Douglas Strand, Ph.D.
Assistant Professor

Download Curriculum Vitae

Dr. Strand completed his PhD in the laboratory of David Rowley, PhD in the department of Molecular and Cellular Biology at Baylor College of Medicine. There he worked on the molecular mechanisms regulating reactive stroma in prostate cancer. From there Dr. Strand moved on to the laboratory of Simon Hayward, PhD in the Urology department at Vanderbilt University to perform his post-doctoral training. It was here that Dr. Strand developed an interest in solving the cellular and molecular pathogenesis of benign prostatic hyperplasia. In 2014, Dr. Strand joined forces with Claus Roehrborn, MD, chair of the Urology department at UT Southwestern and a world-renowned expert in BPH treatment. Dr. Strand has developed an unparalleled human tissue biorepository that is used for his translational research program and is actively pursuing molecular targets for the development of novel medical treatments for this widespread disease.

Undergraduate

Liberty University (2001), Biology

Graduate School

Baylor College of Medicine (2007), Molecular & Cell Biology

• Benign Prostatic Hyperplasia
• Prostate Cancer

Featured Publications

OMIP-040: Optimized gating of human prostate cellular subpopulations.

Henry GH, Loof N, Strand DW Cytometry A 2017 Aug

Targeting phenotypic heterogeneity in benign prostatic hyperplasia.

Strand DW, Costa DN, Francis F, Ricke WA, Roehrborn CG Differentiation 2017 Aug 96 49-61

Molecular pathogenesis of human prostate basal cell hyperplasia.

Henry G, Malewska A, Mauck R, Gahan J, Hutchinson R, Torrealba J, Francis F, Roehrborn C, Strand D Prostate 2017 Aug

Surgical intervention for symptomatic benign prostatic hyperplasia is correlated with expression of the AP-1 transcription factor network.

Lin-Tsai O, Clark PE, Miller NL, Fowke JH, Hameed O, Hayward SW, Strand DW Prostate 2014 May 74 6 669-79

Perspectives on tissue interactions in development and disease.

Strand DW, Franco OE, Basanta D, Anderson AR, Hayward SW Curr. Mol. Med. 2010 Feb 10 1 95-112

Deficiency in metabolic regulators PPAR? and PTEN cooperates to drive keratinizing squamous metaplasia in novel models of human tissue regeneration.

Strand DW, DeGraff DJ, Jiang M, Sameni M, Franco OE, Love HD, Hayward WJ, Lin-Tsai O, Wang AY, Cates JM, Sloane BF, Matusik RJ, Hayward SW Am. J. Pathol. 2013 Feb 182 2 449-59

PPAR? isoforms differentially regulate metabolic networks to mediate mouse prostatic epithelial differentiation.

Strand DW, Jiang M, Murphy TA, Yi Y, Konvinse KC, Franco OE, Wang Y, Young JD, Hayward SW Cell Death Dis 2012 3 e361

PPAR?: a molecular link between systemic metabolic disease and benign prostate hyperplasia.

Jiang M, Strand DW, Franco OE, Clark PE, Hayward SW Differentiation 2011 Nov-Dec 82 4-5 220-36

• AUA Travel Award
  (2013)
• K01DK098277
  Mentored training grant on the role of metabolism in prostate differentiation and disease (2013-2018)
• StarBrite VICTR award
  Pilot funding to study the role of inflammation in BPH progression (2013-2014)
• SBUR Travel award and podium presentation
  (2012)
• NIH LRP award
  Loan repayment program award (2010-2012)
• StarBrite VICTR award
  Pilot funding to study the role of lipid metabolism in prostate cancer (2010-2011)
• DoD Postdoctoral Training Award
  2 year fellowship to study the role of stomal-epithelial interactions in prostate cancer progression (2009-2011)
• SBUR travel award
  (2006)

• American Urological Association (2014)
• Society for Basic Urologic Research (2009)