Sam Wang, M.D., is an Assistant Professor in the Division of Surgical Oncology in the Department of Surgery at UT Southwestern Medical Center. His clinical focus includes cancers of the liver, pancreas, stomach, and bile duct.

Dr. Wang graduated from Stanford University, where he received a B.S. with honors in biological science and an A.B. with high honors in history. He attended medical school at Duke University School of Medicine and completed an internship and residency in general surgery at the University of California, San Francisco. He then received advanced training in complex general surgical oncology through a fellowship at Memorial Sloan Kettering Cancer Center. He joined the UT Southwestern faculty in 2014.

In the lab, Dr. Wang is interested in how the normal regenerative process mutates and leads to cancer. In addition, he is studying the molecular mechanisms behind outcome disparities that Hispanic gastric cancer patients face. The goals for his research are to identify new diagnostic and therapeutic strategies to improve outcomes for these patients.

Dr. Wang is a member of the Society of Surgical Oncology, the Association for Academic Surgery, the American Association for Cancer Research, and the American College of Surgeons. He is fluent in Mandarin.


Medical School
Duke University School of Medicine (2005)
UCSF School of Medicine (2012), Surgery
Memorial Sloan-Kettering Cancer Center (2014), Surgical Oncology

Research Interest

  • Epigenetic changes in cancer
  • Gastric, pancreas, and liver cancer
  • Molecular mechanisms behind disparities in cancer outcomes
  • Role of tissue injury and regeneration on cancer formation


Featured Publications LegendFeatured Publications

Improved Survival in Surgically Resected Distal Cholangiocarcinoma Treated with Adjuvant Therapy: a Propensity Score Matched Analysis.
Hester C, Nassour I, Adams-Huet B, Augustine M, Choti MA, Minter RM, Mansour JC, Polanco PM, Porembka MR, Wang SC, Yopp AC J. Gastrointest. Surg. 2018 Jul
Comparative outcomes of adenosquamous carcinoma of the pancreas: An analysis of the National Cancer Database.
Hester CA, Augustine MM, Choti MA, Mansour JC, Minter RM, Polanco PM, Porembka MR, Wang SC, Yopp AC J Surg Oncol 2018 Jun
Determining the Adequate Examined Lymph Node Count in Resected Ampullary Adenocarcinoma-A National Cohort Study.
Nassour I, Christie A, Choti MA, Mansour JC, Minter RM, Polanco PM, Augustine MM, Porembka MR, Xie XJ, Wang SC J. Gastrointest. Surg. 2018 Mar
Adjuvant Therapy Is Associated With Improved Survival in Resected Perihilar Cholangiocarcinoma: A Propensity Matched Study.
Nassour I, Mokdad AA, Porembka MR, Choti MA, Polanco PM, Mansour JC, Minter RM, Wang SC, Yopp AC Ann. Surg. Oncol. 2018 Feb
Reply to Grant, William: Obesity and vitamin D status may help explain the racial and ethnic disparities in ampullary cancer survival rates.
Nassour I, Wang SC J Surg Oncol 2018 Feb
Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer.
Sun X, Wang SC, Wei Y, Luo X, Jia Y, Li L, Gopal P, Zhu M, Nassour I, Chuang JC, Maples T, Celen C, Nguyen LH, Wu L, Fu S, Li W, Hui L, Tian F, Ji Y, Zhang S, Sorouri M, Hwang TH, Letzig L, James L, Wang Z, Yopp AC, Singal AG, Zhu H Cancer Cell 2018 Jan 33 1 151-152
Robotic-assisted versus laparoscopic pancreaticoduodenectomy: oncological outcomes.
Nassour I, Choti MA, Porembka MR, Yopp AC, Wang SC, Polanco PM Surg Endosc 2017 Dec
Adoption of evidence-based novel therapies in the treatment of gastric cancer: A national observational study.
Mokdad AA, Ali A, Yopp AC, Polanco PM, Nassour I, Mansour JC, Choti MA, Minter RM, Wang SC, Porembka MR Cancer 2017 Dec
Reply to "Pretreatment Neutrophil to Lymphocyte Ratio Independently Predicts Disease-specific Survival in Patients With Resectable Gastroesophageal Junction and Gastric Cancer".
Wang SC, Coit DG Ann. Surg. 2017 Dec 266 6 e77
Association of Adjuvant Therapy with Improved Survival in Ampullary Cancer: A National Cohort Study.
Nassour I, Hynan LS, Christie A, Minter RM, Yopp AC, Choti MA, Mansour JC, Porembka MR, Wang SC J. Gastrointest. Surg. 2017 Nov

Honors & Awards

  • Jacobson Promising Investigator Award
    American College of Surgeons (2019)
  • Faculty Research Fellowship
    American College of Surgeons (2017-2019)
  • Health Care Disparities Research Award
    Society for Surgery of the Alimentary Tract (2017-2019)
  • Outstanding Mentor, Center for Translational Medicine
    University of Texas Southwestern Medical Center (2017)
  • Disease-Oriented Clinical Scholar
    University of Texas Southwestern Medical Center (2015-2018)
  • Conquer Cancer Foundation Merit Award
    American Society of Clinical Oncology (2014)
  • Outstanding Resident Achievement Award
    Department of Surgery, University of California, San Francisco (2012)

Professional Associations/Affiliations

  • Society for Surgery of the Alimentary Tract (2016)
  • Dallas Country Medical Society (2014)
  • Texas Medical Association (2014)
  • Association for Academic Surgery (2013)
  • Society of Surgical Oncology (2013)
  • UCSF Naffziger Surgical Society (2012)
  • American Association for Cancer Research (2008)
  • American Association for Cancer Research (2008)
  • American College of Surgeons (2005)