Kathryn Dickerson, M.D.

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Kathryn E. Dickerson, M.D., M.S.C.S is an Assistant Professor in the Department of Pediatrics, Division of Hematology and Oncology, and 2015 Translational Research Scholar in the UTSW Center for Translational Medicine.

She earned her undergraduate degree in Biochemistry with a minor in Spanish from Indiana University. Before attending medical school, she completed a post-baccalaureate research training program at the NIH working in the laboratory of Dr. Lee Weinstein. She returned to Indiana University to earn her medical degree, working in the laboratory of Dr. Nadia Carlesso. She completed her pediatric residency training in an integrated research pathway at The Ohio State University/Nationwide Children's Hospital, working in the laboratory of Dr. Michael Caligiuri. She completed her fellowship in pediatric hematology/oncology here at UT Southwestern and was mentored in her research on epigenetic regulation of myeloid malignancies and treatment resistance at by Dr. Jian Xu, in his lab at the Children's Resaerch Institute. While in her fellowship and on into her early faculty appointment, Dr. Dickerson earned a masters of science in clinical sciences from the Center for Translational Medicine as an NIH KL2 scholar.

Dr. Dickerson's clinical interest is pediatric hematology with an emphasis on bone marrow failure disorders and cancer predisposition, as well as thalassemia/dyserythropoietic anemias.  Her research interest is in predisposition and transformation to myeloid malignancies: acute myelogenous leukemia (AML), myeloproliferative disorders (MPD), and myelodysplastic syndromes (MDS) in children. Dr. Dickerson conducts an investigator initiated study to evaluate childhood cancer survivors for clonal hematopoiesis and inflammation, as well as many industry/consortia-sponsored studies in bone marrow failure and other rare hematologic diseases.

Medical School

Indiana University School of Medicine (2011)

Residency

Ohio State University/Nationwide Children's Hospital (2014), Pediatrics

Fellowship

UT Southwestern/Children's Medical Center (2017), Pediatric Hematology/oncology

Graduate School

UT Southwestern Graduate School of Biomedical Sciences (2018)

Other Post Graduate Training

UT Southwestern Graduate School of Biomedical Sciences (2018)

• Acute myelogenous leukemia
• Epigenetics
• Leukemia predisposition
• Malignant transformation in inherited bone marrow failure (BMF) syndromes
• Myelodysplastic syndrome
• Myeloproliferative disorders

Featured Publications

Structural Variation Cooperates with Permissive Chromatin to Control Enhancer Hijacking-Mediated Oncogenic Transcription.

Botten G, Zhang Y, Dudnyk K, Kim YJ, Liu X, Sanders JT, Imanci A, Droin NM, Cao H, Kaphle P, Dickerson KE, Kumar KR, Chen M, Chen W, Solary E, Ly P, Zhou J, Xu J, Blood 2023 Mar

Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance.

Lyu J, Liu Y, Gong L, Chen M, Madanat YF, Zhang Y, Cai F, Gu Z, Cao H, Kaphle P, Kim YJ, Kalkan FN, Stephens H, Dickerson KE, Ni M, Chen W, Patel P, Mims AS, Borate U, Burd A, Cai SF, Yin CC, You MJ, Chung SS, Collins RH, DeBerardinis RJ, Liu X, Xu J, Cancer Discov 2022 Oct

Immature platelet fraction as a biomarker for disease severity in pediatric respiratory Coronavirus Disease 2019.

Lee NC, Demir YK, Ashraf B, Ibrahim I, Bat T, Dickerson KE, J Pediatr 2022 Aug

Convergence of oncogenic cooperation at single-cell and single-gene levels drives leukemic transformation.

Liu Y, Gu Z, Cao H, Kaphle P, Lyu J, Zhang Y, Hu W, Chung SS, Dickerson KE, Xu J, Nat Commun 2021 11 12 1 6323

SLC25A38 Congenital Sideroblastic Anemia: Phenotypes and genotypes of 31 individuals from 24 families, including 11 novel mutations, and a review of the literature.

