Darin Okuda, M.D. Titles and Appointments Professor School Medical School Department Neurology You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Darin T. Okuda, M.D., is a Professor in the Department of Neurology at UT Southwestern Medical Center. He is a clinician-scientist specializing in multiple sclerosis and other demyelinating disorders of the central nervous system. Dr. Okuda serves as Director of the Neuroinnovation Program and Multiple Sclerosis and Neuroimmunology Imaging Program. Research: Dr. Okuda’s is nationally and internationally recognized for his recent work in defining and investigating the radiologically isolated syndrome. His current research focuses on creating next generation healthcare by designing innovative connections between patients and providers, developing new diagnostic and clinical surveillance metrics, and transforming medical decision-making. He is actively involved in end-to-end dynamic approaches for the design, creation, and implementation of extreme healthcare concepts aimed at delivering care more accurately, efficiently, and intelligently. Dr. Okuda’s work has been published in the Annals of Neurology, Neurology, Human Molecular Genetics, Brain, Journal of NeuroImaging, Proceedings of the National American Academy of Sciences, and Science. Affiliations: Dr. Okuda is a Diplomate of the American Board of Psychiatry and Neurology Inc., a Fellow of the American Academy of Neurology, a Fellow of the American Neurological Association, and a member of the American Academy of Neurology Committees on Neuroimaging and Ethics. Background: Born and raised in Hawaii, Dr. Okuda earned his undergraduate, graduate, and medical degrees at the University of Hawaii. He completed his residency training in neurology at the Barrow Neurological Institute and performed his fellowship in neuroimmunology at the University of California-San Francisco Multiple Sclerosis Center. Education Medical School University of Hawaii at Manoa John A. Burns School of Medicine (2000) Internship St. Joseph's Hospital & Medical Center (2001), Internal Medicine Residency St. Joseph's Hospital & Med. Ctr. (2004), Neurology Fellowship UCSF Multiple Sclerosis Center (2006), Neuroimmunology Research Interest 3-Dimensional conformational metrics Artificial intelligence Multiple sclerosis Myelin oligodendrocyte glycoprotein antibody-associated disease Neuroimaging Neuromyelitis optica spectrum disorder Radiologically isolated syndrome Software development Publications Dynamic Expansion and Contraction of Multiple Sclerosis T2-Weighted Hyperintense Lesions Are Present below the Threshold of Visual Perception Okuda DT, Moog TM, McCreary M, Shan K, Zubkow K, Newton BD, Smith AD, Patel MA, Burgess KW, Lebrun-Frénay C American Journal of Neuroradiology 2025 Feb 46 443-450 Analysis of healthcare utilization before the diagnosis of radiologically isolated syndrome Lebrun-Frenay C, Kerbrat S, Okuda DT, Landes-Chateau C, Kantarci OH, Pierret C, Drezen E, Nowak E, Siva A, Azevedo CJ, Cohen M, Leray E Multiple Sclerosis Journal 2025 Feb 31 184-196 Faster and better than a physician?: Assessing diagnostic proficiency of ChatGPT in misdiagnosed individuals with neuromyelitis optica spectrum disorder Shan K, Patel MA, McCreary M, Punnen TG, Villalobos F, Tardo LM, Horton LA, Sguigna PV, Blackburn KM, Munoz SB, Burgess KW, Moog TM, Smith AD, Okuda DT Journal of the Neurological Sciences 2025 Jan 468 Transforming grayscale MRI images to color utilizing generative artificial intelligence to better understand multiple sclerosis Okuda DT, Lebrun-Frénay C Journal of Central Nervous System Disease 2025 Jan 17 Time to move