Eric Olson, Ph.D.

Undergraduate

Wake Forest Univ - Undergradua (1977), Biology

Undergraduate

Wake Forest Univ - Undergradua (1977), Chemistry

Graduate School

Wake Forest Univ - Sch of Medi (1981), Biochemistry

• Muscle Development
• Stem cells
• Transcriptional Regulation

Featured Publications

MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid ?-Oxidation.

Makarewich CA, Baskin KK, Munir AZ, Bezprozvannaya S, Sharma G, Khemtong C, Shah AM, McAnally JR, Malloy CR, Szweda LI, Bassel-Duby R, Olson EN Cell Rep 2018 Jun 23 13 3701-3709

Fusogenic micropeptide Myomixer is essential for satellite cell fusion and muscle regeneration.

Bi P, McAnally JR, Shelton JM, Sánchez-Ortiz E, Bassel-Duby R, Olson EN Proc. Natl. Acad. Sci. U.S.A. 2018 Mar

Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing.

Long C, Li H, Tiburcy M, Rodriguez-Caycedo C, Kyrychenko V, Zhou H, Zhang Y, Min YL, Shelton JM, Mammen PPA, Liaw NY, Zimmermann WH, Bassel-Duby R, Schneider JW, Olson EN Sci Adv 2018 Jan 4 1 eaap9004

Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy.

Amoasii L, Long C, Li H, Mireault AA, Shelton JM, Sanchez-Ortiz E, McAnally JR, Bhattacharyya S, Schmidt F, Grimm D, Hauschka SD, Bassel-Duby R, Olson EN Sci Transl Med 2017 Nov 9 418

Functional correction of dystrophin actin binding domain mutations by genome editing.

Kyrychenko V, Kyrychenko S, Tiburcy M, Shelton JM, Long C, Schneider JW, Zimmermann WH, Bassel-Duby R, Olson EN JCI Insight 2017 Sep 2 18

ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression.

Zhou H, Morales MG, Hashimoto H, Dickson ME, Song K, Ye W, Kim MS, Niederstrasser H, Wang Z, Chen B, Posner BA, Bassel-Duby R, Olson EN Genes Dev. 2017 Sep 31 17 1770-1783

KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination.

Ramirez-Martinez A, Cenik BK, Bezprozvannaya S, Chen B, Bassel-Duby R, Liu N, Olson EN Elife 2017 Aug 6

Mining for Micropeptides.

Makarewich CA, Olson EN Trends Cell Biol. 2017 May

Control of muscle formation by the fusogenic micropeptide myomixer.

Bi P, Ramirez-Martinez A, Li H, Cannavino J, McAnally JR, Shelton JM, Sánchez-Ortiz E, Bassel-Duby R, Olson EN Science 2017 Apr 356 6335 323-327

CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice.

Zhang Y, Long C, Li H, McAnally JR, Baskin KK, Shelton JM, Bassel-Duby R, Olson EN Sci Adv 2017 Apr 3 4 e1602814

• Eric N. Olson Mentorship Award established by International Society for Heart Research
  (2020)
• Edwin G. Conklin Medal in Developmental Biology
  (2019)
• Libin Prize for Excellence in Cardiovascular Research, Heritage Foundation, Canada
  (2017)
• Dallas Historical Society Award for Excellence in Medicine
  (2016)
• The Eugene Braunwald Mentorship Award, American Heart Association
  (2016)
• March of Dimes Prize in Developmental Biology
  (2013)
• Research Achievement Award, International Society for Heart Research
  (2013)
• Passano Award
  (2012)
• Fondation Lefoulon-Delalande Grand Prize for Science
  (2009)
• Pollin Prize in Pediatric Research
  (2005)
• Institute of Medicine
  (2001)
• National Academy of Sciences
  (2000)
• Pasarow Award in Cardiovascular Medicine
  (2000)

• Editorial Board, Circulation (1993)
• Editorial Board, Developmental Cell (2005)
• Editorial Board, EMBO Molecular Medicine (2008)
• Editorial Board, Molecular and Cellular Biology (1993)