Marlyn Mayo, M.D. Titles and Appointments Professor School Medical School Department Internal Medicine You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Marlyn Mayo, M.D., is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of the Division of Digestive and Liver Diseases. She specializes in the diagnosis and management of acute and chronic liver diseases and has a keen interest in immune-mediated and cholestatic liver diseases such as primary biliary cirrhosis, autoimmune hepatitis, and primary sclerosing cholangitis. Originally from Syracuse, New York, Dr. Mayo holds a bachelor's degree in psychology from Northwestern University in Evanston, Illinois. She obtained her medical degree from Baylor College of Medicine in Houston and completed internal medicine residency training at the University of California-Irvine. She then received advanced training through a fellowship program in gastroenterology and hepatology at UT Southwestern. Certified by the American Board of Internal Medicine in gastroenterology, Dr. Mayo joined the UT Southwestern faculty in 1996. Dr. Mayo came to UT Southwestern to do research and work on the largest PBC trial at the time with Burton Combes, M.D., who started the liver unit at UT Southwestern. Later, Dr. Mayo worked with Peter Lipsky, M.D., to conduct translational research on immune targets in PBC. From there, she started to investigate other autoimmune and cholestatic liver diseases. Dr. Mayo's research focuses on clinical trials investigating new treatments for primary biliary cirrhosis, primary sclerosing cholangitis, and autoimmune hepatitis. She has a specific interest in cholestatic itching, and has also actively studied hepatorenal syndrome and liver diseases of pregnancy. Dr. Mayo has been involved in setting the standards for medical education. She has been both the Associate Program Director and Program Director of the Gastroenterology Fellowship program at UT Southwestern. Dr. Mayo is a member of several professional societies, including the American Association for the Study of Liver Diseases, the American Gastroenterological Association, the Texas Medical Association, the Dallas County Medical Society, and the American College of Gastroenterology. She has served on multiple committees for the AASLD in the areas of research and education. Dr. Mayo has been included in D Magazine's Best Doctors list on numerous occasions. Education Medical School Baylor College of Medicine (1990) Internship University of California, Irvine (1991), Internal Medicine Residency University of California, Irvine (1993), Internal Medicine Fellowship UT Southwestern Medical Center (1996), Gastroenterology Research Interest Autoimmune liver diseases Liver Disease in Pregnancy Primary biliary cholangitis primary sclerosing cholangitis Publications Featured Publications Updated Etiology and Significance of Elevated Bilirubin During Pregnancy: Changes Parallel Shift in Demographics and Vaccination Status. Duraiswamy S, Sheffield JS, Mcintire D, Leveno K, Mayo MJ Dig. Dis. Sci. 2016 Sep Predicting Outcomes of Primary Biliary Cholangitis Using the GLOBE Score. Mayo MJ Gastroenterol Hepatol (N Y) 2015 Dec 11 12 842-4 Development of a Successful Scholarly Activity and Research Program for Subspecialty Trainees. Mayo MJ, Rockey DC Am. J. Med. Sci. 2015 May American Association for the Study of Liver Diseases endpoints conference: design and endpoints for clinical trials in primary biliary cirrhosis. Silveira MG, Brunt EM, Heathcote J, Gores GJ, Lindor KD, Mayo MJ Hepatology 2010 Jul 52 1 349-59 The 5-D itch scale: a new measure of pruritus. Elman S, Hynan LS, Gabriel V, Mayo MJ Br. J. Dermatol. 2010 Mar 162 3 587-93 Prediction of clinical outcomes in primary biliary cirrhosis by serum enhanced liver fibrosis assay. Mayo MJ, Parkes J, Adams-Huet B, Combes B, Mills AS, Markin RS, Rubin R, Wheeler D, Contos M, West AB, Saldana S, Getachew Y, Butsch R, Luketic V, Peters M, Di Bisceglie A, Bass N, Lake J, Boyer T, Martinez E, Boyer J, Garcia-Tsao G, Barnes D, Rosenberg WM Hepatology 2008 Nov 48 5 1549-57 Sertraline as a first-line treatment for cholestatic pruritus. Mayo MJ, Handem I, Saldana S, Jacobe H, Getachew Y, Rush AJ Hepatology 2007 Mar 45 3 666-74 A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis. Hirschfield GM, Bowlus CL, Mayo MJ, Kremer AE, Vierling JM, Kowdley KV, Levy C, Villamil A, Ladrón de Guevara Cetina AL, Janczewska E, Zigmond E, Jeong SH, Yilmaz Y, Kallis Y, Corpechot C, Buggisch P, Invernizzi P, Londoño Hurtado MC, Bergheanu S, Yang K, Choi YJ, Crittenden DB, McWherter CA, N Engl J Med 2024 Feb 390 9 783-794 Seladelpar treatment reduces interleukin-31 and pruritus in patients with primary biliary cholangitis. Kremer AE, Mayo MJ, Hirschfield GM, Levy C, Bowlus CL, Jones DE, Johnson JD, McWherter CA, Choi YJ, Hepatology 2023 Dec Efficacy and Safety of Elafibranor in Primary Biliary Cholangitis. Kowdley KV, Bowlus CL, Levy C, Akarca US, Alvares-da-Silva MR, Andreone P, Arrese M, Corpechot C, Francque SM, Heneghan MA, Invernizzi P, Jones D, Kruger FC, Lawitz E, Mayo MJ, Shiffman ML, Swain MG, Valera JM, Vargas V, Vierling JM, Villamil A, Addy C, Dietrich J, Germain JM, Mazain S, Rafailovic D, Taddé B, Miller B, Shu J, Zein CO, Schattenberg JM, N Engl J Med 2023 Nov Results 1-10 of 51 1 2 3 4 5 Next Last Books Featured Books Primary Biliary Cirrhosis. In Yamada's Atlas of Gastroenterology, 7th edition Mayo MJ, (2020). Wily Blackwell Primary Biliary Cirrhosis. In Yamada's Textbook of Gastroenterology, 8th edition Mayo MJ (2020). Wily Blackwell Complications of Cholestasis. In Cholestatic Liver Disease 2nd edition Ahmed A and Mayo MJ (2014). Humana Press Budd-Chiari Syndrome, Portal Vein Thrombosis and Other Vascular Disorders of the Liver.. In Handbook of Liver Diseases Mayo MJ and Mitchell MC (2016). Honors & Awards Education Excellence AwardUT Southwestern Graduate Medical Education Office (2020) Graduate Medical Education Excellence AwardUT Southwestern Medical Center (2020) Lyman Bihartz Teaching AwardFellow- Nominated Teacher of the Year (2018) D Magazine Best DoctorsPeer Nominated Award of Excellence in Clinical Care (2015-2024) Independent Investigator AwardPfizer Pharmaceuticals (2002) Liver Scholar AwardAmerican Liver Foundation (1996) Alumni Award in NeurologyBaylor College of Medicine (1989) Professional Associations/Affiliations American Association for the Study of Liver Diseases (1993) American College of Gastroenterology (2014) American Gastroenterological Association (1993) Dallas County Medical Society (1993) European Association for the Study of Liver Diseases (2013) Texas Medical Association (1993)
