Helmut Kramer, Ph.D. Professor School Medical School Department Neuroscience | Cell Biology Graduate Programs Genetics, Development and Disease, Neuroscience Biography In 1989, Dr. Krämer completed his Ph.D. at the University of Cologne, Germany, where he worked with Dr. Benno Mülller-Hill on DNA looping in the lac operon. As a postdoctoral fellow in the lab of Dr. Larry Zipursky at UCLA, he studied cell-cell interactions during neuronal differentiation in the compound eye of Drosophila. In 1993, he joined UT Southwestern Medical Center at Dallas as an Assistant Professor in Cell Biology and Neuroscience. Education Graduate School Cologne University (1989), Genetics Research Interest Cell signaling in the Drosophila eye Drosophila genetics Endocytic trafficking in development Membrane trafficking and autophagy Publications Featured Publications Allnighter pseudokinase-mediated feedback links proteostasis and sleep in Drosophila. Shekhar S, Moehlman AT, Park B, Ewnetu M, Tracy C, Titos I, Pawlowski K, Tagliabracci VS, Krämer H, Nat Commun 2023 May 14 1 2932 A phosphoswitch at acinus-serine437 controls autophagic responses to cadmium exposure and neurodegenerative stress. Nandi N, Zaidi Z, Tracy C, Krämer H, Elife 2022 Jan 11 Yorkie Growth-Promoting Activity Is Limited by Atg1-Mediated Phosphorylation. Tyra LK, Nandi N, Tracy C, Krämer H, Dev. Cell 2020 Feb Adaptation to constant light requires Fic-mediated AMPylation of BiP to protect against reversible photoreceptor degeneration. Moehlman AT, Casey AK, Servage K, Orth K, Krämer H Elife 2018 Jul 7 Stress-induced Cdk5 activity enhances cytoprotective basal autophagy in Drosophila melanogaster by phosphorylating acinus at serine437. Nandi N, Tyra LK, Stenesen D, Krämer H Elife 2017 Dec 6 ARC Syndrome-Linked Vps33B Protein Is Required for Inflammatory Endosomal Maturation and Signal Termination. Akbar MA, Mandraju R, Tracy C, Hu W, Pasare C, Krämer H Immunity 2016 Aug STING controls energy stress-induced autophagy and energy metabolism via STX17. Rong Y, Zhang S, Nandi N, Wu Z, Li L, Liu Y, Wei Y, Zhao Y, Yuan W, Zhou C, Xiao G, Levine B, Yan N, Mou S, Deng L, Tang Z, Liu X, Kramer H, Zhong Q, J Cell Biol 2022 Jul 221 7 Autophagy Keeps the Balance in Tissue Homeostasis. Buszczak M, Krämer H, Dev. Cell 2019 May 49 4 499-500 Drosophila p53 directs non-apoptotic programs in postmitotic tissue. Kurtz P, Jones AE, Tiwari B, Link N, Wylie A, Tracy C, Krämer H, Abrams JM Mol. Biol. Cell 2019 Mar mbcE18120791 The glial sodium-potassium-2-chloride cotransporter is required for synaptic transmission in the Drosophila visual system. Stenesen D, Moehlman AT, Schellinger JN, Rodan AR, Krämer H Sci Rep 2019 Feb 9 1 2475 Results 1-10 of 42 1 2 3 4 5 Next Last Honors & Awards American Cancer Society Postdoctoral Fellowship (1991) EMBO Long Term Fellowship (1989) Predoctoral Fellowship in the Fritz-Thyssen-Graduierten-Kolleg (1985)
