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Dr. Olga Gupta, M.D., received her undergraduate degree in Biomedical Engineering from Duke University, and her medical degree from the University of California San Francisco, followed by residency training in Pediatrics at Duke University, and a fellowship in Pediatric Endocrinology at the Children’s Hospital of Philadelphia. She joined the faculty of the University of Massachusetts Medical School in 2007 then moved to the University of Texas Southwestern in 2012.  She was appointed the Medical Director of the pediatric Center for Obesity And Consequences of Health clinic in 2016.  Under her leadership the COACH program is building an interdisciplinary team of pediatric subspecialists (endocrinology, cardiology, gastroenterology), nutritionists, physical therapists, social workers, behavioral psychologists and bariatric surgeons to create a comprehensive and productive environment to care for this vulnerable patient population.

The central goals of Dr. Gupta’s research are to better understand the psychosocial mechanisms leading to poor adherence to diabetes self-management tasks in young individuals with type 1 diabetes mellitus, and to develop novel behavioral interventions that are safe and effective for this population.  Her recent publications on this topic revealed a clinically and statistically significant change in HbA1c at 3 months for the adolescent participants who received the intervention (a pet fish with instructions for pairing fish care with diabetes self-management tasks) compared with their peers in the control group (usual care).  (Maranda et al., The Diabetes Educator, 2015).  This work was featured on an NIH podcast and in the New York Times Well Section. She also demonstrated that youth who actively care for at least one household pet were 2.5 times more likely to have good glycemic control compared to children who didn’t care for a pet (Maranda and Gupta, PLoS ONE, 2016).   Dr. Gupta has a firm commitment to serving pediatric patients with diabetes and through her research she strives to have a positive impact on the health of this population. 


Medical School
University of California, San Francisco (2000)
Duke University Medical Center (2003), Pediatrics
Children's Hospital of Philadelphia (2006), Pediatric Endocrinology
Graduate School
University of Massachusetts Medical School (2010), Clinical Investigation
Other Post Graduate Training
University of Massachusetts Medical School (2010)

Research Interest

  • Diabetes in adolescents
  • Severe obesity in youth
  • Type 1 diabetes in youth
  • Type 2 diabetes in youth


Featured Publications LegendFeatured Publications

Do Atypical Antipsychotic Agents Trigger Autoimmune Diabetes?
Nwosu, Benjamin U. MD; Hardy, Olga T. MD; Angelescu, Amanda MD; Soyka, Leslie A. MD; Lee, Mary M. MD The Endocrinologist 2009 19 2 85-87
Long-term non-surgical therapy of severe persistent congenital hyperinsulinism with glucagon.
Mohnike K, Blankenstein O, Pfuetzner A, Pötzsch S, Schober E, Steiner S, Hardy OT, Grimberg A, van Waarde WM Horm. Res. 2008 70 1 59-64
Multifetal Pregnancy May Increase the Risk for Severe Maternal and Neonatal Vitamin D Deficiency
Nwosu, Benjamin U. MD; Soyka, Leslie A. MD; Angelescu, Amanda MD; Hardy, Olga T. MD; Lee, Mary M. MD The Endocrinologist 2008 18 4 172-175
Accuracy of [18F]fluorodopa positron emission tomography for diagnosing and localizing focal congenital hyperinsulinism.
Hardy OT, Hernandez-Pampaloni M, Saffer JR, Scheuermann JS, Ernst LM, Freifelder R, Zhuang H, MacMullen C, Becker S, Adzick NS, Divgi C, Alavi A, Stanley CA J. Clin. Endocrinol. Metab. 2007 Dec 92 12 4706-11
Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha.
Gupta RK, Gao N, Gorski RK, White P, Hardy OT, Rafiq K, Brestelli JE, Chen G, Stoeckert CJ, Kaestner KH Genes Dev. 2007 Apr 21 7 756-69
Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents.
Hardy OT, Hohmeier HE, Becker TC, Manduchi E, Doliba NM, Gupta RK, White P, Stoeckert CJ, Matschinsky FM, Newgard CB, Kaestner KH Mol. Endocrinol. 2007 Mar 21 3 765-73
Diagnosis and localization of focal congenital hyperinsulinism by 18F-fluorodopa PET scan.
Hardy OT, Hernandez-Pampaloni M, Saffer JR, Suchi M, Ruchelli E, Zhuang H, Ganguly A, Freifelder R, Adzick NS, Alavi A, Stanley CA J. Pediatr. 2007 Feb 150 2 140-5
PTU-associated vasculitis in a girl with Turner Syndrome and Graves' disease.
Hardy OT, Smolinski KN, Yan AC, Grimberg A Pediatr Emerg Care 2006 Jan 22 1 52-4


Featured Books Legend Featured Books

Premature Thelarche. In The 5-Minute Pediatric Consult, 4th Edition, M. Schwartz, L. Bell Jr, P. Bingham, E. Chung, D. Friedman, A. Mulberg, R. Tanel, eds.

Hardy O, Kelly A. (2005). Philadelphia, PA, Lippincott Williams & Wilkins.

Hyperinsulinism of Infancy: Localization of Focal Forms. In Pediatric PET Imaging, M. Charron, ed.

Hardy O, Stanley C. (2006). New York, Springer

Honors & Awards

  • Leadership Emerging in Academic Departments
    UT Southwestern Medical Center (2015)
  • Dedman Family Scholar in Clinical Care
  • Translational Medicine and Science Retreat
    Poster Award (2010-2011)
  • Best Paper Published from 2008's "Novel Insights from Clinical Practice"
    Hormone Research (2009)
  • Outstanding Patient-Oriented Research Poster
    Institute for Diabetes, Obesity and Metabolism Spring Symposium and Kroc Lecture (2006)
  • First Place Poster
    National Cooperative Growth Study, Genentech (2005)
  • Research Fellowship Grant
    Lawson Wilkins Pediatric Endocrine Society (2005-2006)

Professional Associations/Affiliations

  • Behavioral Research in Diabetes Group Exchange (2013)
  • American Association of Clinical Endocrinologists (2003-2006)
  • American Diabetes Association (2003)
  • Pediatric Endocrinology Society (2003)
  • The Endocrine Society (2003)
  • American Academy of Pediatrics (2000-2003)