Research Interest

  • Age-related macular degeneration
  • Chemical biology
  • Drug discovery
  • Extracellular matrix proteins
  • Inherited retinal dystrophies
  • Ocular protein misfolding diseases
  • Stress-responsive signaling

Publications

Featured Publications LegendFeatured Publications

Prospective Application of Activity-Based Proteomic Profiling in Vision Research-Potential Unique Insights into Ocular Protease Biology and Pathology.
Peng H, Hulleman JD, Int J Mol Sci 2019 Aug 20 16
Deducing the presence of proteins and proteoforms in quantitative proteomics.
Bamberger C, Martínez-Bartolomé S, Montgomery M, Pankow S, Hulleman JD, Kelly JW, Yates JR Nat Commun 2018 Jun 9 1 2320
High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production.
Wong MY, Doan ND, DiChiara AS, Papa LJ, Cheah JH, Soule CK, Watson N, Hulleman JD, Shoulders MD Biochemistry 2018 Apr
Mapping wild-type and R345W fibulin-3 intracellular interactomes.
Hulleman JD, Genereux JC, Nguyen A Exp. Eye Res. 2016 Oct
A Novel Luciferase Assay For Sensitively Monitoring Myocilin Variants in Cell Culture.
Zadoo S, Nguyen A, Zode G, Hulleman JD Invest. Ophthalmol. Vis. Sci. 2016 Apr 57 4 1939-1950
Malattia Leventinese/Doyne Honeycomb Retinal Dystrophy: Similarities to Age-Related Macular Degeneration and Potential Therapies.
Hulleman JD Adv. Exp. Med. Biol. 2016 854 153-8
Evidence of Alternative Cystatin C Signal Sequence Cleavage Which Is Influenced by the A25T Polymorphism.
Nguyen A, Hulleman JD PLoS ONE 2016 11 2 e0147684

Books

Featured Books Legend Featured Books

Alpha-Synuclein self-assembly in Parkinson's disease: Insights from biophysical analyses. In Protein Misfolding in Biology and Disease

Rochet JC and Hulleman JD (2009). Trivandrum, India, Research Signpost

Honors & Awards

  • Bright Focus Foundation
    Macular Degeneration Research Award (2018-2020)
  • National Institutes of Health
    R01EY027785 (2018-2023)
  • National Institutes of Health
    R21EY028261 (2017-2019)
  • Bright Focus Foundation
    Macular Degeneration Research Award (2016-2018)
  • Karl Kirchgessner Foundation
    Vision Research Grant (2016-2019)
  • Research to Prevent Blindness
    Career Development Award (2015-2019)