Download Curriculum Vitae

Hao Zhu earned his bachelor’s degree in biology from Duke University, followed by an M.D. from Harvard Medical School and MIT. He underwent training in internal medicine at University of California, San Francisco and medical oncology at the Dana-Farber Cancer Institute. From 2008 to 2012, Dr. Zhu performed postdoctoral research at Boston Children’s Hospital, where he explored connections among RNA biology, cancer and regeneration in mouse models. In 2012, he joined the faculty of UT Southwestern and the Children’s Medical Center Research Institute (CRI) at UT Southwestern. He is also an attending physician in the Multidisciplinary Liver Cancer Clinic at Parkland Memorial Hospital.

Dr. Zhu is the recipient of a Burroughs Wellcome Career Award for Medical Scientists (2012), a CPRIT Scholar Award (2012) and a Stand Up To Cancer Innovative Research Grant (2016).

The Zhu laboratory is interested in understanding the relationship between injury, regeneration, and cancer. They are focused on identifying the genes and mechanisms that regulate regenerative capacity in the liver and understanding how these contribute to hepatocellular carcinoma development – the third leading cause of cancer death in the world.

 Zhu Laboratory


Medical School
Harvard Medical School (2005)
University of California, San Francisco (2007), Internal Medicine
Dana-Farber Cancer Institute (2011), Hematology Oncology

Research Interest

  • Epigenetics
  • Liver cancer
  • Mechanisms of organ regeneration
  • RNA biology


Featured Publications LegendFeatured Publications

Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA.
Miller JB, Zhang S, Kos P, Xiong H, Zhou K, Perelman SS, Zhu H, Siegwart DJ Angew. Chem. Int. Ed. Engl. 2016 Dec

Honors & Awards

  • Member of the American Society of Clinical Investigation
  • SU2C Innovative Research Grant
  • Burroughs Wellcome Fund Career Award for Medical Scientists
  • CPRIT Scholar in Cancer Research
  • Magna cum laude and James Tolbert Shipley Prize for MD Honors Thesis, Harvard Medical School