Erdal Toprak received his Ph.D. in Computational Biology and Biophysics in 2007 from the University of Illinois at Urbana-Champaign where he studied motility mechanisms of molecular motor proteins with Paul R. Selvin. He then moved to Roy Kishony's Lab at Harvard Medical School as a postdoctoral research fellow and studied evolution of antibiotic resistance.

Research Interest

  • Antibiotic Resistance and Sensitivity
  • Single Molecule Biophysics
  • Synthetic Biology


Featured Publications LegendFeatured Publications

Fluidic and microfluidic tools for quantitative systems biology.
Okumus B, Yildiz S, Toprak E Curr. Opin. Biotechnol. 2014 Feb 25 30-8
Building a morbidostat: an automated continuous-culture device for studying bacterial drug resistance under dynamically sustained drug inhibition.
Toprak E, Veres A, Yildiz S, Pedraza JM, Chait R, Paulsson J, Kishony R Nat Protoc 2013 Mar 8 3 555-67
Super-accuracy and super-resolution getting around the diffraction limit.
Toprak E, Kural C, Selvin PR Meth. Enzymol. 2010 475 1-26
Myosin VI undergoes a 180 degrees power stroke implying an uncoupling of the front lever arm.
Reifenberger JG, Toprak E, Kim H, Safer D, Sweeney HL, Selvin PR Proc. Natl. Acad. Sci. U.S.A. 2009 Oct 106 43 18255-60
Why kinesin is so processive.
Toprak E, Yildiz A, Hoffman MT, Rosenfeld SS, Selvin PR Proc. Natl. Acad. Sci. U.S.A. 2009 Aug 106 31 12717-22
Three-dimensional particle tracking via bifocal imaging.
Toprak E, Balci H, Blehm BH, Selvin PR Nano Lett. 2007 Jul 7 7 2043-5
Single-molecule fluorescence to study molecular motors.
Park H, Toprak E, Selvin PR Q. Rev. Biophys. 2007 Feb 40 1 87-111
New fluorescent tools for watching nanometer-scale conformational changes of single molecules.
Toprak E, Selvin PR Annu Rev Biophys Biomol Struct 2007 36 349-69

Honors & Awards

  • Southwestern Medical Foundation Scholar in Biomedical Research
  • EMBO Installation Grant
  • Human Frontiers Science Program Research Grant
  • The Young Scientist Award by the Turkish Academy of Sciences (TÜBA)
  • Marie Curie Career Integration Grant (CIG)
  • Eugene Rabinowitch Graduate Fellowship
  • UIUC "Teachers Ranked Excellent by Their Students"