Michael Jessen, M.D.

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Michael E. Jessen, M.D., is a Professor at UT Southwestern Medical Center and Chair of its Department of Cardiovascular and Thoracic Surgery. He holds the Frank M. Ryburn, Jr., Distinguished Chair in Cardiothoracic Surgery and Transplantion.

Originally from Canada, Dr. Jessen earned his medical degree from the University of Manitoba School of Medicine in Winnipeg, Canada, where he also completed general surgery residency training, followed by a research fellowship through the Canadian Heart Foundation, and thoracic surgery residency training at Duke University Medical Center.

Dr. Jessen's lab has received funding from the National Institutes of Health, the American Heart Association, and the Texas Advanced Technology Program. His research examines myocardial metabolism, the effects of cardiopulmonary bypass and a novel technique for long-term cardiac preservation for transplantation.

Dr. Jessen's research has yielded a broad array of publications including the Lyndon Baines Johnson Research Award of the Texas Affiliate of the American Heart Association.

Dr. Jessen has an active clinical practice that focuses on cardiac surgery, surgical electrophysiology, aortic surgery, and cardiac transplantation.

He joined the faculty of UT Southwestern in 1990.

Medical School

University of Manitoba (1981)

Internship

University of Manitoba (1982), Surgery

Residency

University of Manitoba (1986), General Surgery

Fellowship

Duke University Hospital (1988), Research

Residency

Duke University Hospital (1990), Thoracic Surgery

• Biocompatibility of materials for cardiopulmonary bypass and effects of the inflammatory response to extracorporeal circulation
• Dynamic organ preservation with continuous perfusion
• Metabolic mechanisms of myocardial protection and the effects of substrate modifications on organ protective strategies

Featured Publications

Impact of recipient age and procedure type on survival following lung transplantation for interstitial pulmonary fibrosis

Meyer DM, Edwards LB, Torres F, Jessen ME, Novik RJ Ann Thorac Surg 2005 79 950-0

Myocardial oxygen demand and redox state affect fatty acid oxidation in the potassium arrested heart

Peltz M, He TT, Adams GA, Chao RY, Jessen ME Surgery 2004 136 150-159

Antifibrinolytic Therapy During Cardiopulmonary Bypass Reduces Proinflammatory cytokine levels: A randomized, double-blind placebo-controlled study of e-Aminocaproic acid and aprotinin

Greilich PE, Brouse CF, Whitten CW, Chi L, DiMaio JM, Jessen ME J Thorac Cardiovasc Surg 2003 126 1498-1503

Extracorporeal Life Support

Meyer DM, Jessen ME 2001

Effects of amino acids on substrate selection, anaplerosis and left ventricular function in the ischemic reperfused rat heart

Jessen ME, Kovarik TE, Jeffrey FM, Sherry AD, Storey CJ, Chao RY, Ring WS, Malloy CR J Clinical Invest Spring 1993 92 831-839

Perfusion preservation vs. static preservation for cardiac transplantation: Effects on myocardial function and metabolism

Rosenbaum DH, Peltz M, DiMaio JM, Meyer DM, Wait MA, Merritt ME, Brown R, Chao RY, Ring WS, Jessen ME Journal of Heart Lung Transplantation 2008 Volume 27 93-99

Benefits of perfusion preservation in canine hearts stored for short intervals.

Rosenbaum, DH, Peltz, M, Merritt, ME, Thatcher, JE, Sasaki, H, Jessen, ME J Surg Research 2007 140 243-249

Hypothermic circulatory arrest for repair of injuries of the thoracic aorta and great vessels

Peltz M, Douglass D, Meyer DM, Wait MA, DiMaio JM, Ring WS, Jessen ME Interact Cardiovasc Thorac Surg 2006 5 560-565

Pyruvate-modified Perfadex improves lung function after long-term hypothermic storage

Peltz M He TT, Adams GA, Chao RY, Jessen ME, Meyer DM J Heart Lung Transplantation 2005 24 896-903

Perfusion preservation maintains myocardial ATP levels and reduces apoptosis in an ex-vivo rat heart transplantation model

Peltz M, He TT, Adams GA, Koshy S, Burgess SC, Chao RY, Meyer DM, Jessen ME Surgery 2005 138 795-805

• Lyndon Baines Johnson Research Award
  American Heart Association, Texas Affiliate (1994)
• Harold Micay Surgical Resident Award
  University of Manitoba (1985)
• Davis and Geck Surgical Resident Award
  University of Manitoba (1984)
• Maxwell Rady Scholarship
  University of Manitoba (1977)
• Isbister Scholarship
  University of Manitoba (1976)

• American Association for Thoracic Surgery
• American Heart Association, Council on Cardiothoracic and Vascular Surgery
• Royal College of Physicians and Surgeons of Canada
• Society of Thoracic Surgeons
• Thoracic Surgery Directors Association