Orhan K. Öz, M.D., Ph.D., is Professor of Radiology and Interim Chief of Nuclear Medicine at UT Southwestern Medical Center, and holder of the Wechun Pak Professorship of Bone Biophysics. He is also Professor of Biomedical Engineering at UT Southwestern Graduate School of Biomedical Sciences, and Medical Director of Nuclear Medicine at Parkland Memorial Hospital. His clinical interests include nuclear medicine, radiology, thyroid and musculoskeletal diseases, cancer and cancer imaging, with a particular interest in neuroendocrine malignancies.
Dr. Öz holds a bachelor’s degree in biology, chemistry, and mathematics from Morehouse College, and a master’s degree in applied mathematics from Clark Atlanta University. After receiving his medical degree and doctoral degree in biophysics from Stanford University, he completed residency training in radiology at UT Southwestern. During residency Dr. Öz was a member of the Clinical Scholars track during which he did a post-doctoral fellowship pursuing advanced training in radiology and molecular biology. After joining the faculty, he received advanced training in proton emission tomography (PET) at the University of California – Los Angeles.
A range of research interests
Although the majority of his time is dedicated to clinical practice, Dr. Öz is highly involved in research. His interests include imaging pancreatic beta cells, imaging of diabetic foot infections, novel imaging probe development, and investigating the mechanisms underlying estrogen regulation of bone mass and metabolism. His research has resulted in numerous publications throughout his career, including the publication of a single-photon emission computed tomography (SPECT) and computed tomography (CT) based scoring system to stage the severity of foot infections in people with diabetes.
A career marked by service
Among Dr. Öz’s administrative responsibilities, he serves as Co-Director of the Preclinical Nuclear Imaging Laboratory and the Molecular Imaging Probe Laboratory at UT Southwestern, Medical Director of Nuclear Medicine for Parkland Health & Hospital System (PHHS) as well as Chief of Radiation Safety at PHHS. He also serves on numerous committees, including Parkland’s Radiology Performance Improvement Committee, and UT Southwestern’s Radiation Safety Advisory Committee (past chair), Radioactive Drug Search Research Committee and the IRB Subcommittee on Human Use of Radiation. Dr. Öz’s committee service also extends internationally, including membership on the Credentialing Committee and Scientific Advisory Council of the International Society of Clinical Densitometry.
Dr. Öz is a member of several national and international professional societies, including the Society of Nuclear Medicine and Molecular Imaging (SNMMI), Radiological Society of North America (RSNA), American Society of Bone and Mineral Research (ASBMR), Endocrine Society, National Medical Association and the North American Neuroendocrine Tumor Society.
Robust editorial activity
In addition to authoring more than 66 research publications, Dr. Öz is a reviewer for multiple academic journals, including Bone, Laboratory Investigation, European Journal of Nuclear Medicine and Molecular Imaging, Journal of Bone and Mineral Research, Journal of Nuclear Medicine, Endocrine, Laboratory Investigation, Federation of American Societies for Experimental Biology, PLOS One and Cell Chemical Biology.
Dr. Öz is frequently invited to lecture nationally and internationally at numerous events, including conferences in Australia, Turkey and China. He has also received a number of grants and awards to support his research, and has been recognized by his peers for his contributions to the RSNA and SNMMI.
- Medical School
- Stanford University (1991)
- Parkland Health & Hospital System (1992), Diagnostic Radiology
- Parkland Health & Hospital System (1995), Diagnostic Radiology
- Imaging Pancreatic Beta cells
- Mechanism underlining estrogen regulation of bone mass and metabolism
- Tumor imaging
- Pathogenesis of Primary Hypercalciuria
- Moe OW, Zerwekh JE, Huang CL, Preisig PA, Oz OK, Pak CYC Clinical Cases in Mineral and Bone Metabolism 2004 1/1 13-19
- Biodistribution of Phosphodiester and Phosphorothioate siRNA
- Braasch DA, Paroo Z, Constantinescu A, Ren G, Oz OK, Mason RP, Corey DR Biorganic and Medicinal Chemistry Letters 2004 14 1139-1143
- Expression of aromatase in the human growth plate
- Oz OK, Millsaps R, Welch R, Birch J, Zerwekh JE J Molec Endocrinol 2001 27/2 249-253
- Bone has a sexually dimorphic response to aromatase deficiency
- Oz OK, Zerwekh JE, Fisher C, Graves K, Nanu L, Millsaps R, Simpson ER J Bone Min Res 2000 15 507-513
- Aromatase Deficiency Causes Altered Expression of Molecules Critical for Calcium Reabsorption in the Kidneys of Female Mice
- Orhan K. Oz, Asghar Hajibeigi, Kevin Howard, Carolyn L. Cummins, Monique van Abel, Rene J. M. Bindels, R. Ann Word, Makoto Kuro-o, Charles Y. C. Pak, Joseph E. Zerwekh Journal of Bone and Mineral Research in press
- Viable Mice with compound mutations in the Wnt/Dvl-pathway antagonists nkd1 and nkd2
- Zhang S, Cagatay T, Amanai M, Zhang M, Kline J, Castrillon DH, Ashfaq R, Oz OK, and Wharton KA Molecular and Cell Biology June 2007 27 4454-64
- Fortuitous detection of Pseudoaneurysm by three-phase bone scan
- Coskun ZU, Stewart CE, Robinson M, Beisert G, Rivera FJ, Oz OK Clinical Nuclear Medicine 2005 30 685-687
Honors & Awards
- The Wechun Pak Professorship of Bone Biophysics
Endowment to support independent research (2011)
- Career Development Award
National Institute of Child Health and Human Development (2000)
- Compton Dissertation Fellowship
Dissertation Fellowship (1987)
- Atlanta Rotary Club Award
Academic Excellence (1982)
- National Institute of Neurological and Communicative Disorders and Stroke
Exceptional Summer Employee Award (1982)
- Phi Beta Kappa
Academic Excellence (1980)
- American Society of Bone and Mineral Research
- Endocrine Society
- International Bone and Mineral Society
- National Medical Association
- Society of Nuclear Medicine