Kevin Dean, Ph.D.

• Intelligent multiplexed imaging approaches.
• Molecular interrogation of early metastatic colonization events.

 Featured Publications

Real-time multi-angle projection imaging of biological dynamics.

Chang BJ, Manton JD, Sapoznik E, Pohlkamp T, Terrones TS, Welf ES, Murali VS, Roudot P, Hake K, Whitehead L, York AG, Dean KM, Fiolka R, Nat Methods 2021 Jun

A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics.

Sapoznik E, Chang BJ, Huh J, Ju RJ, Azarova EV, Pohlkamp T, Welf ES, Broadbent D, Carisey AF, Stehbens SJ, Lee KM, Marín A, Hanker AB, Schmidt JC, Arteaga CL, Yang B, Kobayashi Y, Tata PR, Kruithoff R, Doubrovinski K, Shepherd DP, Millett-Sikking A, York AG, Dean KM, Fiolka RP, Elife 2020 11 9

Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution.

Chakraborty T, Driscoll MK, Jeffery E, Murphy MM, Roudot P, Chang BJ, Vora S, Wong WM, Nielson CD, Zhang H, Zhemkov V, Hiremath C, De La Cruz ED, Yi Y, Bezprozvanny I, Zhao H, Tomer R, Heintzmann R, Meeks JP, Marciano DK, Morrison SJ, Danuser G, Dean KM, Fiolka R, Nat. Methods 2019 Nov 16 11 1109-1113

Robust and automated detection of subcellular morphological motifs in 3D microscopy images.

Driscoll MK, Welf ES, Jamieson AR, Dean KM, Isogai T, Fiolka R, Danuser G, Nat. Methods 2019 Oct 16 10 1037-1044

Pre-complexation of talin and vinculin without tension is required for efficient nascent adhesion maturation.

Han SJ, Azarova EV, Whitewood AJ, Bachir A, Guttierrez E, Groisman A, Horwitz AR, Goult BT, Dean KM, Danuser G, Elife 2021 03 10

Universal light-sheet generation with field synthesis.

Chang BJ, Kittisopikul M, Dean KM, Roudot P, Welf ES, Fiolka R Nat. Methods 2019 Mar 16 3 235-238

• Cecil H. and Ida Green Center for Systems Biology (2021)
• Department of Cell Biology (2018)
• Lyda Hill Department of Bioinformatics (2021)
• Microscopy Innovation Lab (2018)