Download Curriculum Vitae

James P. McCulley, M.D. was born in Fort Worth, Texas, and received a bachelor’s degree from Texas Christian University (Alpha Chi Honor Society). He graduated from Washington University School of Medicine and was a member of AOA. He subsequently did a straight medical internship on the Harvard Medical Service at Boston City Hospital prior to five years of training at the Massachusetts Eye and Ear Infirmary (MEEI), which encompassed residency as well as a corneal fellowship. He is a Diplomat of the American Board of Ophthalmology, as well as a Fellow of the Royal College of Ophthalmology (U.K.). After leaving MEEI, he spent two years on staff at Bethesda Naval Hospital prior to joining the faculty of the Department of Ophthalmology at Stanford University Medical School. He moved to Dallas on the faculty at The University of Texas, Southwestern Medical School, in 1980 and became Professor and Chairman in 1981, a position that he currently holds. He has held positions in many different organizations including the presidency of the Castroviejo Society, secretary-treasurer of the Association of University Professors of Ophthalmology, member of several medical related boards, including the Eye Bank Association of American, Contact Lens Association of Ophthalmologists, and Center for Alternatives to Animal Testing at Johns Hopkins. He has served on both NIH and FDA Advisory Committees and chaired the FDA Ophthalmic Device Panel from 1999 to 2001 and the Vision A Study Section. He continues to serve as a consultant to the FDA. He also served on the Residency Review Committee for Ophthalmology from 1990 to 1996. He has served for many years as an associate examiner for the American Board of Ophthalmology. He has held multiple administrative positions at The University of Texas Southwestern Medical School including, Chairman of the Practice Plan Committee. He has received multiple honors over the years including the Honor and Senior Honor awards from the AAO and presented more than 140 invited lectureships and visiting professorships, received the Distinguished Alumnus Award from Texas Christian University and the Distinguished Alumni Award from Harvard Medical School (formerly Massachusetts Eye & Ear Infirmary) and been recognized as one of the "Best Ophthalmologists/Doctors" in many different publications. He has been principle investigator of an NEI/NIH grant since 1978. He has published more than 200 peer reviewed manuscripts, citable abstracts, books and book chapters.


Medical School
Washington University School of Medicine (1968)
Boston City Hospital (1969), Internal Medicine
Research Fellowship
Retina Foundation (1970), Cornea Research, Department of
Massachusetts Eye and Ear Infirmary (1973), Ophthalmology
Massachusetts Eye and Ear Infirmary (1974), Cornea & External Disease
Retina Foundation (1974), Cornea Research, Department of

Research Interest

  • Acanthamoeba Keratitis
  • Chronic Blepharitis
  • Corneal transplantation
  • Severe Infectious Disease
  • Tissue culture of endothelium and epithelium


Featured Publications LegendFeatured Publications

Demonstration of feasibility of application of a portable keratometer to cadaveric donor corneas.
Dave AS, McCulley JP Cornea 1994 Sep 13 5 379-82
Antibody-dependent neutrophil-mediated killing of Acanthamoeba castellanii.
Stewart GL, Shupe K, Kim I, Silvany RE, Alizadeh H, McCulley JP, Niederkorn JY Int. J. Parasitol. 1994 Aug 24 5 739-42
Efficacy of lodoxamide 0.1% ophthalmic solution in resolving corneal epitheliopathy associated with vernal keratoconjunctivitis.
Santos CI, Huang AJ, Abelson MB, Foster CS, Friedlaender M, McCulley JP Am. J. Ophthalmol. 1994 Apr 117 4 488-97
Apoptosis as a mechanism of cytolysis of tumor cells by a pathogenic free-living amoeba.
Alizadeh H, Pidherney MS, McCulley JP, Niederkorn JY Infect. Immun. 1994 Apr 62 4 1298-303
Role of wax ester fatty alcohols in chronic blepharitis.
Shine WE, McCulley JP Invest. Ophthalmol. Vis. Sci. 1993 Dec 34 13 3515-21
Clinical and diagnostic use of in vivo confocal microscopy in patients with corneal disease.
Cavanagh HD, Petroll WM, Alizadeh H, He YG, McCulley JP, Jester JV Ophthalmology 1993 Oct 100 10 1444-54
In vitro and in vivo tumoricidal properties of a pathogenic/free-living amoeba.
Pidherney MS, Alizadeh H, Stewart GL, McCulley JP, Niederkorn JY Cancer Lett. 1993 Aug 72 1-2 91-8
Relation of cholesterol-stimulated Staphylococcus aureus growth to chronic blepharitis.
Shine WE, Silvany R, McCulley JP Invest. Ophthalmol. Vis. Sci. 1993 Jun 34 7 2291-6
The role of contact lenses, trauma, and Langerhans cells in a Chinese hamster model of Acanthamoeba keratitis.
van Klink F, Alizadeh H, He Y, Mellon JA, Silvany RE, McCulley JP, Niederkorn JY Invest. Ophthalmol. Vis. Sci. 1993 May 34 6 1937-44
Topical fibronectin therapy of persistent corneal epithelial defects. Fibronectin Study Group.
McCulley JP, Horowitz B, Husseini ZM, Horowitz M Trans Am Ophthalmol Soc 1993 91 367-86; discussion 386-90

Honors & Awards

  • D Magazine
    Best Doctors in Dallas (2017)
  • Texas Monthly Magazine
    Super Doctors (2017)
  • Distinguished Service Award (Texas Ophthalmological Association)
    Highest honor bestowed by the TOA; a peer-recognized award acknowledging the recipient's lifelong dedication to ophthalmology patients and to the profession. (2016)
  • Life Achievement Award, American Academy of Ophthalmology
  • Washington University Medical Center
    Alumni Achievement Award (2008)
  • Harvard Medical School (formerly Massachusetts Eye and Ear Infirmary)
    Distinguished Alumni Award (2006)
  • TCU Alumni Association
    Distinguished Alumni Award (2001)
  • Castle Connolly
    America's Top Doctors (2001 onwards)

Professional Associations/Affiliations

  • Alpha Omega Alpha
  • American Academy of Ophthalmology
  • American College of Surgeons
  • American Medical Association
  • American Ophthalmological Society