Dr. Mayo obtained her B.A. degree in Psychology from Northwestern University; Evanston, Illinois in 1986. She obtained her M.D. degree from Baylor College of Medicine; Houston, Texas in 1990. After her internship and residency in Internal Medicine at University of California, Irvine, California (1990-1993), she completed a fellowship in Gastroenterology/Hepatology at the University of Texas Southwestern Medical Center at Dallas, Texas (1993-1996). Dr. Mayo specializes in the diagnosis and management of acute and chronic liver diseases, and she enjoys establishing a friendly and supportive relationship with her patients. Dr. Mayo has a keen interest in immune-mediated and cholestatic liver diseases such as primary biliary cirrhosis, autoimmune hepatitis, and primary sclerosing cholangitis. She also has a special interest in the management of itching from liver disease.  Dr. Mayo also conducts clinical trials investigating new treatments for primary biliary cirrhosis, primary sclerosing cholangitis, fatty liver, autoimmune hepatitis, and hepatorenal syndrome. 


Medical School
Baylor College of Medicine (1990)
University of California, Irvine (1991), Internal Medicine
University of California, Irvine (1993), Internal Medicine
UT Southwestern Medical Center (1996), Gastroenterology

Research Interest

  • Autoimmune liver diseases
  • Liver Disease in Pregnancy
  • Primary biliary cholangitis
  • primary sclerosing cholangitis


Featured Publications LegendFeatured Publications

Diagnosis and management of autoimmune hepatitis in adults and children: 2019 practice guidance and guidelines from the American Association for the study of liver diseases.
Mack CL, Adams D, Assis DN, Kerkar N, Manns MP, Mayo MJ, Vierling JM, Alsawas M, Murad MH, Czaja AJ, Hepatology 2019 Dec
A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis.
Mayo MJ, Pockros PJ, Jones D, Bowlus CL, Levy C, Patanwala I, Bacon B, Luketic V, Vuppalanchi R, Medendorp S, Dorenbaum A, Kennedy C, Novak P, Gu J, Apostol G, Hirschfield GM, Hepatol Commun 2019 Mar 3 3 365-381
Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases.
Lindor KD, Bowlus CL, Boyer J, Levy C, Mayo M, Hepatology 2019 01 69 1 394-419


Featured Books Legend Featured Books

Honors & Awards

  • Lyman Bihartz Teaching Award
    Fellow- Nominated Teacher of the Year (2018)
  • D Magazine Best Doctors
    Peer Nominated Award of Excellence in Clinical Care (2015-2019)

Professional Associations/Affiliations

  • European Association for the Study of Liver Diseases (EASL) (2005)
  • Anerican College of Gastroenterology(ACG) (1994)
  • American Association for the Study of Liver Diseases (AASLD) (1993)