Heeney MM, Berhe S, Campagna DR, Oved JH, Kurre P, Shaw PJ, Teo J, Shanap MA, Hassab HM, Glader BE, Shah S, Yoshimi A, Ameri A, Antin JH, Boudreaux J, Briones M, Dickerson KE, Fernandez CV, Farah R, Hasle H, Keel SB, Olson TS, Powers JM, Rose MJ, Shimamura A, Bottomley SS, Fleming MD, Hum Mutat 2021 Jul

Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia.

Gu Z, Liu Y, Zhang Y, Cao H, Lyu J, Wang X, Wylie A, Newkirk SJ, Jones AE, Lee M, Botten GA, Deng M, Dickerson KE, Zhang CC, An W, Abrams JM, Xu J, Nat Genet 2021 05 53 5 672-682

Therapy Response and Outcome Explained by Leukemia Cell of Origin.

Gu Z, Dickerson KE, Xu J, Cancer Discov 2020 10 10 10 1445-1447

Diagnosis and treatment of pediatric myelodysplastic syndromes: A survey of the North American Pediatric Aplastic Anemia Consortium.

Nakano TA, Lau BW, Dickerson KE, Wlodarski M, Pollard J, Shimamura A, Hofmann I, Sasa G, Elghetany T, Cada M, Dror Y, Ding H, Allen SW, Hanna R, Campbell K, Olson TS, Pediatr Blood Cancer 2020 10 67 10 e28652

A study assessing the feasibility of randomization of pediatric and young adult patients between matched unrelated donor bone marrow transplantation and immune-suppressive therapy for newly diagnosed severe aplastic anemia: A joint pilot trial of the North American Pediatric Aplastic Anemia Consortium and the Pediatric Transplantation and Cellular Therapy Consortium.

Pulsipher MA, Lehmann LE, Bertuch AA, Sasa G, Olson T, Nakano T, Gilio A, Burroughs LM, Lipton JM, Huang JN, Dickerson K, Bertaina A, Zhuang C, Malsch M, Fleming M, Weller E, Shimamura A, Williams DA, Pediatr Blood Cancer 2020 Aug e28444

Connecting the Dots From Fever of Unknown Origin to Myelodysplastic Syndrome: GATA2 Haploinsufficiency.

Montiel-Esparza R, Reys B, Rogers ZR, Evans AS, Wysocki CA, Timmons C, Dickerson KE, J Pediatr Hematol Oncol 2020 07 42 5 e365-e368

• Dr George Buchanan Teaching Award for Excellence in Pediatric Hematology/Oncology Fellow Education
  UT Southwestern Medical Center (2023)
• Wipe Out Kids Cancer Grant Recipient
  Children's Health/UT Southwestern Medical Center (2022)
• Dr George Buchanan Teaching Award for Excellence in Pediatric Hematology/Oncology Fellow Education
  UT Southwestern Medical Center (2021)
• Texas Monthly Super Doctors
  Rising Star (2020-2022)
• Hope Scholar Award
  Hyundai Hope on Wheels (2019)
• Pediatric Loan Repayment Award
  National Institutes of Health/National Cancer Institute (2018)
• "Call for Cure" Award Recipient
  Children's Cancer Fund (2017)
• Young Investigator Award
  Hyundai Hope on Wheels (2017)
• Certificate in Academic Medicine
  Nationwide Children's Hospital (2014)
• Certificate in Global Health
  Nationwide Children's Hospital (2014)
• Integrated Research Pathway/American Board of Pediatrics
  Nationwide Childrens Hospital/The Ohio State University, Dr. Michael Caligiuri Laboratory (2012)
• Community Service Award
  Indiana University School of Medicine (2011)
• E. Jane Brownley Award
  Department of Pediatrics, Indiana University School of Medicine (2011)
• Member, Gold Humanism Honorary Society
  (2010)
• Red Shoes Award
  Riley Hospital for Children (2010)
• Post-Baccalaureate Intramural Research Training Award
  National Institutes of Health/National Institute of Diabetes, Digestive, and Kidney disorders, Dr. Lee Weinstein Laboratory (2006)
• Member, Phi Beta Kappa
  (2005)

• American Academy of Pediatrics (2011)
• American Association for Cancer Research (2012-2017)
• American Society of Clinical Oncology/American Society of Pediatric Hematology Oncology (2014)
• Children's Oncology Group (2014)
• North American Pediatric Aplastic Anemia Consortium (2017)
• The American Society of Hematology (2014)