Preethi Mani, M.D., M.P.H., FACC, is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center, and a member of its Cardiology Division. She specializes in multimodality cardiac imaging, valvular heart disease, and cardiac risk stratification.

Dr. Mani holds bachelor's degrees in cognitive science and in psychology from Case Western Reserve University in Cleveland, Ohio. She earned her medical degree at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, and completed internal medicine residency training at UT Southwestern. She then gained advanced training through fellowships in cardiology and advanced cardiac imaging at the Cleveland Clinic Foundation. She also holds a master’s degree in public health in epidemiology from the Harvard TH Chan School of Public Health in Boston, Massachusetts.

Dr. Mani is board certified in internal medicine, cardiovascular disease, nuclear medicine, and echocardiography. She is also trained in cardiovascular computed tomography (CT) and cardiac magnetic resonance imaging (MRI). She joined the UT Southwestern faculty in 2021.

She has twice received the Cleveland Clinic Educational Foundation’s Excellence in Teaching Award.


Medical School
Case Western Reserve University School of Medicine (2013)
UT Southwestern Medical Center (2016), Internal Medicine
Cleveland Clinic Foundation (2019), Cardiology
Graduate School
Harvard University School of Public Health (2021), Public Health
Cleveland Clinic Foundation (2021), Cardiac Advanced Imaging

Honors & Awards

  • Cardiology Fellows Research Competition Finalist
    Cleveland Clinic (2019)
  • Excellence in Teaching Award
    Cleveland Clinic Educational Foundation (2019)
  • Excellence in Teaching Award
    Cleveland Clinic Educational Foundation (2017)
  • Oral Presentation Award
    Irwin H. Lepow Student Research Day, Case Western Reserve University School of Medicine (2012)
  • Best Poster Award
    Cleveland Clinic Lerner Research Institute Research Day (2010)
  • Ruth L. Kirschtein National Research Service Award
    Department of Molecular Cardiology, Cleveland Clinic Foundation (2009)

Professional Associations/Affiliations

  • American College of Cardiology