Richard T. "Tyler" Miller, M.D., is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center and Vice Chair of the VA North Texas Health Care System.

Dr. Miller earned his medical degree from Case Western Reserve University Medical School in 1980 and was an intern, resident, chief resident, and nephrology fellow at the University of California San Francisco. 

Dr. Miller has been a deputy and associate editor for the Journal of the American Society of Nephrology, and he served on the editorial board of the American Journal of Physiology. He has been a member of the American Heart Association, VA, and NIH study sections.

His research interests include the regulation of epithelial electrolyte transport and the biophysical properties of normal and diseased renal tissues, especially glomeruli.

Research Interest

  • Biophysical properties of renal tissues
  • Regulation of renal epithelial transport by G protein-dependent signaling systems (calcium sensing receptor)


Featured Publications LegendFeatured Publications

Biophysical properties of normal and diseased renal glomeruli.
Wyss HM, Henderson JM, Byfield FJ, Bruggeman LA, Ding Y, Huang C, Suh JH, Franke T, Mele E, Pollak MR, Miner JH, Janmey PA, Weitz DA, Miller RT Am. J. Physiol., Cell Physiol. 2011 Mar 300 3 C397-405
Mechanisms of mechanical signaling in development and disease.
Janmey PA, Miller RT J. Cell. Sci. 2011 Jan 124 Pt 1 9-18
Calcium-sensing receptor decreases cell surface expression of the inwardly rectifying K+ channel Kir4.1.
Cha SK, Huang C, Ding Y, Qi X, Huang CL, Miller RT J. Biol. Chem. 2011 Jan 286 3 1828-35
Absence of filamin A prevents cells from responding to stiffness gradients on gels coated with collagen but not fibronectin.
Byfield FJ, Wen Q, Levental I, Nordstrom K, Arratia PE, Miller RT, Janmey PA Biophys. J. 2009 Jun 96 12 5095-102
Interaction of the Ca2+-sensing receptor with the inwardly rectifying potassium channels Kir4.1 and Kir4.2 results in inhibition of channel function.
Huang C, Sindic A, Hill CE, Hujer KM, Chan KW, Sassen M, Wu Z, Kurachi Y, Nielsen S, Romero MF, Miller RT Am. J. Physiol. Renal Physiol. 2007 Mar 292 3 F1073-81


Featured Books Legend Featured Books

Honors & Awards

  • Alpha Omega Alpha
    Member (1979)

Professional Associations/Affiliations

  • American Heart Association Kidney Counsel (1990)
  • American Physiologic Society (1985)
  • American Society of Nephrology (1984)
  • International Society of Nephrology (1995)