
Eric Olson, Ph.D.
Professor & Chair
Endowed Title Annie and Willie Nelson Professorship in Stem Cell Research; Pogue Distinguished Chair in Research on Cardiac Birth Defects; The Robert A. Welch Distinguished Chair in Science
Department Molecular Biology
Graduate Programs Genetics, Development and Disease
Education
- Undergraduate
- Wake Forest Univ - Undergradua (1977), Biology
- Undergraduate
- Wake Forest Univ - Undergradua (1977), Chemistry
- Graduate School
- Wake Forest Univ - Sch of Medi (1981), Biochemistry
Research Interest
- Muscle Development
- Stem cells
- Transcriptional Regulation
Publications
Featured Publications
- MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid ?-Oxidation.
- Makarewich CA, Baskin KK, Munir AZ, Bezprozvannaya S, Sharma G, Khemtong C, Shah AM, McAnally JR, Malloy CR, Szweda LI, Bassel-Duby R, Olson EN Cell Rep 2018 Jun 23 13 3701-3709
- Fusogenic micropeptide Myomixer is essential for satellite cell fusion and muscle regeneration.
- Bi P, McAnally JR, Shelton JM, Sánchez-Ortiz E, Bassel-Duby R, Olson EN Proc. Natl. Acad. Sci. U.S.A. 2018 Mar
- Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing.
- Long C, Li H, Tiburcy M, Rodriguez-Caycedo C, Kyrychenko V, Zhou H, Zhang Y, Min YL, Shelton JM, Mammen PPA, Liaw NY, Zimmermann WH, Bassel-Duby R, Schneider JW, Olson EN Sci Adv 2018 Jan 4 1 eaap9004
- Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy.
- Amoasii L, Long C, Li H, Mireault AA, Shelton JM, Sanchez-Ortiz E, McAnally JR, Bhattacharyya S, Schmidt F, Grimm D, Hauschka SD, Bassel-Duby R, Olson EN Sci Transl Med 2017 Nov 9 418
- Functional correction of dystrophin actin binding domain mutations by genome editing.
- Kyrychenko V, Kyrychenko S, Tiburcy M, Shelton JM, Long C, Schneider JW, Zimmermann WH, Bassel-Duby R, Olson EN JCI Insight 2017 Sep 2 18
- ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression.
- Zhou H, Morales MG, Hashimoto H, Dickson ME, Song K, Ye W, Kim MS, Niederstrasser H, Wang Z, Chen B, Posner BA, Bassel-Duby R, Olson EN Genes Dev. 2017 Sep 31 17 1770-1783
- KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination.
- Ramirez-Martinez A, Cenik BK, Bezprozvannaya S, Chen B, Bassel-Duby R, Liu N, Olson EN Elife 2017 Aug 6
- Mining for Micropeptides.
- Makarewich CA, Olson EN Trends Cell Biol. 2017 May
- Control of muscle formation by the fusogenic micropeptide myomixer.
- Bi P, Ramirez-Martinez A, Li H, Cannavino J, McAnally JR, Shelton JM, Sánchez-Ortiz E, Bassel-Duby R, Olson EN Science 2017 Apr 356 6335 323-327
- CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice.
- Zhang Y, Long C, Li H, McAnally JR, Baskin KK, Shelton JM, Bassel-Duby R, Olson EN Sci Adv 2017 Apr 3 4 e1602814
Honors & Awards
- Eric N. Olson Mentorship Award established by International Society for Heart Research
(2020) - Edwin G. Conklin Medal in Developmental Biology
(2019) - Libin Prize for Excellence in Cardiovascular Research, Heritage Foundation, Canada
(2017) - Dallas Historical Society Award for Excellence in Medicine
(2016) - The Eugene Braunwald Mentorship Award, American Heart Association
(2016) - March of Dimes Prize in Developmental Biology
(2013) - Research Achievement Award, International Society for Heart Research
(2013) - Passano Award
(2012) - Fondation Lefoulon-Delalande Grand Prize for Science
(2009) - Pollin Prize in Pediatric Research
(2005) - Institute of Medicine
(2001) - National Academy of Sciences
(2000) - Pasarow Award in Cardiovascular Medicine
(2000)
Professional Associations/Affiliations
- Editorial Board, Circulation (1993)
- Editorial Board, Developmental Cell (2005)
- Editorial Board, EMBO Molecular Medicine (2008)
- Editorial Board, Molecular and Cellular Biology (1993)