Education

Medical School
David Geffen School of Medicine at UCLA (2005)
Residency
Harvard Medical School/Boston Children's Hospital (2007), Pediatrics
Residency
Children's Hospital - Boston (2010), Pediatric Neurology
Fellowship
Children's Hospital - Boston (2011), Behavioral Neurology

Research Interest

  • Autism and Neurodevelopmental Disorders
  • Cerebellar contribution to cognition and behavior
  • Neuronal circuits underlying behavioral disorders

Publications

Featured Publications LegendFeatured Publications

Sensitive Periods for Cerebellar-Mediated Autistic-like Behaviors.
Tsai PT, Rudolph S, Guo C, Ellegood J, Gibson JM, Schaeffer SM, Mogavero J, Lerch JP, Regehr W, Sahin M Cell Rep 2018 Oct 25 2 357-367.e4
Aberrant Proteostasis of BMAL1Ā Underlies Circadian Abnormalities in a Paradigmatic mTOR-opathy.
Lipton JO, Boyle LM, Yuan ED, Hochstrasser KJ, Chifamba FF, Nathan A, Tsai PT, Davis F, Sahin M Cell Rep 2017 Jul 20 4 868-880
The Role of the Pediatric Cerebellum in Motor Functions, Cognition, and Behavior: A Clinical Perspective.
Salman MS, Tsai P Neuroimaging Clin. N. Am. 2016 Aug 26 3 317-29
Autism and cerebellar dysfunction: Evidence from animal models.
Tsai PT Semin Fetal Neonatal Med 2016 May
Reversal of neurobehavioral social deficits in dystrophic mice using inhibitors of phosphodiesterases PDE5A and PDE9A.
Alexander MS, Gasperini MJ, Tsai PT, Gibbs DE, Spinazzola JM, Marshall JL, Feyder MJ, Pletcher MT, Chekler EL, Morris CA, Sahin M, Harms JF, Schmidt CJ, Kleiman RJ, Kunkel LM Transl Psychiatry 2016 6 9 e901
Cerebellar associative sensory learning defects in five mouse autism models.
Kloth AD, Badura A, Li A, Cherskov A, Connolly SG, Giovannucci A, Bangash MA, Grasselli G, PeƱagarikano O, Piochon C, Tsai PT, Geschwind DH, Hansel C, Sahin M, Takumi T, Worley PF, Wang SS Elife 2015 4
The role of cerebellar circuitry alterations in the pathophysiology of autism spectrum disorders.
Mosconi MW, Wang Z, Schmitt LM, Tsai P, Sweeney JA Front Neurosci 2015 9 296
Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1.
Di Nardo A, Wertz MH, Kwiatkowski E, Tsai PT, Leech JD, Greene-Colozzi E, Goto J, Dilsiz P, Talos DM, Clish CB, Kwiatkowski DJ, Sahin M Hum. Mol. Genet. 2014 Jul 23 14 3865-74