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Trung Nguyen, M.D.,  Ph.D.

Trung Nguyen, M.D., Ph.D.

Titles and Appointments

Associate Professor

School
Medical School
Department
Neurology

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For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    Joined UT Southwestern: 2016

    Clinical Interests: Trung P. Nguyen, M.D., Ph.D. specializes in disorders of cognition and dementias such as Alzheimer’s disease and dementia with Lewy bodies.

    Research: Dr. Nguyen’s research focus is on neurodegenerative diseases and dementias. He is actively involved in observational and interventional clinical trials for Alzheimer’s disease.  He has also received research funding from the Texas Alzheimer’s Research and Care Consortium and the National Institute on Aging to investigate the pathologic mechanisms underlying Alzheimer’s disease and dementia with Lewy bodies.

    Background: Dr. Nguyen earned his M.D. and Ph.D. in neuroscience from the University of Texas Medical Branch at Galveston.  He then completed his residency in neurology at Emory University in Atlanta, GA.  He returned to Texas to complete his fellowship in behavioral neurology and neuropsychiatry at UT Southwestern Medical Center, and subsequently accepted a faculty position here.

  • Education
    Other Post Graduate Training
    The University of Texas Medical Branch at Galveston (2010)
    Medical School
    UT Medical Branch at Galveston (2010)
    Internship
    Emory University School of Medicine (2011), Internal Medicine
    Residency
    Emory University School of Medicine (2014), Neurology
    Fellowship
    UT Southwestern Medical Center (2016), Behavioral Neurology & Dementia
  • Research Interest
    • Alzheimer's disease
    • Dementia with Lewy bodies
    • Neurodegenerative diseases
  • Publications
    High definition transcranial direct current stimulation as an intervention for cognitive deficits in Alzheimer's dementia: A randomized controlled trial
    LoBue C, Chiang H, Salter A, McClintock S, Nguyen TP, Logan R, Smernoff EN, Pandya S, Hart J The journal of prevention of Alzheimer's disease 2025 Feb 12 100023
    The Clinical Value of NeuroQuant Hippocampal Volumes and Hippocampal Occupancy Scores in an Academic Medical Center Memory Clinic
    Schaffert J, Goette W, Nguyen TP, Khera A, Ruchinskas R Cognitive and Behavioral Neurology 2025
    Prognostic relevance of gait-related cognitive functions for dementia conversion in amnestic mild cognitive impairment
    Author Collaboration TA, Tuena C, Maestri S, Serino S, Pedroli E, Stramba-Badiale M, Riva G, Silbert LC, Lind B, Crissey R, Kaye JA, Carter R, Dolen S, Quinn J, Schneider LS, Pawluczyk S, Becerra M, Teodoro L, Dagerman K, Spann BM, Brewer J, Fleisher A, Vanderswag H, Ziolkowski J, Heidebrink JL, Zbizek-Nulph L, Lord JL, Albers CS, Petersen R, Mason SS, Knopman D, Johnson K, Villanueva-Meyer J, Pavlik V, Pacini N, Lamb A, Kass JS, Doody RS, Shibley V, Chowdhury M, Rountree S, Dang M, Stern Y, Honig LS, Mintz A, Kelley B, Nguyen T, Mathews D, Quiceno M, Hajjar I, Kerwin D BMC Geriatrics 2023 Dec 23
    Identifying healthy individuals with Alzheimer’s disease neuroimaging phenotypes in the UK Biobank
    Author Collaboration TA, Azevedo T, Bethlehem RA, Whiteside DJ, Swaddiwudhipong N, Rowe JB, Lió P, Rittman T, Li G, Petrie EC, Peskind ER, Villena T, Martinez W, Sadowsky C, Lee A, Ravdin L, Lin M, Chiang G, Relkin N, Santulli RB, Hynes ML, Seltzer M, Flashman LA, Anderson K, Blank K, Pearlson GD, Kittur S, Correia S, Malloy P, Salloway S, Potkin S, Newhouse P, Garcia A, Shi J, Masdeu J, Wiliams A, Mintzer J, O’Connelll A, Mintz A, Munic D, Bernick C, Ritter A, Drake JD, Daiello LA, Tremont G, Drake J, Ott BR, Kerwin D, Hajjar I, Quiceno M, Nguyen T Communications Medicine 2023 Dec 3
    HBS-1.2: Lightweight Socially Assistive Robot with 6-Ply Twisted Coiled Polymer Muscle-Actuated Hand
    Singh AP, Palani D, Ahmed O, Matharu PS, Linn T, Nguyen T, Tadesse Y Actuators 2023 Aug 12
    Regional Neuroanatomic Effects on Brain Age Inferred Using Magnetic Resonance Imaging and Ridge Regression
