Margaret Pearle, M.D., Ph.D. Titles and Appointments Professor Endowed Title Dr. Ralph C. Smith Distinguished Chair in Urologic Education School Medical School Department Urology | Internal Medicine You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Margaret Pearle, M.D., Ph.D., is a Professor with joint appointments in UT Southwestern Medical Center's Department of Urology and the Mineral Metabolism Center, and is holder of the Ralph C. Smith Distinguished Chair in Urologic Education. She sees patients who need medical or surgical treatment for kidney stones. Dr. Pearle received her medical degree from the University of Chicago and completed her residency at Northwestern University Medical Center. She attended Washington University School of Medicine for her fellowship. Her research interests include evaluation of dietary and medical therapies for kidney stone prevention, assessment of outcomes for minimally invasive surgical treatments, and development and assessment of resident teaching tools. She has published and spoken extensively on these topics. Texas Monthly has named Dr. Pearle a Super Doctor. She is a Fellow of the American College of Surgeons, a Trustee of the American Board of Urology, a member of the American Association of Genitourinary Surgeons and the American Urological Association, and a member of the Board of Directors of the Endourological Society. Education Medical School University of Chicago (1987) Internship Northwestern University Medical Center (1988), General Surgery Residency Northwestern University Medical Center (1993), Urology Fellowship Washington University in St. Louis School of Medicine (1994), Urology Research Interest Medical therapy for stone disease Minimally invasive surgical therapy for stone disease Surgical education and use of virtual reality simulation Urological outcomes research in endourology and stone disease Publications Featured Publications Prospective, randomized trial comparing shock wave lithotripsy and ureteroscopy for lower pole calyceal calculi 1 cm or less in size. Pearle, M. S., Lingeman, J. E., Leveillee, R., Kuo, R., Preminger, G. M., Nadler, R. B., Macaluso, J., Monga, M. Kumar, U., Dushinski, J., Albala, D. M., Wolf, J. S. Jr., Assimos, D., Fabrizio, M., Munch, L, C., Nakada, S. Y., Auge, B., Honey, J., Ogan, K., Pattaras, J., McDougall, E. M., Averch, T., D., Turk, T., Pietrow, P. and Watkins. S. J. Urol. 2005 173 2005-2009 Urologic Diseases in America Project: Urolithiasis Pearle, M. S., Calhoun, E. A., Curhan, G. C. and The Urologic Diseases in America Project: J. Urol. 2005 173 848-857 AUA Nephrolithiasis Guideline Panel. Chapter 1: AUA guideline on management of staghorn calculi: diagnosis and treatment recommendations Preminger, G. M., Assimos, D. G., Lingeman, J. E., Nakada, S. Y., Pearle, M. S., Wolf, J. S. Jr. J. Urol. 2005 173 1991-2000 Cost effectiveness of medical management strategies for nephrolithiasis Lotan Y., Cadeddu, J.A., Roehrborn, C.G., Pak, C.Y.C. and Pearle, M.S. J Urol 2004 172 667-671 Effect of ascorbic acid consumption on urinary stone risk factors Traxer, O., Huet, B., Poindexter, J., Pak, C.Y.C. and Pearle, M.S. J Urol 2003 170 397-401 Predictors of Persistent Residual Stones After Second Look Percutaneous Nephrolithotomy. Dai JC, Trivedi H, Kommidi V, Antonelli JA, Pearle MS, Johnson BA, J Endourol 2024 Dec Predicting urinary stone recurrence: a joint model analysis of repeated 24-hour urine collections from the MSTONE database. Kong Z, Johnson BA, Maalouf NM, Nakada SY, Tracy CR, Steinberg RL, Miller N, Antonelli JA, Lotan Y, Pearle MS, Liu YL, Urolithiasis 2024 Nov 52 1 156 International Alliance of Urolithiasis (IAU) consensus on miniaturized percutaneous nephrolithotomy. Zeng GH, Zhong W, Mazzon G, Zhu W, Lahme S, Khadgi S, Desai J, Agrawal M, Schulsinger D, Gupta M, Montanari E, Martinez JML, Almousawi S, Malonzo VEF, Sriprasad S, Durutovic O, Arumuham V, Ferretti S, Kamal W, Xu KW, Cheng F, Gao XF, Cheng JW, Somani B, Duvdevani M, Git KA, Seitz C, Bernardo N, Ibrahim TAA, Aquino A, Yasui T, Fiori C, Knoll T, Papatsoris A, Gadzhiev N, Zhanbyrbekuly U, Angerri O, Ramos HL, Saltirov I, Moussa M, Giusti G, Vicentini F, Suarez EB, Pearle M, Preminger GM, Wu QH, Durutovic O, Ghani K, Maroccolo M, Brehmer M, Osther PJ, Zawadzki M, Tursunkulov A, Kytaibekovich MN, Abuvohidov AA, Lara CAR, Noori Z, Zanetti SP, Shrestha S, de la Rosette J, Denstedt J, Ye ZQ, Sarica K, Choong S, Mil Med Res 2024 Oct 11 1 70 Thulium Fiber Laser Versus Holmium:Yttrium Aluminum Garnet for Lithotripsy: Which Is the Winner? Traxer O, Pearle M, Eur Urol 2024 Jun 85 6 541-542 The relationship between the force applied and perceived by the surgeon during ureteral access sheath placement: ex-vivo experimental model. Tefik T, Ergül RB, Osther P, Giusti G, Preminger GM, Straub M, Rassweiler JJ, Montanari E, Brehmer M, Seitz C, Grasso M, Pearle M, Proietti S, Cloutier J, Gunver M, Nane I, Ozcan F, Traxer O, World J Urol 2024 May 42 1 329 Results 1-10 of 16 1 2 Next Last Honors & Awards Gold Cytoscope AwardAmerican Urological Association (2003) First Place, Samuel Ambrose Socioeconomic Essay Contest at the American Urological Association Annual Meeting in Orlando, FloridaCost effective treatment of ureteropelvic junction obstruction: A decision tree analysis" (2002) Ralph Smith Distinguished Chair in Urological Education (2002) Royal College of Surgeons Travelling FellowshipThe Royal College of Surgeons (1998) Professional Associations/Affiliations American Association of Genitourinary Surgeons American Urological Association Endourological Society Fellow, American College of Surgeons Research in Calculus Kinetics (R.O.C.K.) Society