Peter Tsai, M.D., Ph.D.

Associate Professor

School: Medical School
Department: Neurology | Neuroscience | Pediatrics | Psychiatry
Graduate Programs: Neuroscience

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Education

Medical School: David Geffen School of Medicine at UCLA (2005)
Residency: Harvard Medical School/Boston Children's Hospital (2007), Pediatrics
Residency: Children's Hospital - Boston (2010), Pediatric Neurology
Fellowship: Children's Hospital - Boston (2011), Behavioral Neurology

Research Interest

Autism and Neurodevelopmental Disorders
Cerebellar contribution to cognition and behavior
Neuronal circuits underlying behavioral disorders

Publications

Featured Publications

Cerebellar contribution to autism-relevant behaviors in fragile X syndrome models.: Gibson JM, Vazquez AH, Yamashiro K, Jakkamsetti V, Ren C, Lei K, Dentel B, Pascual JM, Tsai PT, Cell Rep 2023 Dec 42 12 113533
Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure model.: Dentel B, Angeles-Perez L, Ren C, Jakkamsetti V, Holley AJ, Caballero D, Oh E, Gibson J, Pascual JM, Huber KM, Tu BP, Tsai PT, iScience 2022 May 25 5 104334
A critical period for development of cerebellar-mediated autism-relevant social behavior.: Gibson JM, Howland CP, Ren C, Howland C, Vernino A, Tsai PT, J Neurosci 2022 Feb
Adaptive Prediction for Social Contexts: The Cerebellar Contribution to Typical and Atypical Social Behaviors.: Stoodley CJ, Tsai PT, Annu Rev Neurosci 2021 Jul 44 475-493
Regulation of autism-relevant behaviors by cerebellar-prefrontal cortical circuits.: Kelly E, Meng F, Fujita H, Morgado F, Kazemi Y, Rice LC, Ren C, Escamilla CO, Gibson JM, Sajadi S, Pendry RJ, Tan T, Ellegood J, Basson MA, Blakely RD, Dindot SV, Golzio C, Hahn MK, Katsanis N, Robins DM, Silverman JL, Singh KK, Wevrick R, Taylor MJ, Hammill C, Anagnostou E, Pfeiffer BE, Stoodley CJ, Lerch JP, du Lac S, Tsai PT, Nat Neurosci 2020 09 23 9 1102-1110
Sensitive Periods for Cerebellar-Mediated Autistic-like Behaviors.: Tsai PT, Rudolph S, Guo C, Ellegood J, Gibson JM, Schaeffer SM, Mogavero J, Lerch JP, Regehr W, Sahin M Cell Rep 2018 Oct 25 2 357-367.e4
Altered cerebellar connectivity in autism and cerebellar-mediated rescue of autism-related behaviors in mice.: Stoodley CJ, D'Mello AM, Ellegood J, Jakkamsetti V, Liu P, Nebel MB, Gibson JM, Kelly E, Meng F, Cano CA, Pascual JM, Mostofsky SH, Lerch JP, Tsai PT Nat. Neurosci. 2017 Dec 20 12 1744-1751
Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.: Tsai PT, Hull C, Chu Y, Greene-Colozzi E, Sadowski AR, Leech JM, Steinberg J, Crawley JN, Regehr WG, Sahin M Nature 2012 Aug 488 7413 647-51
Synaptic BMAL1 phosphorylation controls circadian hippocampal plasticity.: Barone I, Gilette NM, Hawks-Mayer H, Handy J, Zhang KJ, Chifamba FF, Mostafa E, Johnson-Venkatesh EM, Sun Y, Gibson JM, Rotenberg A, Umemori H, Tsai PT, Lipton JO, Sci Adv 2023 Oct 9 43 eadj1010
Cerebellar Dysfunction in Autism Spectrum Disorders: Deriving Mechanistic Insights from an Internal Model Framework.: Kelly E, Escamilla CO, Tsai PT, Neuroscience 2021 05 462 274-287