Bradley Lega, M.D. Associate Professor Endowed Title William Kemp Clark Chair of Neurological Surgery School Medical School Department Neurological Surgery | Neurology | Psychiatry Graduate Programs Neuroscience You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Download Curriculum Vitae Dr. Lega's research is focused on the electrophsyiology of human memory, principally episodic memory. He has collaborations with Dr. Mick Rugg at the UT Dallas Center for Vital Longevity, Dr. Gena Konopka of Neuroscience, and others. Dr. Lega's research training was chiefly with Dr. Michael Kahana of the University of Pennsylvania, with whom he completed a post doctroal fellowship. Education Medical School Baylor College of Medicine (2006) Internship University of Pennsylvania Health System (2007), General Surgery Residency University of Pennsylvania (2013), Neurological Surgery Fellowship Cleveland Clinic Foundation (2014), Epilepsy Research Interest Hippocampal electrophysiology Machine learning Memory encoding and retrieval Restoring memory function after brain injury Publications Featured Publications Hippocampal Theta Oscillations Support Successful Associative Memory Formation. Kota S, Rugg MD, Lega BC, J Neurosci 2020 12 40 49 9507-9518 Time cells in the human hippocampus and entorhinal cortex support episodic memory. Umbach G, Kantak P, Jacobs J, Kahana M, Pfeiffer BE, Sperling M, Lega B, Proc Natl Acad Sci U S A 2020 Oct Direct brain recordings identify hippocampal and cortical networks that distinguish successful versus failed episodic memory retrieval. Tan RJ, Rugg MD, Lega BC, Neuropsychologia 2020 10 147 107595 Commentary: Awake Craniotomy and Memory Induction Through Electrical Stimulation: Why Are Penfield's Findings Not Replicated in the Modern Era? Kulkarni NJ, Lega BC, Neurosurgery 2020 08 87 2 E138-E139 Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy. Nair DR, Laxer KD, Weber PB, Murro AM, Park YD, Barkley GL, Smith BJ, Gwinn RP, Doherty MJ, Noe KH, Zimmerman RS, Bergey GK, Anderson WS, Heck C, Liu CY, Lee RW, Sadler T, Duckrow RB, Hirsch LJ, Wharen RE, Tatum W, Srinivasan S, McKhann GM, Agostini MA, Alexopoulos AV, Jobst BC, Roberts DW, Salanova V, Witt TC, Cash SS, Cole AJ, Worrell GA, Lundstrom BN, Edwards JC, Halford JJ, Spencer DC, Ernst L, Skidmore CT, Sperling MR, Miller I, Geller EB, Berg MJ, Fessler AJ, Rutecki P, Goldman AM, Mizrahi EM, Gross RE, Shields DC, Schwartz TH, Labar DR, Fountain NB, Elias WJ, Olejniczak PW, Villemarette-Pittman NR, Eisenschenk S, Roper SN, Boggs JG, Courtney TA, Sun FT, Seale CG, Miller KL, Skarpaas TL, Morrell MJ, Neurology 2020 Jul The effects of direct brain stimulation in humans depend on frequency, amplitude, and white-matter proximity. Mohan UR, Watrous AJ, Miller JF, Lega BC, Sperling MR, Worrell GA, Gross RE, Zaghloul KA, Jobst BC, Davis KA, Sheth SA, Stein JM, Das SR, Gorniak R, Wanda PA, Rizzuto DS, Kahana MJ, Jacobs J, Brain Stimul 2020 May Functionally distinct high and low theta oscillations in the human hippocampus. Goyal A, Miller J, Qasim SE, Watrous AJ, Zhang H, Stein JM, Inman CS, Gross RE, Willie JT, Lega B, Lin JJ, Sharan A, Wu C, Sperling MR, Sheth SA, McKhann GM, Smith EH, Schevon C, Jacobs J, Nat Commun 2020 05 11 1 2469 Comparison of fMRI correlates of successful episodic memory encoding in temporal lobe epilepsy patients and healthy controls. Hill PF, King DR, Lega BC, Rugg MD, Neuroimage 2020 02 207 116397 Longitudinal Differences in Human Hippocampal Connectivity During Episodic Memory Processing. Choi K, Bagen L, Robinson L, Umbach G, Rugg M, Lega B, Cereb Cortex Commun 2020 1 1 tgaa010 Memory retrieval modulates spatial tuning of single neurons in the human entorhinal cortex. Qasim SE, Miller J, Inman CS, Gross RE, Willie JT, Lega B, Lin JJ, Sharan A, Wu C, Sperling MR, Sheth SA, McKhann GM, Smith EH, Schevon C, Stein JM, Jacobs J, Nat Neurosci 2019 12 22 12 2078-2086 Results 1-10 of 63 1 2 3 4 5 Next Last Professional Associations/Affiliations American Association of Neurological Surgeons (2017-2018) Cognitive Neuroscience Society (2012-2018) Congress of Neurological Surgeons (2012-2018) Society for Neuroscience (2011-2018)
