Dr. Ayesha Zia is a pediatric hematologist at the Children's Medical Center's Hemostasis Thrombosis Center, and the University of Texas Southwestern School of Medicine. Previous NHF (National Hemophilia Foundation) clinical fellowship award recipient, her clinical/translational research interests are geared toward pediatric patients with bleeding and clotting disorders. Dr. Zia also leads the multidisciplinary “Young Women’s Blood Disorders Clinic” at Children's Medical Center, focused on improving the care of adolescent girls with menorrhagia and bleeding disorders as well as girls with thrombophilia first and only program in North Texas that specializes in the diagnosis and treatment of bleeding and clotting disorders and accompanying reproductive problems in young women. Dr. Zia has a particular interest in the use of global coagulation assays, like thromboelatography and thrombin generation, in the diagnosis and management of congenital bleeding and clotting disorders. Current projects are focused on 1) elucidating the biology of hormonal induced thrombosis and predictors of thrombosis in young girls on oral contraceptives, 2) outcomes of thrombosis in the pediatric population including recurrent thrombosis and post-thrombotic syndrome, 3) Improving diagnostic strategies and quality of life in adolescent females with menorrhagia and bleeding disorders and 4) thromboprophylaxis in pediatric patients undergoing orthopedic surgeries. Dr. Zia is also the institutional co-investigator for several clinical trials investigating new treatments in hemostasis and thrombosis, including new medications for hemophilia, von Willebrand disease, and blood clots.


Medical School
King Edward Medical University, Pakistan (2002)
University of Oklahoma Health Science Center (2007), Pediatrics
Children's Hospital of Michigan (2009), Pediatrics
Children's Hospital of Michigan (2012), Pediatric Hematology/oncology
Childrens Hospital of Michigan (2013), Pediatric Hemostasis/thrombosis


Featured Publications LegendFeatured Publications

The spectrum and severity of bleeding in adolescents with low von Willebrand factor-associated heavy menstrual bleeding.
Srivaths L, Minard CG, O'Brien SH, Wheeler AP, Mullins E, Sharma M, Sidonio R, Jain S, Zia A, Ragni MV, Kulkarni R, Dietrich JE, Kouides PA, Blood Adv 2020 07 4 13 3209-3216
Thrombin Generation in a patient with Triple Positive Antiphospholipid Syndrome Treated with Three Different Anticoagulants.
Bergstrom CP, Zia A, Sarode R, Nagalla S, Transfus. Apher. Sci. 2020 May 102815
The gut microbiome and thromboembolism.
Hasan RA, Koh AY, Zia A, Thromb Res 2020 05 189 77-87
Reduced Physical Activity Levels in Children after a First Episode of Acute Venous Thromboembolism.
Zia A, Yang Z, Zhang S, Babb T, J Pediatr 2020 04 219 229-235.e2
Team Approach: Pediatric Musculoskeletal Infection.
Dhar AV, Huang CJ, Sue PK, Patel K, Farrow-Gillespie AC, Hammer MR, Zia AN, Mittal VS, Copley LA, JBJS Rev 2020 Mar 8 3 e0121
Congenital disorders of glycosylation as an unusual cause of antithrombin deficiency and elevated thrombin generation.
Hasan R, Kayani S, Zia A, Pediatr Blood Cancer 2020 02 67 2 e28069
Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial.
Male C, Lensing AWA, Palumbo JS, Kumar R, Nurmeev I, Hege K, Bonnet D, Connor P, Hooimeijer HL, Torres M, Chan AKC, Kenet G, Holzhauer S, Santamaría A, Amedro P, Chalmers E, Simioni P, Bhat RV, Yee DL, Lvova O, Beyer-Westendorf J, Biss TT, Martinelli I, Saracco P, Peters M, Kállay K, Gauger CA, Massicotte MP, Young G, Pap AF, Majumder M, Smith WT, Heubach JF, Berkowitz SD, Thelen K, Kubitza D, Crowther M, Prins MH, Monagle P, Lancet Haematol 2020 Jan 7 1 e18-e27
Potential Undiagnosed VWD Or Other Mucocutaneous Bleeding Disorder Cases Estimated From Private Medical Insurance Claims.
Sidonio RF, Zia A, Fallaize D, J Blood Med 2020 11 1-11
Bleeding disorders in adolescents with heavy menstrual bleeding in a multicentre prospective US cohort.
Zia A, Jain S, Kouides P, Zhang S, Gao A, Salas N, Lau M, Wilson E, DeSimone N, Sarode R, Haematologica 2019 Oct
The Importance of a Standardized Screening Tool to Identify Thromboembolic Risk Factors in Pediatric Lower Extremity Arthroscopy Patients.
Ellis HB, Sabatino MJ, Clarke Z, Dennis G, Fletcher AL, Wyatt CW, Zia A, Wilson PL J Am Acad Orthop Surg 2019 Jan


Featured Books Legend Featured Books

Honors & Awards

  • CCRAC Research Award in Junior Investigator Category
  • George R. Buchanan Teaching award for excellence in Fellow Education
  • American Society of Hematology “Clinical Research Training Institute” Award
  • Wolf Zuelzer Research Award
    Award Recipient for outstanding research during pediatric Hematology/Oncology fellowship (2012)
  • Chief Fellow in Pediatric Hematology Oncology
  • National Hemophilia Foundation (NHF) Clinical Fellowship Award
    Award Recipient with $200,000 funded during award period (2011-2013)

Professional Associations/Affiliations

  • International Society on Thrombosis and Haemostasis (2014)
  • Hemostasis and Thrombosis Research Society (2011)
  • National Hemophilia Foundation (NHF) (2011)
  • American Society of Hematology (ASH) (2009)
  • American Society of Pediatric Hematology/Oncology (ASPHO) (2009)
  • Pakistan Medical and Dental Council (2002)