Biography

Download Curriculum Vitae

Hao Zhu earned his bachelor’s degree in biology from Duke University, followed by an M.D. from Harvard Medical School and MIT. He underwent training in internal medicine at University of California, San Francisco and medical oncology at the Dana-Farber Cancer Institute. From 2008 to 2012, Dr. Zhu performed postdoctoral research at Boston Children’s Hospital, where he explored connections among RNA biology, cancer and regeneration in mouse models. In 2012, he joined the faculty of UT Southwestern and the Children’s Medical Center Research Institute (CRI) at UT Southwestern. He is also an attending physician in the Multidisciplinary Liver Cancer Clinic at Parkland Memorial Hospital.

Dr. Zhu is the recipient of a Burroughs Wellcome Career Award for Medical Scientists (2012), a CPRIT Scholar Award (2012) and a Stand Up To Cancer Innovative Research Grant (2016).

The Zhu laboratory is interested in understanding the relationship between injury, regeneration, and cancer. They are focused on identifying the genes and mechanisms that regulate regenerative capacity in the liver and understanding how these contribute to hepatocellular carcinoma development – the third leading cause of cancer death in the world.

 Zhu Laboratory

Education

Medical School
Harvard Medical School (2005)
Residency
University of California, San Francisco (2007), Internal Medicine
Fellowship
Dana-Farber Cancer Institute (2011), Hematology Oncology

Research Interest

  • Epigenetics
  • Liver cancer
  • Mechanisms of organ regeneration
  • RNA biology

Publications

Featured Publications LegendFeatured Publications

Arid1a loss drives non-alcoholic steatohepatitis in mice via epigenetic dysregulation of hepatic lipogenesis and fatty acid oxidation.
Moore A, Wu L, Chuang JC, Sun X, Luo X, Gopal P, Li L, Celen C, Zimmer M, Zhu H Hepatology 2018 Dec
restrains pancreatic neoplasia formation.
Wang SC, Nassour I, Xiao S, Zhang S, Luo X, Lee J, Li L, Sun X, Nguyen LH, Chuang JC, Peng L, Daigle S, Shen J, Zhu H Gut 2018 Oct
Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment.
Zhu H, Celen C, Chuang JC, Luo X, Nijem N, Walker AK, Chen F, Zhang S, Chung AS, Nguyen LH, Nassour I, Budhipramono A, Sun X, Bok LA, McEntagart M, Gevers E, Birnbaum SG, Eisch AJ, Powell CM, Ge WP, Santen GW, Chahrour M Elife 2017 Jul 6

Honors & Awards

  • Member of the American Society of Clinical Investigation
    (2018)
  • SU2C Innovative Research Grant
    (2016-2019)
  • Burroughs Wellcome Fund Career Award for Medical Scientists
    (2012)
  • CPRIT Scholar in Cancer Research
    (2012)
  • Magna cum laude and James Tolbert Shipley Prize for MD Honors Thesis, Harvard Medical School
    (2005)