College of Fudan University (1982)

Internship

Hospital of Obstetrics and Gynecology (1983), Obstetrics & Gynecology

Residency

Hospital of Obstetrics and Gynecology (1986), Obstetrics & Gynecology

Fellowship

Columbia University Medical Center (1989), Molecular Reproduction

Residency

Cornell New York Presbyterian Hospital (1995), Pathology

Fellowship

Brown University Woman & Infant Hospital (1996), Gynecologic Pathology

• Biomarkers to aid the diagnosis of gynecologic cancers
• Cervical cancer: suitable model of cervical cancer screening, effective intervention, and prevention in developing countries.
• Endometrial serous carcinoma: carcinogenesis, early detection and prevention
• Ovarian cancer early detection and prevention
• Tubal origin of ovarian endometriosis and its related cancer development
• Tubal secretory cell biology

Featured Publications

Randomized Trial of Intravenous Versus Intraperitoneal Chemotherapy Plus Bevacizumab in Advanced Ovarian Carcinoma: An NRG Oncology/Gynecologic Oncology Group Study.

Walker JL, Brady MF, Wenzel L, Fleming GF, Huang HQ, DiSilvestro PA, Fujiwara K, Alberts DS, Zheng W, Tewari KS, Cohn DE, Powell MA, Van Le L, Davidson SA, Gray HJ, Rose PG, Aghajanian C, Myers T, Alvarez Secord A, Rubin SC, Mannel RS, J. Clin. Oncol. 2019 Jun 37 16 1380-1390

Challenges in the Pap diagnosis of endocervical adenocarcinoma in situ.

Niu S, Molberg K, Thibodeaux J, Rivera-Colon G, Hinson S, Zheng W, Lucas E, J Am Soc Cytopathol 2019 May - Jun 8 3 141-148

Metformin sensitizes endometrial cancer cells to progestin by targeting TET1 to downregulate glyoxalase I expression.

Jiang Y, Chen X, Wei Y, Feng Y, Zheng W, Zhang Z, Biomed. Pharmacother. 2019 May 113 108712

Effect of Progestin Usage on the Interpretation of Cervical High-grade Squamous Intraepithelial Lesion.

Wang Y, Chen H, Jiang Q, Luo R, Zhou P, Wang Y, Zhao R, Fadare O, Zheng W, Am. J. Surg. Pathol. 2019 Apr

Age cutoff for reporting of benign-appearing endometrial cells in Papanicolaou specimens; should it be raised? A 10-year retrospective study from a large county hospital.

Hinson S, Molberg K, Mir M, Flores M, Zheng W, Lucas E, J Am Soc Cytopathol 2019 Mar - Apr 8 2 78-83

Extended HPV genotyping and its application in cervical cancer screening

Yiying Wang, Yue Wang, Beihua Kong, Wenxin Zheng Advances of Modern Obstetrics and Gynecology 2019 28 79-81

Human Papillomavirus Genotyping in 1,088 Anal Cancer Precursor Cases: Expected and Unexpected Results

Yuxin Liu, Keith Sigel, Melissa Gitman, Tamara Kalir, William Westra, Wenxin Zheng, Michael M Gaisa AIDS 2019

Clinical significance of HPV genotyping and viral load in cervical cancer screening

Yue Wang, Yiying Wang, Xin Xie, Wenxin Zheng, Beihua Kong Chinese Journal of Obstetrics and Gynecology 2019 54 350-353

Tubal Origin of "Ovarian" Low-Grade Serous Carcinoma: A Gene Expression Profile Study.

Wang Y, Hong S, Mu J, Wang Y, Lea J, Kong B, Zheng W, J Oncol 2019 2019 8659754

Aberrant expression of oxidative stress related proteins affects the pregnancy outcome of gestational diabetes mellitus patients.

Zhang C, Yang Y, Chen R, Wei Y, Feng Y, Zheng W, Liao H, Zhang Z Am J Transl Res 2019 11 1 269-279

 Featured Books

Many chapters as leading or co-authors. In Gynecologic and Obstetrics Pathology

Wenxin Zheng et al., (Ed.) (2013). Beijing,China, Science Press

Endometrial Carcinogenesis. In Gynecologic and Obstetric Pathology, Volume 1

Wenxin Zheng Oluwole Fadare Charles Matthew Quick Danhua Shen Donghui Guo (Ed.) (2019). Singapore, Springer

Germ Cell Tumors and Mixed Germ Cell-Sex Cord-Stromal Tumors of the Ovary. In Gynecologic and Obstetric Pathology, Volume 2

Wenxin Zheng Oluwole Fadare Charles Matthew Quick Danhua Shen Donghui Guo (Ed.) (2019). Singapore, Springer