Biography

Dr. Mir grew up in beautiful valley of Kashmir, which is located between the Great Himalayas and the Pir Panchal Range in the Indian subcontinent. He is a graduate of Government Medical College in Kashmir, India. He completed his internship and pediatric residency at the Oklahoma University Children's Hospital, Oklahoma City. He then obtained his training in Neonatal-Perinatal Medicine at UT Southwestern. After completing his Neonatal-Perinatal Medicine fellowship in 2015, he was recruited as faculty member in the division of Neonatal-Perinatal Medicine at UT Southwestern Medical School, where he is currently working as an Associate Professor of Pediatrics, and the Program Director for the Neonatal-Perinatal Fellowship Training Program.

Dr. Mir’s primary research focus is to understand the role of placental biology in neonatal morbidities. He has made several key observations including the placental contributions to neurodevelopmental outcomes after birth asphyxia and the role of placenta in clearance of fetal inflammatory responses. He has also studied the impact of multiple placental pathologic lesions with autism spectrum disorders in extremely preterm infants, thus shedding light on possible intrauterine risk factors with increased incidence of autism spectrum disorders in these vulnerable infants. He reported the placental clearance of neurobiomarker, GFAP, and showed for the first time that episodic hypoxia during normal labor can elicit the release of GFAP.

When he’s not working, he enjoys listening to semi-classical Indian music and spending time with his wife and two children. In addition to English, Dr. Mir speaks Kashmiri, Hindi and Urdu.

Education

Medical School
Government Medical College, India (2003)
Residency
University of Oklahoma Health Sciences Center (2012), Pediatrics
Fellowship
UT Southwestern Medical Center/ Children's Medical Center (2015), Neonatal-perinatal Medicine

Research Interest

  • Birth asphyxia and neontal encephalopathy
  • Placental biology and neonatal morbidities, particularly neonatal brain injury

Publications

Featured Publications LegendFeatured Publications

Association between decreased cord blood inter-alpha inhibitor levels and neonatal encephalopathy at birth.
Bitar L, Stonestreet BS, Lim YP, Qiu J, Chen X, Mir IN, Chalak LF, Early Hum Dev 2024 May 193 106036
Postnatal Cerebral Hemodynamics and Placental Vascular Malperfusion Lesions in Neonates With Congenital Heart Disease.
Leon RL, Bitar L, Sharma K, Mir IN, Chalak LF, Pediatr Neurol 2024 Apr 156 72-78
Development of a prediction model for surgery or early mortality at the time of initial assessment for necrotizing enterocolitis.
Nayak SP, Sanchez-Rosado M, Reis JD, Brown LS, Mangona KL, Sharma P, Nelson DB, Wyckoff MH, Pandya S, Mir IN, Brion L, Am J Perinatol 2024 Jan
Impact of fetal inflammatory response on the severity of necrotizing enterocolitis in preterm infants.
Mir IN, Sánchez-Rosado M, Reis J, Uddin N, Brown LS, Mangona KL, Nelson D, Wyckoff M, Nayak SP, Brion L, Pediatr Res 2023 Dec
Impact of maternal infection on outcomes in extremely preterm infants.
Herrera CL, Kadari PS, Pruszynski JE, Mir I, Pediatr Res 2023 Nov
Risk Factors for Admission Hyperthermia and Associated Outcomes in Preterm Infants.
Chiu M, Mir I, Adhikari E, Heyne R, Ornelas N, Tolentino-Plata K, Thomas A, Burchfield P, Simcik V, Ramon E, Brown LS, Nelson DB, Wyckoff MH, Kakkilaya V, J Pediatr 2023 Nov 113842
Correlation of placental pathology with the postoperative outcomes and white matter injury in preterm infants following necrotizing enterocolitis.
Garg PM, Paschal JL, Ansari MAY, Ware J, Adams K, Taylor C, Reddy K, Rosenfeld CR, Mir IN, J Neonatal Perinatal Med 2023 Feb
Editorial: Advances and perspectives in neuroplacentology.
Vacher CM, Bonnin A, Mir IN, Penn AA, Front Endocrinol (Lausanne) 2023 14 1206072
Placental pathology associated with lenticulostriate vasculopathy (LSV) in preterm infants.
Sisman J, Leon RL, Payton BW, Brown LS, Mir IN, J Perinatol 2022 Nov
Association of Placental Pathologic Findings with the Severity of Necrotizing Enterocolitis in Preterm infants - A Matched Case-Control Study.
Garg PM, Paschal JL, Ansari MAY, Billington L, Ware J, Adams K, Hamda YA, Oshunbade A, Rosenfeld CR, Mir IN, Fetal Pediatr Pathol 2022 Aug 1-11

Books

Featured Books Legend Featured Books

Honors & Awards

  • APP Physician Partner Award from Parkland Health System
    (2023)
  • CCRAC Research Award
    Children's Clinical Research Advisory Committee (CCRAC), Children's Health Foundation (2020)
  • Travel Grant Award by International Pediatric Research Foundation
    (2020)
  • Early Career Investigator (ECI) Award
    (2019)
  • Nominated for Rising Star Clinical Excellence Award at UT Southwestern Medical Center.
    (2018)
  • Selected for 26th Annual NICHD Young Investigators Conference
    (2014)
  • Travel Award
    AAP SCCPR Conference (2014)

Professional Associations/Affiliations

  • AAP, Section on Perinatal Pediatrics (2012)
  • American Academy of Pediatrics (2009)
  • Newborn Brain Society (2020)
  • Perinatal Research Society (2019)
  • Society for Pediatric Research (2020)