Zengfu Shang, Ph.D.

Assistant Professor

School: Medical School
Department: Radiation Oncology

Education

Undergraduate: Central China Normal Univ (2004), Biotechnology
Graduate School: Beijing Inst of Radiation Med (2009), Biochemistry

Publications

NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT: Wu Z, Nguyen PT, Sondhi V, Yao RW, Lu Z, Dai T, Chiang JC, Cai F, Williams IM, Blatt EB, Shang Z, Cai L, Zhang J, Moore MD, Alshamleh I, Li X, Ogu T, Zacharias LG, Winston R, Patricio JS, Johnson X, Chen WM, Cong Q, Mathews TP, Zhang Y, Zhang L, DeBerardinis RJ Science 2025 Dec 390 1134-1142
Nuclear DAB2IP regulates DNA replication initiation through activating PLK1-mediated HBO1 phosphorylation: Shang ZF, Yu L, Newman C, Chen WM, Birdsong GW, Sharp BC, Story MD, Saha D, Davis AJ Nucleic acids research 2025 Nov 53
Lipoylation inhibition enhances radiation control of lung cancer by suppressing homologous recombination DNA damage repair: Chiang JC, Shang Z, Rosales T, Cai L, Chen WM, Cai F, Vu H, Minna JD, Ni M, Davis AJ, Timmerman RD, DeBerardinis RJ, Zhang Y Science Advances 2025 Mar 11
PDLIM1 sustains DNA damage response by promoting chromatin relaxation and activating DNA–PK complex: Lang Y, Gao D, Yu L, Zhang XX, Saha D, Chen BP, Gu MM, Shang ZF Genes and Diseases 2024 Nov 11
Polymerase iota (POLI) confers radioresistance of esophageal squamous cell carcinoma by regulating RAD51 stability and facilitating homologous recombination: Li X, Gao D, Shen F, Chen H, Zhang Z, He C, Gao A, Lang Y, Zhu X, Zhou J, Shang ZF, Ding WQ, Zhu J Cell Death Discovery 2023 Dec 9
Corrigendum to “The vanillin derivative VND3207 protects intestine against radiation injury by modulating p53/NOXA signaling pathway and restoring the balance of gut microbiota” [Free Radic. Biol. Med. 145 (2019) 223–236/ PMID: 31580946; DOI: 10.1016/j.freeradbiomed.2019.09.035, (S0891584919313942), (10.1016/j.freeradbiomed.2019.09.035)]: Li M, Gu MM, Lang Y, Shi J, Chen BP, Guan H, Yu L, Zhou PK, Shang ZF Free Radical Biology and Medicine 2023 Aug 204 83
Nanodrugs with intrinsic radioprotective exertion: Turning the double-edged sword into a single-edged knife: Guo J, Zhao Z, Shang ZF, Tang Z, Zhu H, Zhang K Exploration 2023 Apr 3
Correction: TAB182 aggravates progression of esophageal squamous cell carcinoma by enhancing β-catenin nuclear translocation through FHL2 dependent manner (Cell Death & Disease, (2022), 13, 10, (900), 10.1038/s41419-022-05334-2): Gao A, Su Z, Shang Z, He C, Miao D, Li X, Zou S, Ding W, Zhou Y, Sun M, Zhou J Cell Death and Disease 2023 Apr 14
DNA-PKcs and ATM modulate mitochondrial ADP-ATP exchange as an oxidative stress checkpoint mechanism: Chen WM, Chiang JC, Shang Z, Palchik G, Newman C, Zhang Y, Davis AJ, Lee H, Chen BP EMBO Journal 2023 Mar 42
PIG3 downregulation enhances the radiosensitivity of NSCLC cells by promoting G₂/M cell cycle arrest and apoptosis: Zhou H, Tang L, Shang ZF, Zhou PK, Li M Radiation Medicine and Protection 2023 Mar 4 19-25