past typical syndromes in the diagnosis of multiple sclerosis Lebrun-Frenay C, Okuda DT Multiple Sclerosis Journal 2024 Oct 30 1570-1572 Dimethyl fumarate preserves brainstem and cervical spinal cord integrity in radiologically isolated syndrome Author Collaboration ob, Okuda DT, Azevedo CJ, Pelletier D, Moog TM, Moazami S, Rezvani S, Bovis F, Sormani MP, Siva A, Kantarci O, Lebrun-Frénay C, Vargas WS, Stüve O, Repovic P, Pardo G, Okuda DT, Okai A, Naismith RT, Mowry EM, Hua LH, Donlon S, Azevedo CJ, Amezcua L Journal of neurology 2024 Sep 271 5899-5910 Underdosed generic specialty medications: A prescription for patient harm? Okuda DT, Burgess KW, Moog TM, Patel MA Multiple Sclerosis and Related Disorders 2024 Aug 88 The diagnostic workup of children with the radiologically isolated syndrome differs by age and by sex Author Collaboration ob, Makhani N, Lebrun-Frenay C, Siva A, Shabanova V, Wassmer E, Santoro JD, Narula S, Brenton JN, Mar S, Durand-Dubief F, Zephir H, Mathey G, Rojas JI, de Seze J, Tenembaum S, Stone RT, Casez O, Carra-Dallière C, Neuteboom RF, Ahsan N, Arroyo HA, Cabre P, Gombolay G, Inglese M, Louapre C, Margoni M, Palavra F, Pohl D, Reich DS, Ruet A, Thouvenot E, Timby N, Tintore M, Uygunoglu U, Vargas W, Venkateswaran S, Verhelst H, Wickstrom R, Azevedo CJ, Kantarci O, Shapiro ED, Okuda DT, Pelletier D Journal of neurology 2024 Jul 271 4019-4027 Radiologically isolated syndrome in the spectrum of multiple sclerosis Okuda DT Multiple Sclerosis Journal 2024 May 30 630-636 The diagnostic value of the central vein sign in radiologically isolated syndrome Landes-Chateau C, Levraut M, Okuda DT, Themelin A, Cohen M, Kantarci OH, Siva A, Pelletier D, Mondot L, Lebrun-Frenay C Annals of Clinical and Translational Neurology 2024 Mar 11 662-672 Results 1-10 of 127 1 2 3 4 5 Next Last Books Featured Books Contemporary Topics in Multiple Sclerosis. In Neurologic Clinics, Multiple Sclerosis Okuda, DT (Ed.) (2018). Primary Angiitis of the Central Nervous System. In MR Imaging in White Matter Disease of the Brain and Spinal Cord Okuda DT, Vollmer TL (2006). Enough of the Fear: An Insider's Guide to Understanding, Managing, and Living Well with Multiple Sclerosis Wright, K, Winkler M, Okuda DT (2019). Radiologically Isolated Syndrome: MR Imaging Features Suggestive of Multiple Sclerosis Prior to First Symptom Onset. In Advances in Imaging of Multiple Sclerosis Okuda, DT (2017). Immunosuppressive Treatments in Multiple Sclerosis. In Handbook of Clinical Neurology, Multiple Sclerosis and Related Disorders Okuda, DT (2014). Honors & Awards Mimics Innovation Award 2020North and South America Finalist (2020) STRATASYS Neuroscience Innovation AwardAdvancing neuroscience through the study of changes in 3-dimensional conformation (2020) Alpha Omega Alpha Honor Medical Society (2019) American Academy of Neurology, Brainstorm: A Competition for the Innovator in All of Us, Grand Prize WinnerInnovation Award (2018) International Congress on Advanced Treatments & Technologies in Multiple SclerosisBest Abstract Award (2018) Merck KGaA: Multiple Sclerosis Innovation AwardAward for 3-dimensional modeling in multiple sclerosis (2018) Reality Science: DeeperMind Innovation AwardInnovative approach towards understanding MS through augmented reality (2018) Alpha Omega Alpha Honor Medical Society Research FellowshipResearch fellow within the field of vascular surgery (1997) Professional Associations/Affiliations American Society of Neuroimaging (2008) Fellow, American Academy of Neurology (2014) Fellow, American Neurological Association (2014) Fellow, British Medical Journal (2009) New York Academy of Sciences (2016)