    Author Collaboration AD, Massett RJ, Maher AS, Imms PE, Amgalan A, Chaudhari NN, Chowdhury NF, Irimia A, Weiner MW, Aisen P, Petersen R, Jack CR, Jagust W, Trojanowki JQ, Toga AW, Beckett L, Green RC, Saykin AJ, Morris JC, Perrin RJ, Shaw LM, Khachaturian Z, Carrillo M, Potter W, Barnes L, Bernard M, González H, Ho C, Hsiao JK, Jackson J, Masliah E, Masterman D, Okonkwo O, Ryan L, Silverberg N, Fleisher A, Sacrey DT, Fockler J, Conti C, Veitch D, Neuhaus J, Jin C, Nosheny R, Ashford M, Householder E, Kelley B, Nguyen T, Womack KB, Quiceno M, Hajjar I, Kerwin D Journals of Gerontology - Series A Biological Sciences and Medical Sciences 2023 Jun 78 872-881
    A predictive model using the mesoscopic architecture of the living brain to detect Alzheimer’s disease
    Author Collaboration TA, Inglese M, Patel N, Linton-Reid K, Loreto F, Win Z, Perry RJ, Carswell C, Grech-Sollars M, Crum WR, Lu H, Malhotra PA, Silbert LC, Lind B, Crissey R, Kaye JA, Carter R, Dolen S, Quinn J, Schneider LS, Pawluczyk S, Becerra M, Teodoro L, Dagerman K, Spann BM, Brewer J, Vanderswag H, Fleisher A, Ziolkowski J, Heidebrink JL, Lord JL, Zbizek-Nulph L, Petersen R, Mason SS, Albers CS, Knopman D, Johnson K, Villanueva-Meyer J, Pavlik V, Pacini N, Lamb A, Kass JS, Doody RS, Shibley V, Rountree S, Nguyen T, Quiceno M, Hajjar I, Kerwin D, Kelley B Communications Medicine 2022 Dec 2
    The Polygenic Risk Score Knowledge Base offers a centralized online repository for calculating and contextualizing polygenic risk scores
    Author Collaboration TA, Author Collaboration CU, Author Collaboration DM, Author Collaboration HH, Author Collaboration NC, Author Collaboration BH, Author Collaboration LB, Author Collaboration VU, Author Collaboration BN, Author Collaboration HM, Author Collaboration RS, Author Collaboration CC, Author Collaboration RI, Author Collaboration WF, Author Collaboration Uo, Author Collaboration AM, Author Collaboration OS, Author Collaboration BA, Author Collaboration Uo, Author Collaboration PI, Author Collaboration DN, Author Collaboration Uo, Author Collaboration CW, Author Collaboration HU, Author Collaboration BU, Author Collaboration BS, Author Collaboration SU, Author Collaboration Ba, Author Collaboration GU, Author Collaboration Uo, Author Collaboration NK, Author Collaboration NU, Author Collaboration SJ, Author Collaboration Uo, Author Collaboration SH, Author Collaboration MU, Author Collaboration YU, Author Collaboration IU, Author Collaboration MC, Author Collaboration Uo, Author Collaboration Uo, Author Collaboration EU, Author Collaboration Uo, Author Collaboration Uo, Author Collaboration Uo, Author Collaboration Uo, Author Collaboration Uo, Author Collaboration Uo, Author Collaboration DU, Author Collaboration NY, Author Collaboration Uo, Author Collaboration JH, Author Collaboration WC, Author Collaboration RU, Author Collaboration MS, Author Collaboration Uo, Author Collaboration WU, Author Collaboration CU, Author Collaboration BC, Author Collaboration MC, Author Collaboration Uo, Author Collaboration Uo, Author Collaboration Uo, Author Collaboration OH, Author Collaboration NI, Author Collaboration IC, Author Collaboration GC, Author Collaboration IC, Author Collaboration BC, Author Collaboration NC, Author Collaboration PC, Author Collaboration MC, Author Collaboration BC, Author Collaboration CC, Author Collaboration RA, Author Collaboration Da, Author Collaboration AC, Author Collaboration A3, Author Collaboration AE, Author Collaboration EC, Author Collaboration AP, Author Collaboration PI, Page ML, Vance EL, Cloward ME, Ringger E, Dayton L, Ebbert MT, Ravdin L, Lin M, Lee A, Chiang G, Relkin N, Santulli RB, Hynes ML, Seltzer M, Flashman LA, Anderson K, Blank K, Perlson GD, Kittur S, Correia S, Malloy P, Salloway S, Potkin S, Newhouse P, Sabbagh M, Garcia A, Shi J, Masdeu J, Williams A, Mintzer J, O’Connell A, Mintz A, Munic D, Bernick C, Ritter A, Daiello LA, Tremont G, Drake JD, Ott BR, Sink KM, Yang M, Cleveland J, Craft S, Williamson JD, Schultz SK, Ponto LL, Kerwin D, Hajjar I, Quiceno M, Nguyen T Communications Biology 2022 Dec 5
    A combined polygenic score of 21,293 rare and 22 common variants improves diabetes diagnosis based on hemoglobin A1C levels
    Author Collaboration AC, Dornbos P, Koesterer R, Ruttenburg A, Nguyen T, Cole JB, Leong A, Meigs JB, Florez JC, Rotter JI, Udler MS, Flannick J Nature genetics 2022 Nov 54 1609-1614
    Cognitive Decline in Older People with Multiple Sclerosis—A Narrative Review of the Literature
    Chiang H, Khera A, Stopschinski BE, Stuve O, Hart J, Kelley B, Nguyen T Geriatrics (Switzerland) 2022 Jun 7
  • Professional Associations/Affiliations
    • American Academy of Neurology (2011)