Download Curriculum Vitae

James P. McCulley, M.D. was born in Fort Worth, Texas, and received a bachelor’s degree from Texas Christian University (Alpha Chi Honor Society). He graduated from Washington University School of Medicine and was a member of AOA. He subsequently did a straight medical internship on the Harvard Medical Service at Boston City Hospital prior to five years of training at the Massachusetts Eye and Ear Infirmary (MEEI), which encompassed residency as well as a corneal fellowship. He is a Diplomat of the American Board of Ophthalmology, as well as a Fellow of the Royal College of Ophthalmology (U.K.). After leaving MEEI, he spent two years on staff at Bethesda Naval Hospital prior to joining the faculty of the Department of Ophthalmology at Stanford University Medical School. He moved to Dallas on the faculty at The University of Texas, Southwestern Medical School, in 1980 and became Professor and Chairman in 1981, a position that he currently holds. He has held positions in many different organizations including the presidency of the Castroviejo Society, secretary-treasurer of the Association of University Professors of Ophthalmology, member of several medical related boards, including the Eye Bank Association of American, Contact Lens Association of Ophthalmologists, and Center for Alternatives to Animal Testing at Johns Hopkins. He has served on both NIH and FDA Advisory Committees and chaired the FDA Ophthalmic Device Panel from 1999 to 2001 and the Vision A Study Section. He continues to serve as a consultant to the FDA. He also served on the Residency Review Committee for Ophthalmology from 1990 to 1996. He has served for many years as an associate examiner for the American Board of Ophthalmology. He has held multiple administrative positions at The University of Texas Southwestern Medical School including, Chairman of the Practice Plan Committee. He has received multiple honors over the years including the Honor and Senior Honor awards from the AAO and presented more than 140 invited lectureships and visiting professorships, received the Distinguished Alumnus Award from Texas Christian University and the Distinguished Alumni Award from Harvard Medical School (formerly Massachusetts Eye & Ear Infirmary) and been recognized as one of the "Best Ophthalmologists/Doctors" in many different publications. He has been principle investigator of an NEI/NIH grant since 1978. He has published more than 200 peer reviewed manuscripts, citable abstracts, books and book chapters.


Medical School
Washington University School of Medicine (1968)
Boston City Hospital (1969), Internal Medicine
Research Fellowship
Retina Foundation (1970), Cornea Research, Department of
Massachusetts Eye and Ear Infirmary (1973), Ophthalmology
Massachusetts Eye and Ear Infirmary (1974), Cornea & External Disease
Retina Foundation (1974), Cornea Research, Department of

Research Interest

  • Acanthamoeba Keratitis
  • Chronic Blepharitis
  • Corneal transplantation
  • Severe Infectious Disease
  • Tissue culture of endothelium and epithelium


Featured Publications LegendFeatured Publications

Keratoconjunctivitis sicca associated with meibomian secretion polar lipid abnormality.
Shine WE, McCulley JP Arch. Ophthalmol. 1998 Jul 116 7 849-52
Effectiveness of BION tears, Cellufresh, Aquasite, and Refresh Plus for moderate to severe dry eye.
Donshik PC, Nelson JD, Abelson M, McCulley JP, Beasley C, Laibovitz RA Adv. Exp. Med. Biol. 1998 438 753-60
Meibomian secretions in chronic blepharitis.
McCulley JP, Shine WE Adv. Exp. Med. Biol. 1998 438 319-26
Complications of combined radial thermokeratoplasty and incisional keratotomy.
Hargrave SL, Husseini ZM, McCulley JP CLAO J 1997 Jul 23 3 205-8
In vitro amoebicidal activity of propamidine and pentamidine isethionate against Acanthamoeba species and toxicity to corneal tissues.
Alizadeh H, Silvany RE, Meyer DR, Dougherty JM, McCulley JP Cornea 1997 Jan 16 1 94-100
A compositional based model for the tear film lipid layer.
McCulley JP, Shine W Trans Am Ophthalmol Soc 1997 95 79-88; discussion 88-93
Meibomian gland triglyceride fatty acid differences in chronic blepharitis patients.
Shine WE, McCulley JP Cornea 1996 Jul 15 4 340-6
In vivo confocal microscopy and Acanthamoeba keratitis.
Cavanagh HD, McCulley JP Am. J. Ophthalmol. 1996 Feb 121 2 207-8
Successful immunization against Acanthamoeba keratitis in a pig model.
Alizadeh H, He Y, McCulley JP, Ma D, Stewart GL, Via M, Haehling E, Niederkorn JY Cornea 1995 Mar 14 2 180-6
Acanthamoeba keratitis.
McCulley JP, Alizadeh H, Niederkorn JY CLAO J 1995 Jan 21 1 73-6

Honors & Awards

  • D Magazine
    Best Doctors in Dallas (2017)
  • Texas Monthly Magazine
    Super Doctors (2017)
  • Distinguished Service Award (Texas Ophthalmological Association)
    Highest honor bestowed by the TOA; a peer-recognized award acknowledging the recipient's lifelong dedication to ophthalmology patients and to the profession. (2016)
  • Life Achievement Award, American Academy of Ophthalmology
  • Washington University Medical Center
    Alumni Achievement Award (2008)
  • Harvard Medical School (formerly Massachusetts Eye and Ear Infirmary)
    Distinguished Alumni Award (2006)
  • TCU Alumni Association
    Distinguished Alumni Award (2001)
  • Castle Connolly
    America's Top Doctors (2001 onwards)

Professional Associations/Affiliations

  • Alpha Omega Alpha
  • American Academy of Ophthalmology
  • American College of Surgeons
  • American Medical Association
  • American Ophthalmological Society