Biography

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Carole Mendelson received a B.S. in Biology from the City College of New York and a Ph.D. in Zoology from Rutgers University, New Brunswick, N.J. She spent five years as a postdoctoral and then Staff Fellow at the National Institutes of Health in Bethesda, Maryland. She joined the faculty of UT Southwestern in 1978. Research in the Mendelson laboratory is focused on reproductive and perinatal biology and includes: (1) genetic and epigenetic mechanisms in the developmental, hormonal and tissue-specific regulation of the gene encoding SP-A, the major protein of pulmonary surfactant; (2) transcriptional regulation of aromatase (CYP19) gene expression in estrogen-producing tissues and in pathologic states, including endometriosis, cancer and preeclampsia; (3) regulatory mechanisms involved in maintenance of uterine quiescence during pregnancy and activation of contractile genes leading to term and pre-term labor. Dr. Mendelson’s research is funded by the National Institutes of Health and The Burroughs Wellcome Foundation. She held an NIH MERIT Award from 1998 – 2008.

Dr. Mendelson served as a member of the Board of Scientific Counselors for the National Heart, Lung and Blood Institute, NIH, chaired the Reproductive Scientist Development Program Selection Committee and was a member of the Basil O’Connor Starter Scholar Research Award Advisory Committee. She is active within The Endocrine Society (TES), in which she has chaired a number of committees and served as a member of Council and as Vice President for Basic Scientists from 2008 – 2011. She was recently elected as Presidential nominee of the Society for Reproductive Investigation and will serve as President in 2021 - 2022. She also has been active in several committees that support the career advancement of women in science and medicine. She was president of Women in Endocrinology of TES. Within UT Southwestern, she co-chairs the Women in Science and Medicine Advisory Committee.

Education

Undergraduate
City College-Cuny (1964), Biology
Graduate School
Rutgers the State University (1970), Zoology

Research Interest

  • Mechanisms in the initiation of parturition
  • Molecular mechanisms in placental development
  • Molecular Mechanisms in the developmental, hormonal and tissue-specific regulation of surfactant protein gene expression in fetal lung tissue

Publications

Featured Publications LegendFeatured Publications

Effects of epidermal growth factor and insulin-like growth factor I on the levels of mRNA encoding aromatase cytochrome P-450 of human ovarian granulosa cells.
Steinkampf MP, Mendelson CR, Simpson ER Mol. Cell. Endocrinol. 1988 Sep 59 1-2 93-9
The major apoprotein of rabbit pulmonary surfactant. Elucidation of primary sequence and cyclic AMP and developmental regulation.
Boggaram V, Qing K, Mendelson CR J. Biol. Chem. 1988 Feb 263 6 2939-47
Developmental and hormonal regulation of cholesterol side chain cleavage cytochrome P-450 in the fetal rabbit testis.
Anderson CM, Mendelson CR Mol. Cell. Endocrinol. 1988 Feb 55 2-3 121-30
Regulation of the synthesis of the major surfactant apoprotein in fetal rabbit lung tissue
Mendelson CR, Chen C, Boggaram V, Zacharias C, Snyder JM J Biol Chem 1986 261 9938-9943

Honors & Awards

  • Presidential Nominee (2019), Society for Reproductive investigation
    Officer in Scientific Society (2019-2020)
  • Sydney H. Ingbar Distinguished Service Award, The Endocrine Society
    Service Award (2019)
  • Frederick Naftolin Award for Mentorship, Society for Reproductive Investigation
    Mentorship Award (2017)
  • SGI-Pardi President's Distinguished Scientist Award, Society for Reproductive Investigation
    Award for Scientific Excellence (2014)
  • Mentor Award
    Women in Endocrinology (2010)
  • Vice-President, Basic Science
    The Endocrine Society (2008-2011)
  • Alpha Omega Alpha
    Honor Society (2002)
  • Roy O. Greep Award
    The Endocrine Society (2001)
  • NIH MERIT Award
    Regulation of SP-A Expression in Fetal Lung (1998-2008)