Jin Choi, Ph.D.

Assistant Professor

Schools: Medical School | Graduate School
Departments: Center for Genetics of Host Defense | Immunology
Graduate Programs: Immunology

Publications

Featured Publications

Disruption of the ZFP574-THAP12 complex suppresses B cell malignancies in mice.: Zhong X, Moresco JJ, SoRelle JA, Song R, Jiang Y, Nguyen MT, Wang J, Bu CH, Moresco EMY, Beutler B, Choi JH, Proc Natl Acad Sci U S A 2024 Jul 121 31 e2409232121
Viable mutations of mouse midnolin suppress B cell malignancies.: Zhong X, Peddada N, Moresco JJ, Wang J, Jiang Y, Rios JJ, Moresco EMY, Choi JH, Beutler B, J Exp Med 2024 Jun 221 6
Essential role of MFSD1-GLMP-GIMAP5 in lymphocyte survival and liver homeostasis.: Zhong X, Moresco JJ, Diedrich JK, Pinto AM, SoRelle JA, Wang J, Keller K, Ludwig S, Moresco EMY, Beutler B, Choi JH, Proc Natl Acad Sci U S A 2023 Dec 120 50 e2314429120
OVOL2 sustains postnatal thymic epithelial cell identity.: Zhong X, Peddada N, Wang J, Moresco JJ, Zhan X, Shelton JM, SoRelle JA, Keller K, Lazaro DR, Moresco EMY, Choi JH, Beutler B, Nat Commun 2023 Nov 14 1 7786
Essential requirement for IER3IP1 in B cell development.: Zhong X, Moresco JJ, Keller K, Lazaro DR, Ely C, Moresco EMY, Beutler B, Choi JH, Proc Natl Acad Sci U S A 2023 Nov 120 46 e2312810120
RNPS1 inhibits excessive tumor necrosis factor/tumor necrosis factor receptor signaling to support hematopoiesis in mice.: Zhong X, Choi JH, Hildebrand S, Ludwig S, Wang J, Nair-Gill E, Liao TC, Moresco JJ, Liu A, Quan J, Sun Q, Zhang D, Zhan X, Choi M, Li X, Wang J, Gallagher T, Moresco EMY, Beutler B, Proc Natl Acad Sci U S A 2022 May 119 18 e2200128119
Essential cell-extrinsic requirement for PDIA6 in lymphoid and myeloid development.: Choi JH, Zhong X, Zhang Z, Su L, McAlpine W, Misawa T, Liao TC, Zhan X, Russell J, Ludwig S, Li X, Tang M, Anderton P, Moresco EMY, Beutler B, J Exp Med 2020 Apr 217 4
Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.: Zhong X, Su L, Yang Y, Nair-Gill E, Tang M, Anderton P, Li X, Wang J, Zhan X, Tomchick DR, Brautigam CA, Moresco EMY, Choi JH, Beutler B, Proc. Natl. Acad. Sci. U.S.A. 2020 Mar
Essential requirement for nicastrin in marginal zone and B-1 B cell development.: Choi JH, Han J, Theodoropoulos PC, Zhong X, Wang J, Medler D, Ludwig S, Zhan X, Li X, Tang M, Gallagher T, Yu G, Beutler B, Proc Natl Acad Sci U S A 2020 03 117 9 4894-4901
LMBR1L regulates lymphopoiesis through Wnt/?-catenin signaling.: Choi JH, Zhong X, McAlpine W, Liao TC, Zhang D, Fang B, Russell J, Ludwig S, Nair-Gill E, Zhang Z, Wang KW, Misawa T, Zhan X, Choi M, Wang T, Li X, Tang M, Sun Q, Yu L, Murray AR, Moresco EMY, Beutler B, Science 2019 05 364 6440