Andrew Lemoff, Ph.D.

 Featured Publications

PTH/PTHrP Receptor Signaling Restricts Arterial Fibrosis in Diabetic LDLR-/- Mice by Inhibiting Myocardin-Related Transcription Factor Relays

Abraham Behrmann, Dalian Zhong, Li Li, Su-Li Cheng, Megan Mead, Bindu Ramachandran, Parastoo Sabaeifard, Mohammad Goodarzi, Andrew Lemoff, Henry M. Kronenberg, Dwight A. Towler Circulation Research 2020 126 1363-1378

Yeast Ataxin-2 Forms an Intracellular Condensate Required for the Inhibition of TORC1 Signaling during Respiratory Growth.

Yang YS, Kato M, Wu X, Litsios A, Sutter BM, Wang Y, Hsu CH, Wood NE, Lemoff A, Mirzaei H, Heinemann M, Tu BP, Cell 2019 Apr 177 3 697-710.e17

Improved strategy for isoleucine 1H/13C methyl labeling in Pichia pastoris

Rustam Ali, Lindsay D. Clark, Jacob A. Zahm, Andrew Lemoff, Karthik Ramesh, Daniel M. Rosenbaum & Michael K. Rosen Journal of Biomolecular NMR 2019 73 687?697

A dual regulatory circuit consisting of S-adenosylmethionine decarboxylase protein and its reaction product controls expression of the paralogous activator prozyme in Trypanosoma brucei.

Patel MM, Volkov OA, Leija C, Lemoff A, Phillips MA PLoS Pathog. 2018 Oct 14 10 e1007404

A GTPase-activating protein binding protein (G3BP1) / antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells.

Ramachandran B, Stabley JN, Cheng SL, Behrmann AS, Gay A, Li L, Mead M, Kozlitina J, Lemoff A, Mirzaei H, Chen Z, Towler DA J. Biol. Chem. 2018 Apr

Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells.

Kalantari R, Hicks JA, Li L, Gagnon KT, Sridhara V, Lemoff A, Mirzaei H, Corey DR RNA 2016 May

Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase.

Theodoropoulos PC, Gonzales SS, Winterton SE, Rodriguez-Navas C, McKnight JS, Morlock LK, Hanson JM, Cross B, Owen AE, Duan Y, Moreno JR, Lemoff A, Mirzaei H, Posner BA, Williams NS, Ready JM, Nijhawan D Nat. Chem. Biol. 2016 Feb

Optimization of a Novel Series of Ataxia-Telangiectasia Mutated (ATM) Kinase Inhibitors as Potential Radiosensitizing Agents.

Min J, Guo K, Suryadevara PK, Zhu F, Holbrook G, Chen Y, Feau C, Young BM, Lemoff A, Connelly MC, Kastan MB, Guy RK J. Med. Chem. 2015 Dec

Fucosylation and protein glycosylation create functional receptors for cholera toxin.

Wands AM, Fujita A, McCombs JE, Cervin J, Dedic B, Rodriguez AC, Nischan N, Bond MR, Mettlen M, Trudgian DC, Lemoff A, Quiding-Järbrink M, Gustavsson B, Steentoft C, Clausen H, Mirzaei H, Teneberg S, Yrlid U, Kohler JJ Elife 2015 Oct 4

Detection of FGF15 in Plasma by Stable Isotope Standards and Capture by Anti-peptide Antibodies and Targeted Mass Spectrometry.

Katafuchi T, Esterházy D, Lemoff A, Ding X, Sondhi V, Kliewer SA, Mirzaei H, Mangelsdorf DJ Cell Metab. 2015 Jun 21 6 898-904