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Ayesha Zia, M.D.

Ayesha Zia, M.D.

Titles and Appointments

Associate Vice Chair of Clinical Research

Professor

Schools
Medical School
Departments
Pediatrics

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For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    Dr. Ayesha Zia is a pediatric hematologist at the Children's Medical Center's Hemostasis Thrombosis Center, and the University of Texas Southwestern School of Medicine. Previous NHF (National Hemophilia Foundation) clinical fellowship award recipient, her clinical/translational research interests are geared toward pediatric patients with bleeding and clotting disorders. Dr. Zia also leads the multidisciplinary “Young Women’s Blood Disorders Clinic” at Children's Medical Center, focused on improving the care of adolescent girls with menorrhagia and bleeding disorders as well as girls with thrombophilia first and only program in North Texas that specializes in the diagnosis and treatment of bleeding and clotting disorders and accompanying reproductive problems in young women. Dr. Zia has a particular interest in the use of global coagulation assays, like thromboelatography and thrombin generation, in the diagnosis and management of congenital bleeding and clotting disorders. Current projects are focused on 1) elucidating the biology of hormonal induced thrombosis and predictors of thrombosis in young girls on oral contraceptives, 2) outcomes of thrombosis in the pediatric population including recurrent thrombosis and post-thrombotic syndrome, 3) Improving diagnostic strategies and quality of life in adolescent females with menorrhagia and bleeding disorders and 4) thromboprophylaxis in pediatric patients undergoing orthopedic surgeries. Dr. Zia is also the institutional co-investigator for several clinical trials investigating new treatments in hemostasis and thrombosis, including new medications for hemophilia, von Willebrand disease, and blood clots.

  • Education
    Medical Education
    King Edward Medical University, Pakistan (2002)
    Internship
    University of Oklahoma Health Science Center (2007), Pediatrics
    Residency
    Children's Hospital of Michigan (2009), Pediatrics
    Fellowship
    Children's Hospital of Michigan (2012), Pediatric Hematology/Oncology
    Fellowship
    Childrens Hospital of Michigan (2013), Pediatric Hemostasis/Thrombosis
  • Publications
    Pediatric fibromuscular dysplasia presenting with acute right lower extremity limb ischemia requiring endovascular treatment and amputation – a case report
    Louiselle A, Hoffman O, Ludwig K, Zia A, Scheuerle A, Janjua H, Rakheja D, Dillenbeck J, Pimpalwar S, Gill C, Sanati-Mehrizy P, Hawkins RB BMC Pediatrics 2026 Dec 26
    An International Survey on the Assessment of Screening and Treatment of Thrombosis Complications in Pediatrics (ASTRO-Kids): communication from the ISTH SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis
    Cohen C, Klaassen I, Zhang S, Kumar R, Ahuja S, Goldenberg N, Rajpurkar M, Betensky M, Avila L, Zia A Journal of Thrombosis and Haemostasis 2026 Jul 24 2672-2682
    Nonextremity thrombosis sequelae in children: screening, diagnosis, and management
    Kumar R, Rodriguez V, Cohen C, Rajpurkar M, Zia A Journal of Thrombosis and Haemostasis 2026 Jun 24 2048-2060
    Thrombin Generation in Pediatric Haemophilia A Patients on Extended Half-Life FVIII versus Non-FVIII Therapies
    Garcia J, Yates SG, Sarode R, Young G, Zia A Haemophilia 2026 May 32 834-839
    Patient-parent perspectives in designing pediatric venous thromboembolism research: A qualitative study
    Fuksman A, Shliakhtsitsava K, Nguyen G, Umaretiya PJ, Stutzman S, Sida D, Rajpurkar M, Khurram F, Edwards H, Zia A Thrombosis research 2026 Apr 260
    Screening, diagnosis, and management of pediatric postthrombotic syndrome following extremity thrombosis
    Avila L, Betensky M, Klaassen I, Rajpurkar M, Zia A Journal of Thrombosis and Haemostasis 2026 Apr 24 1245-1252
    Clinically relevant outcomes for research in pediatric pulmonary embolism: communication from the ISTH SSC Subcommittee on Pediatric/Neonatal Thrombosis and Hemostasis
    Zia A, Whitworth H, Avila L, Klok FA, Alqahtani M, Gopalan D, Griffiths M, Rosovsky RP, Williams S, Babb TG, Rajpurkar M Journal of Thrombosis and Haemostasis 2026 Feb 24 766-780
    Efficacy and safety of thrombolysis for pediatric venous thromboembolism: a systematic review and meta-analysis
    Kawtharany H, Azzam M, Alkhader A, Betensky M, Hamarsha Q, Abou Zeid HK, Mansour R, Tabak C, Patel P, Baghdadi SL, Bercovitz RS, Bhat R, Biss T, Branchford BR, Brandão LR, Chan AK, Faustino EV, Jaffray J, Jones S, Kerlin BA, Kucine N, Kumar R, Male C, Pelland-Marcotte MC, Raffini L, Raulji CM, Sartain SE, Takemoto CM, Tarango C, van Ommen CH, Velez MC, Vesely SK, Wiernikowski J, Williams S, Wilson HP, Woods G, Zia A, Monagle P, Mustafa RA Blood Advances 2025 Nov 9 5512-5527
    How I treat pediatric pulmonary embolism
    Zia A, Goldenberg NA, Rajpurkar M Blood 2025 Oct 146 1643-1653
    International Perspectives on Vitamin K Deficiency Bleeding in Infants: A Cross-Sectional Questionnaire-Based Survey
    Sirachainan N, Komvilaisak P, van Ommen CH, Revel-Vilk S, Ohga S, Zia A, Ochiai M, Takahashi D, Suga S, Labarque V, Amankwah EK, Souvanlasy B, Betensky M, Chan AK, Chuansumrit A, Goldenberg N, Rajpurkar M Pediatric Blood and Cancer 2025 Oct 72
  • Books

    Featured 

  • Honors & Awards
    • CCRAC Research Award in Junior Investigator Category
      (2015-2017)
    • George R. Buchanan Teaching award for excellence in Fellow Education
      (2014)
    • American Society of Hematology “Clinical Research Training Institute” Award
      (2013)
    • Wolf Zuelzer Research Award
      Award Recipient for outstanding research during pediatric Hematology/Oncology fellowship (2012)
    • Chief Fellow in Pediatric Hematology Oncology
      (2011)
    • National Hemophilia Foundation (NHF) Clinical Fellowship Award
      Award Recipient with $200,000 funded during award period (2011-2013)
  • Professional Associations/Affiliations
    • American Society of Hematology (ASH) (2009)
    • American Society of Pediatric Hematology/Oncology (ASPHO) (2009)
    • Hemostasis and Thrombosis Research Society (2011)
    • International Society on Thrombosis and Haemostasis (2014)
    • National Hemophilia Foundation (NHF) (2011)
    • Pakistan Medical and Dental Council (2002)