Shin Yamazaki, Ph.D.
Professor
School Medical School
Department Neuroscience
Graduate Programs Neuroscience
Biography
1992-1993 Postdoctoral Fellow (Neuroscience): Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan. (Mentor: Shin-Ichi T Inouye, Ph.D.)
1993-1994 Postdoctoral Fellow (Neuroscience): Tokyo Metropolitan Institute for Neuroscience, Tokyo, Japan. (Mentor: Yoichiro Kuroda, Ph.D.)
1994-1996 Research Associate (Chronobiology): Department of Biology, University of Virginia, Charlottesville, VA. (Mentors: Michael Menaker, Ph.D. and Gene D Block, Ph.D.)
1996-2002 Research Scientist: Department of Biology, University of Virginia, Charlottesville,VA.
2000-2002 Center Investigator: NSF Center for Biological Timing
2002-2006 Research Assistant Professor, Department of Biological Sciences, Vanderbilt University, Nashville, TN.
2006-2013 Member of the Vanderbilt Kennedy Center for Research on Human Development
2006-2013 Research Associate Professor, Department of Biological Sciences, Vanderbilt University, Nashville, TN.
Research Interest
- Circadian Physiology
- Feeding and Light Entrainment of the Circadian System
- Live Cell/Tissue Real-Time Imaging
- Mouse Models for Human Disorders Caused by Disruption/Disorganization/Misalignment of the Circadian System
- Neural Circuit Controlling Feeding and Locomotor Activity Rhythms
- Pacemaker Coupling
Publications
Featured Publications
- Long days restore regular estrous cyclicity in mice lacking circadian rhythms.
- Nakamura TJ, Takasu NN, Sakazume S, Matsumoto Y, Kawano N, Pendergast JS, Yamazaki S, Nakamura W, Heliyon 2023 Jun 9 6 e16970
- Multiscale Time-resolved Analysis Reveals Remaining Behavioral Rhythms in Mice Without Canonical Circadian Clocks.
- Morris M, Yamazaki S, Stefanovska A, J Biol Rhythms 2022 May 7487304221087065
- Genetics and functional significance of the understudied methamphetamine sensitive circadian oscillator (MASCO).
- Taufique SKT, Ehichioya DE, Pendergast JS, Yamazaki S, F1000Res 2022 11 1018
- Peripheral Circadian Oscillators.
- Brown AJ, Pendergast JS, Yamazaki S, Yale J Biol Med 2019 Jun 92 2 327-335
- Period-independent novel circadian oscillators revealed by timed exercise and palatable meals.
- Flôres DE, Bettilyon CN, Yamazaki S Sci Rep 2016 6 21945
- Period determination in the food-entrainable and methamphetamine-sensitive circadian oscillator(s).
- Pendergast JS, Oda GA, Niswender KD, Yamazaki S Proc. Natl. Acad. Sci. U.S.A. 2012 Aug 109 35 14218-23
- Circadian-independent cell mitosis in immortalized fibroblasts.
- Yeom M, Pendergast JS, Ohmiya Y, Yamazaki S Proc. Natl. Acad. Sci. U.S.A. 2010 May 107 21 9665-70
- Entrainment of the circadian clock in the liver by feeding.
- Stokkan KA, Yamazaki S, Tei H, Sakaki Y, Menaker M Science 2001 Jan 291 5503 490-3
- Resetting central and peripheral circadian oscillators in transgenic rats.
- Yamazaki S, Numano R, Abe M, Hida A, Takahashi R, Ueda M, Block GD, Sakaki Y, Menaker M, Tei H Science 2000 Apr 288 5466 682-5
- Rhythmic properties of the hamster suprachiasmatic nucleus in vivo.
- Yamazaki S, Kerbeshian MC, Hocker CG, Block GD, Menaker M J. Neurosci. 1998 Dec 18 24 10709-23
Books
Featured Books
Extra-SCN Circadian Pacemakers.. In Biological Clocks with reference to suprachiasmatic nucleus Proceedings of the Sapporo Symposium on Biological Rhythm November 9-10, 2016. (Honma K and Honma S eds)
Pendergast JS, Yamazaki S (2017). Sapporo, Japan, Hokkaido University Press