Nivedita Patni, M.D. Titles and Appointments Associate Professor Schools Medical School Departments Pediatrics You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Dr. Nivedita Patni received her medical degree from All-India Institute of Medical Sciences in India, and completed her pediatric residency at Miami Children’s Hospital before coming to UT Southwestern Medical Center for Pediatric Endocrinology fellowship. Her academic and clinical interests are pediatric endocrine and lipid disorders; including genetic dyslipidemias like type 1 hyperlipoproteinemia (T1HLP) and rare lipodystrophy and progeria syndromes; and is actively seeing all pediatric lipid disorders at Children’s Dallas. She has published about prevalence, clinical features and various etiologies of extreme hypertriglyceridemia in children; and is working on determining genetic basis of lipid disorders in children and investigating the genotype-phenotype relationships in these patients. Patients with T1HLP are a challenge to treat, and at this time, there is no specific therapy for these patients. She recently completed a pilot randomized, open label, cross over clinical trial of gastric and pancreatic lipase inhibitor, orlistat in these patients and showed promising results. She has described a novel syndrome of generalized lipodystrophy associated with pilocytic astrocytoma and novel finding of juvenile-onset generalized lipodystrophy in two patients with a new mutation in LMNA gene. She has also studied and published detailed clinical and metabolic parameters of children with FPLD-2 causing LMNA mutations and continues her research work at the Center for Human Nutrition at UT Southwestern Medical Center to understand natural history and physiology of rare lipodystrophy syndromes. Education Medical School All India Institute of Medical Sciences, India (2008) Residency Miami Children's Hospital (2013), Pediatrics Fellowship UT Southwestern/Children's Medical Center (2016), Pediatric Endocrinology Research Interest Genetic Dyslipidemia Lipodystrophy Syndromes Progeria Syndromes Type 1 Hyperlipoproteinemia Publications Novel Homozygous Variants in CIDEC and WRN in a Young Female with Lipodystrophy and Thyroid Cancer Patni N, Xing C, Huang CY, Brown RJ, Garg A International journal of molecular sciences 2026 Jan 27 Lipodystrophy Severity Score to Assess Disease Burden in Lipodystrophy Brown RJ, Akinci B, Yosef M, Phillips H, Khalatbari S, Sorkina E, Santini F, Vigouroux C, Brush M, Meral R, Ceccarini G, Zeybel M, Prodam F, Von Schnurbein J, Sorice GP, Guler MC, Patni N, Tanrikulu S, Alyaarubi S, Ozgen BS, Foss-Freitas MC, Ozisik S, Segrestin B, Ozcan B, Adiyaman SC, Musolino G, Sekizkardes H, Musso C, Lebenthal Y, Ozen S, Simha V, Simsir IY, Stears A, Scherer T, Gambineri A, Lima JG, Semple R, Wabitsch M, Araujo-Vilar D, Hegele RA, Oral EA Journal of Clinical Endocrinology and Metabolism 2025 Nov 110 3243-3255 Familial chylomicronemia syndrome: An expert clinical review from the National Lipid Association Javed F, Hegele RA, Garg A, Patni N, Gaudet D, Williams L, Khan M, Li Q, Ahmad Z Journal of Clinical Lipidology 2025 May 19 382-403 Development and validation of clinical criteria to identify familial chylomicronemia syndrome (FCS) in North America Hegele RA, Ahmad Z, Ashraf A, Baldassarra A, Brown AS, Chait A, Freedman SD, Kohn B, Miller M, Patni N, Soffer DE, Wang J, Broder MS, Chang E, Yermilov I, Campos C, Gibbs SN Journal of Clinical Lipidology 2025 Jan 19 83-94 The clinical approach to child and adolescent patients with lipodystrophy: a series of international case discussions Brown RJ, Akinci B, Al Yaarubi S, Bismuth E, Cappa M, Deeb A, Kamrath C, Musso C, Patni N, Prodam F, Williams R, Wabitsch M Frontiers in Endocrinology 2025 16 Diagnosis, treatment and management of lipodystrophy: the physician perspective on the patient journey Patni N, Chard C, Araújo-Vilar D, Phillips H, Magee DA, Akinci B Orphanet Journal of Rare Diseases 2024 Dec 19 Metabolic and other morbid complications in congenital generalized lipodystrophy type 4 Akinci G, Alyaarubi S, Patni N, Alhashmi N, Al-Shidhani A, Prodam F, Gagne N, Babalola F, Al Senani A, Muniraj K, Elsayed SM, Beghini M, Saydam BO, Allawati M, Vaishnav MS, Can E, Simsir IY, Sorkina E, Dursun F, Kamrath C, Cavdar U, Chakraborty PP, Dogan OA, Al Hosin A, Al Maimani A, Comunoglu N, Hamed A, Huseinbegovic T, Scherer T, Curtis J, Brown RJ, Topaloglu H, Simha V, Wabitsch M, Tuysuz B, Oral EA, Akinci B, Garg A American Journal of Medical Genetics, Part A 2024 Jun 194 Updates in the management of pediatric dyslipidemia Choudhari P, Patni N Current opinion in lipidology 2023 Aug 34 156-161 Therapies for Lowering Low-Density Lipoprotein Cholesterol Patni N 2023 Jan 51-61 Evaluation and Management of Lipids and Lipoproteins in Children and Adolescents Patel A, Patni N Endocrinology and Metabolism Clinics of North America 2022 Sep 51 573-588 Results 1-10 of 37 1 2 3 4 Next Last Books Featured Books Cerebrotendinous Xanthomatosis. In Diagnosis and Treatment of Lipid Disorders in Children and Adolescents in www.endotext.org. Patni N, Wilson D. (2016). South Dartmouth: MDText.com, Inc. Genetics and Dyslipidemia. In Diagnosis and Treatment of Lipid Disorders in Children and Adolescents in www.endotext.org. Patni N, Ahmad Z, Wilson D. (2016). South Dartmouth: MDText.com, Inc. Honors & Awards Pediatric Endocrine Society Travel Award for Annual Meeting (2016) Endocrine Society Early Career Forum Travel Award for Annual Meeting (2015) Travel Award for Lipodystrophy meeting: Leptin and Beyond (2014) Pediatric Endocrine Society Travel Award for Lipodystrophy Diagnosis & Treatment Consensus Statement meeting2015 Professional Associations/Affiliations Lipid Special Interest Group, Pediatric Endocrine Society (2018) National Lipid Association (2017) Pediatric Endocrinologists of Texas, Oklahoma, Louisiana, and Arkansas (2013) The Endocrine Society (2013) The Pediatric Endocrine Society (2014)
