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Michael E. Jessen, M.D., is a Professor at UT Southwestern Medical Center and Chair of its Department of Cardiovascular and Thoracic Surgery. He holds the Frank M. Ryburn, Jr., Distinguished Chair in Cardiothoracic Surgery and Transplantion.

Originally from Canada, Dr. Jessen earned his medical degree from the University of Manitoba School of Medicine in Winnipeg, Canada, where he also completed general surgery residency training, followed by a research fellowship through the Canadian Heart Foundation, and thoracic surgery residency training at Duke University Medical Center.

Dr. Jessen's lab has received funding from the National Institutes of Health, the American Heart Association, and the Texas Advanced Technology Program. His research examines myocardial metabolism, the effects of cardiopulmonary bypass and a novel technique for long-term cardiac preservation for transplantation.

Dr. Jessen's research has yielded a broad array of publications including the Lyndon Baines Johnson Research Award of the Texas Affiliate of the American Heart Association.

Dr. Jessen has an active clinical practice that focuses on cardiac surgery, surgical electrophysiology, aortic surgery, and cardiac transplantation.

He joined the faculty of UT Southwestern in 1990.


Medical School
University of Manitoba (1981)
University of Manitoba (1982), Surgery
University of Manitoba (1986), General Surgery
Duke University Hospital (1988), Research
Duke University Hospital (1990), Thoracic Surgery

Research Interest

  • Biocompatibility of materials for cardiopulmonary bypass and effects of the inflammatory response to extracorporeal circulation
  • Dynamic organ preservation with continuous perfusion
  • Metabolic mechanisms of myocardial protection and the effects of substrate modifications on organ protective strategies


Featured Publications LegendFeatured Publications

Perfusion preservation vs. static preservation for cardiac transplantation: Effects on myocardial function and metabolism
Rosenbaum DH, Peltz M, DiMaio JM, Meyer DM, Wait MA, Merritt ME, Brown R, Chao RY, Ring WS, Jessen ME Journal of Heart Lung Transplantation 2008 Volume 27 93-99
Benefits of perfusion preservation in canine hearts stored for short intervals.
Rosenbaum, DH, Peltz, M, Merritt, ME, Thatcher, JE, Sasaki, H, Jessen, ME J Surg Research 2007 140 243-249
Hypothermic circulatory arrest for repair of injuries of the thoracic aorta and great vessels
Peltz M, Douglass D, Meyer DM, Wait MA, DiMaio JM, Ring WS, Jessen ME Interact Cardiovasc Thorac Surg 2006 5 560-565
Pyruvate-modified Perfadex improves lung function after long-term hypothermic storage
Peltz M He TT, Adams GA, Chao RY, Jessen ME, Meyer DM J Heart Lung Transplantation 2005 24 896-903
Perfusion preservation maintains myocardial ATP levels and reduces apoptosis in an ex-vivo rat heart transplantation model
Peltz M, He TT, Adams GA, Koshy S, Burgess SC, Chao RY, Meyer DM, Jessen ME Surgery 2005 138 795-805

Honors & Awards

  • Lyndon Baines Johnson Research Award
    American Heart Association, Texas Affiliate (1994)
  • Harold Micay Surgical Resident Award
    University of Manitoba (1985)
  • Davis and Geck Surgical Resident Award
    University of Manitoba (1984)
  • Maxwell Rady Scholarship
    University of Manitoba (1977)
  • Isbister Scholarship
    University of Manitoba (1976)

Professional Associations/Affiliations

  • American Association for Thoracic Surgery
  • American Heart Association, Council on Cardiothoracic and Vascular Surgery
  • Royal College of Physicians and Surgeons of Canada
  • Society of Thoracic Surgeons
  • Thoracic Surgery Directors Association