Skip to Main Content
Chieko Mineo, Ph.D.

Chieko Mineo, Ph.D.

Titles and Appointments

Professor

Schools
Medical School | Graduate School
Departments
Pediatrics | Cell Biology
Graduate Programs
Genetics, Development and Disease
  • Biography

    Dr. Chieko Mineo received both her B.S and Ph.D. in Pharmacology from University of Tokyo. She received post-doctoral training in Cell Biology at the University of Texas Southwestern Medical Center.

    Dr. Mineo joined the faculty in the Department of Pediatrics at the University of Texas Southwestern Medical Center in 2002. She is a member of the Integrative Biology Graduate Program in the Division of Basic Science. 

  • Education
    Undergraduate
    University of Tokyo (1982), Pharmacology
    Graduate School
    University of Tokyo (1992), Pharmacology
  • Research Interest
    • Antiphospholipid Syndrome
    • Insulin resistance and endothelial dysfunction
    • Vascular Biology and Atherosclerosis
  • Publications
    Identification of scavenger receptor BI as a scavenger of free heme that is essential for protection against hemolysis
    Ito M, Xue J, Guo L, Hao D, Wang Q, Williams AH, Zhan CG, Ji A, Shridas P, Su W, Liu S, Guo Z, Gong M, Gordon SM, Huang B, Jia J, Mineo C, Shaul PW, Li XA Nature communications 2026 Dec 17
    Enhancing Anthocyanin Bioavailability Unlocks the Cardiovascular Potential of Grape Pomace: A Review
    Ghanta CC, Thapa A, Tao Z, Rohatgi A, Mineo C, Kalbasi-Ashtari A, Pahlavani M Journal of Nutrition 2026 Oct 156
    Endothelial FOXO1 Lactylation: A New Link Between Disturbed Flow and Atherosclerosis
    Mineo C Circulation research 2026 Mar 138 e328413
    Role of the endothelial cell apolipoprotein E receptor 2 in modulating the effects of apoE3 and apoE4 on insulin blood-brain barrier transport
    Thomas P, Nguyen V, Weaver R, Hansen K, Sacharidou A, Banks WA, Mineo C, Shaul PW, Rhea EM PloS one 2026 Feb 21
    Regulation of Insulin Transcytosis Across Endothelium in Metabolic Health and Disease
    Mineo C, Shaul PW Arteriosclerosis, Thrombosis, and Vascular Biology 2026 Feb 46 e321545
    From lipoprotein metabolism to blood clotting: Highlights of the 2025 Fredrickson lipid research conference
    Smith AN, Beg MA, Hur WS, Ginsburg D, Kullo IJ, Davies SS, Tabas I, Williams JW, Mineo C, Cai B, Gupta RK, Amengual J, Schwendeman A, Graf GA, Thomas MS, Zheng Z Journal of lipid research 2026 67
    Apolipoprotein E receptor 2 in endothelium promote glucose tolerance by mediating insulin delivery to skeletal muscle
    Sacharidou A, Chambliss KL, Peng J, Tanigaki K, Islam MN, Sirsi S, Lemoff A, Hoyt K, Mineo C, Shaul PW Molecular Metabolism 2025 Nov 101
    The ACTH test fails to diagnose adrenal insufficiency and augments cytokine production in sepsis
    Hao D, Wang Q, Ito M, Xue J, Guo L, Huang B, Mineo C, Shaul PW, Li XA JCI Insight 2025 Apr 10
    27-hydroxycholesterol and endothelial cell immune memory link maternal hypercholesterolemia with atherosclerosis in the offspring: Atherogenesis
    Mineo C, Shaul PW Nature Cardiovascular Research 2025 Apr 4 350-352
    Endothelial SR-B1 is dispensable for thermogenesis but promotes selective cholesterol uptake in brown adipose tissue
    Hurkmans KM, Heine M, Rinninger F, Jaeckstein MY, Mineo C, Shaul PW, Heeren J Journal of lipid research 2025 66
  • Books

    Featured 

  • Professional Associations/Affiliations
    • American Diabetes Association (2006)
    • American Heart Association (2004)