Education

Medical School
David Geffen School of Medicine at UCLA (2005)
Residency
Harvard Medical School/Boston Children's Hospital (2007), Pediatrics
Residency
Children's Hospital - Boston (2010), Pediatric Neurology
Fellowship
Children's Hospital - Boston (2011), Behavioral Neurology

Research Interest

  • Autism and Neurodevelopmental Disorders
  • Cerebellar contribution to cognition and behavior
  • Neuronal circuits underlying behavioral disorders

Publications

Featured Publications LegendFeatured Publications

Cerebellar associative sensory learning defects in five mouse autism models.
Kloth AD, Badura A, Li A, Cherskov A, Connolly SG, Giovannucci A, Bangash MA, Grasselli G, Pe├▒agarikano O, Piochon C, Tsai PT, Geschwind DH, Hansel C, Sahin M, Takumi T, Worley PF, Wang SS Elife 2015 4
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1.
Di Nardo A, Wertz MH, Kwiatkowski E, Tsai PT, Leech JD, Greene-Colozzi E, Goto J, Dilsiz P, Talos DM, Clish CB, Kwiatkowski DJ, Sahin M Hum. Mol. Genet. 2014 Jul 23 14 3865-74
Copy number variation plays an important role in clinical epilepsy.
Olson H, Shen Y, Avallone J, Sheidley BR, Pinsky R, Bergin AM, Berry GT, Duffy FH, Eksioglu Y, Harris DJ, Hisama FM, Ho E, Irons M, Jacobsen CM, James P, Kothare S, Khwaja O, Lipton J, Loddenkemper T, Markowitz J, Maski K, Megerian JT, Neilan E, Raffalli PC, Robbins M, Roberts A, Roe E, Rollins C, Sahin M, Sarco D, Schonwald A, Smith SE, Soul J, Stoler JM, Takeoka M, Tan WH, Torres AR, Tsai P, Urion DK, Weissman L, Wolff R, Wu BL, Miller DT, Poduri A Ann. Neurol. 2014 Jun 75 6 943-58
Both maternal and pup genotype influence ultrasonic vocalizations and early developmental milestones in tsc2 (+/-) mice.
Greene-Colozzi EA, Sadowski AR, Chadwick E, Tsai PT, Sahin M Epilepsy Res Treat 2014 2014 784137
A magnetic resonance imaging study of cerebellar volume in tuberous sclerosis complex.
Weisenfeld NI, Peters JM, Tsai PT, Prabhu SP, Dies KA, Sahin M, Warfield SK Pediatr. Neurol. 2013 Feb 48 2 105-10
Prenatal rapamycin results in early and late behavioral abnormalities in wildtype C57BL/6 mice.
Tsai PT, Greene-Colozzi E, Goto J, Anderl S, Kwiatkowski DJ, Sahin M Behav. Genet. 2013 Jan 43 1 51-9
Graded loss of tuberin in an allelic series of brain models of TSC correlates with survival, and biochemical, histological and behavioral features.
Yuan E, Tsai PT, Greene-Colozzi E, Sahin M, Kwiatkowski DJ, Malinowska IA Hum. Mol. Genet. 2012 Oct 21 19 4286-300
Mechanisms of neurocognitive dysfunction and therapeutic considerations in tuberous sclerosis complex.
Tsai P, Sahin M Curr. Opin. Neurol. 2011 Apr 24 2 106-13
Cognitive and behavioral characterization of 16p11.2 deletion syndrome.
Hanson E, Nasir RH, Fong A, Lian A, Hundley R, Shen Y, Wu BL, Holm IA, Miller DT J Dev Behav Pediatr 2010 Oct 31 8 649-57
A critical role of erythropoietin receptor in neurogenesis and post-stroke recovery.
Tsai PT, Ohab JJ, Kertesz N, Groszer M, Matter C, Gao J, Liu X, Wu H, Carmichael ST J. Neurosci. 2006 Jan 26 4 1269-74