Dr. Mayo obtained her B.A. degree in Psychology from Northwestern University; Evanston, Illinois in 1986. She obtained her M.D. degree from Baylor College of Medicine; Houston, Texas in 1990. After her internship and residency in Internal Medicine at University of California, Irvine, California (1990-1993), she completed a fellowship in Gastroenterology/Hepatology at the University of Texas Southwestern Medical Center at Dallas, Texas (1993-1996). Dr. Mayo specializes in the diagnosis and management of acute and chronic liver diseases, and she enjoys establishing a friendly and supportive relationship with her patients. Dr. Mayo has a keen interest in immune-mediated and cholestatic liver diseases such as primary biliary cirrhosis, autoimmune hepatitis, and primary sclerosing cholangitis. She also has a special interest in the management of itching from liver disease.  Dr. Mayo also conducts clinical trials investigating new treatments for primary biliary cirrhosis, primary sclerosing cholangitis, fatty liver, autoimmune hepatitis, and hepatorenal syndrome. 


Medical School
Baylor College of Medicine (1990)
University of California, Irvine (1991), Internal Medicine
University of California, Irvine (1993), Internal Medicine
UT Southwestern Medical Center (1996), Gastroenterology

Research Interest

  • Autoimmune liver diseases
  • Liver Disease in Pregnancy
  • Primary biliary cirrhosis


Featured Publications LegendFeatured Publications

Primary biliary cirrhosis in monozygotic and dizygotic twins: genetics, epigenetics, and environment
Selmi C, Mayo MJ, Bach M, Ishibashi H, Invernizzi P, Gish RG, Gordon SC, Wright H, Zweiban B, Podda M, Gerswhin ME Gastroenterology 2004 127 485-492
Long-term efficacy of sertraline as a treatment for cholestatic pruritus in patients with primary biliary cirrhosis.
Browning J, Combes B, Mayo MJ Am. J. Gastroenterol. 2003 Dec 98 12 2736-41
Primary biliary cirrhosis: the future.
Mayo MJ Clin Liver Dis 2003 Nov 7 4 957-69
Extrahepatic manifestations of hepatitis C infection.
Mayo MJ Am. J. Med. Sci. 2003 Mar 325 3 135-48
Exercise-induced weight loss preferentially reduces abdominal fat.
Mayo MJ, Grantham JR, Balasekaran G Med Sci Sports Exerc 2003 Feb 35 2 207-13
PBC: The future
Mayo MJ Clin Liv Dis 2003 7 957-969
Primary Biliary Cirrhosis
Mayo MJ, Saboorian H, Thiele DL Atlas of Gastroenterology 2003 3rd edition 2374-2387
Extrahepatic manifestations of hepatitis C
Mayo MJ American Journal of Medical Sciences 2003 325 135-148
Long term efficacy of sertraline: as a treatment for cholestatic pruritus
Browning J, Combes B, Mayo MJ Am J Gastroenterol 2003 98 2736-2741
Similar T-cell oligoclonality in antimitochondrial antibody-positive and -negative primary biliary cirrhosis.
Mayo MJ, Lipsky PE, Miller SN, Stastny P, Combes B Dig. Dis. Sci. 2001 Feb 46 2 345-51


Featured Books Legend Featured Books

Honors & Awards

  • D Magazine Best Doctors, Hepatology
    Peer-nominated top 5 Hepatologists in the Dallas-Forth Worth area (2010-2016)

Professional Associations/Affiliations

  • American Association for the Study of Liver Diseases (AASLD)
  • American Gastroenterological Association (AGA)
  • Anerican College of Gastroenterology(ACG)
  • European Association for the Study of Liver Diseases (EASL)