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James P. McCulley, M.D. was born in Fort Worth, Texas, and received a bachelor’s degree from Texas Christian University (Alpha Chi Honor Society). He graduated from Washington University School of Medicine and was a member of AOA. He subsequently did a straight medical internship on the Harvard Medical Service at Boston City Hospital prior to five years of training at the Massachusetts Eye and Ear Infirmary (MEEI), which encompassed residency as well as a corneal fellowship. He is a Diplomat of the American Board of Ophthalmology, as well as a Fellow of the Royal College of Ophthalmology (U.K.). After leaving MEEI, he spent two years on staff at Bethesda Naval Hospital prior to joining the faculty of the Department of Ophthalmology at Stanford University Medical School. He moved to Dallas on the faculty at The University of Texas, Southwestern Medical School, in 1980 and became Professor and Chairman in 1981, a position that he currently holds. He has held positions in many different organizations including the presidency of the Castroviejo Society, secretary-treasurer of the Association of University Professors of Ophthalmology, member of several medical related boards, including the Eye Bank Association of American, Contact Lens Association of Ophthalmologists, and Center for Alternatives to Animal Testing at Johns Hopkins. He has served on both NIH and FDA Advisory Committees and chaired the FDA Ophthalmic Device Panel from 1999 to 2001 and the Vision A Study Section. He continues to serve as a consultant to the FDA. He also served on the Residency Review Committee for Ophthalmology from 1990 to 1996. He has served for many years as an associate examiner for the American Board of Ophthalmology. He has held multiple administrative positions at The University of Texas Southwestern Medical School including, Chairman of the Practice Plan Committee. He has received multiple honors over the years including the Honor and Senior Honor awards from the AAO and presented more than 140 invited lectureships and visiting professorships, received the Distinguished Alumnus Award from Texas Christian University and the Distinguished Alumni Award from Harvard Medical School (formerly Massachusetts Eye & Ear Infirmary) and been recognized as one of the "Best Ophthalmologists/Doctors" in many different publications. He has been principle investigator of an NEI/NIH grant since 1978. He has published more than 200 peer reviewed manuscripts, citable abstracts, books and book chapters.


Medical School
Washington University School of Medicine (1968)
Boston City Hospital (1969), Internal Medicine
Research Fellowship
Retina Foundation (1970), Cornea Research, Department of
Massachusetts Eye and Ear Infirmary (1973), Ophthalmology
Massachusetts Eye and Ear Infirmary (1974), Cornea & External Disease
Retina Foundation (1974), Cornea Research, Department of

Research Interest

  • Acanthamoeba Keratitis
  • Chronic Blepharitis
  • Corneal transplantation
  • Severe Infectious Disease
  • Tissue culture of endothelium and epithelium


Featured Publications LegendFeatured Publications

In vitro penetration of human corneal epithelium by Acanthamoeba castellanii: a scanning and transmission electron microscopy study.
Moore MB, Ubelaker JE, Martin JH, Silvany R, Dougherty JM, Meyer DR, McCulley JP Cornea 1991 Jul 10 4 291-8
The role of cholesterol in chronic blepharitis.
Shine WE, McCulley JP Invest. Ophthalmol. Vis. Sci. 1991 Jul 32 8 2272-80
Effect of contact lens preservatives on Acanthamoeba.
Silvany RE, Dougherty JM, McCulley JP Ophthalmology 1991 Jun 98 6 854-7
The role of wax and sterol ester fatty acids in chronic blepharitis.
Dougherty JM, Osgood JK, McCulley JP Invest. Ophthalmol. Vis. Sci. 1991 May 32 6 1932-7
Scanning electron microscopy of Acanthamoeba castellanii: adherence to surfaces of new and used contact lenses and to human corneal button epithelium.
Moore MB, Ubelaker J, Silvany R, Martin J, McCulley JP Rev. Infect. Dis. 1991 Mar-Apr 13 Suppl 5 S423
Differential effect of chelation on the pH tolerance of corneal epithelium in tissue culture.
Meyer DR, McCulley JP Ophthalmic Res. 1991 23 4 204-12
In vivo and in vitro collagenolytic activity of Acanthamoeba castellanii.
He YG, Niederkorn JY, McCulley JP, Stewart GL, Meyer DR, Silvany R, Dougherty J Invest. Ophthalmol. Vis. Sci. 1990 Nov 31 11 2235-40
The effect of currently available contact lens disinfection systems on Acanthamoeba castellanii and Acanthamoeba polyphaga.
Silvany RE, Dougherty JM, McCulley JP, Wood TS, Bowman RW, Moore MB Ophthalmology 1990 Mar 97 3 286-90
A comparison between interrupted and continuous suturing techniques in keratoplasty.
Eliason JA, McCulley JP Cornea 1990 Jan 9 1 10-6
Ocular hydrofluoric acid burns: animal model, mechanism of injury and therapy.
McCulley JP Trans Am Ophthalmol Soc 1990 88 649-84

Honors & Awards

  • D Magazine
    Best Doctors in Dallas (2017)
  • Texas Monthly Magazine
    Super Doctors (2017)
  • Distinguished Service Award (Texas Ophthalmological Association)
    Highest honor bestowed by the TOA; a peer-recognized award acknowledging the recipient's lifelong dedication to ophthalmology patients and to the profession. (2016)
  • Life Achievement Award, American Academy of Ophthalmology
  • Washington University Medical Center
    Alumni Achievement Award (2008)
  • Harvard Medical School (formerly Massachusetts Eye and Ear Infirmary)
    Distinguished Alumni Award (2006)
  • TCU Alumni Association
    Distinguished Alumni Award (2001)
  • Castle Connolly
    America's Top Doctors (2001 onwards)

Professional Associations/Affiliations

  • Alpha Omega Alpha
  • American Academy of Ophthalmology
  • American College of Surgeons
  • American Medical Association
  • American Ophthalmological Society