Khuloud Jaqaman, Ph.D. Associate Professor Endowed Title Deborah and W.A. "Tex" Moncrief, Jr. Scholar in Medical Research School Medical School Department Biophysics | Lyda Hill Department of Bioinformatics Graduate Programs Biomedical Engineering, Molecular Biophysics Biography Education and Training: B. Sc. (summa cum laude), Physics, Birzeit University, 1994-1998 Ph. D., Biophysics, Indiana University Bloomington, 1998-2003 Postdoctoral fellow, Cell Biology, The Scripps Research Institute, 2003-2009 Previous Positions: Instructor, Systems Biology, Harvard Medical School, 2009-2012 Research Interest Biology: Spatiotemporal organization of signaling proteins in the plasma membrane; mechanics-signaling cross-talk. Technology: High- and super-resolution microscopy; computer vision; stochastic mathematical modeling. Publications Featured Publications Heterogeneity in VEGF Receptor-2 Mobility and Organization on the Endothelial Cell Surface Leads to Diverse Models of Activation by VEGF. da Rocha-Azevedo B, Lee S, Dasgupta A, Vega AR, de Oliveira LR, Kim T, Kittisopikul M, Malik ZA, Jaqaman K, Cell Rep 2020 Sep 32 13 108187 Adaptive Multi-Orientation Resolution Analysis of Complex Filamentous Network Images. Kittisopikul M, Vahabikashi A, Shimi T, Goldman RD, Jaqaman K, Bioinformatics 2020 Jul FISIK: Framework for the Inference of In Situ Interaction Kinetics from Single-Molecule Imaging Data. de Oliveira LR, Jaqaman K, Biophys J 2019 09 117 6 1012-1028 A composition-dependent molecular clutch between T cell signaling condensates and actin. Ditlev JA, Vega AR, Köster DV, Su X, Tani T, Lakoduk AM, Vale RD, Mayor S, Jaqaman K, Rosen MK, Elife 2019 Jul 8 Computational analyses reveal spatial relationships between nuclear pore complexes and specific lamins. Kittisopikul M, Shimi T, Tatli M, Tran JR, Zheng Y, Medalia O, Jaqaman K, Adam SA, Goldman RD, J Cell Biol 2021 Apr 220 4 Biomolecular condensates in membrane receptor signaling. Jaqaman K, Ditlev JA, Curr Opin Cell Biol 2021 Apr 69 48-54 Single-molecule FRET imaging of GPCR dimers in living cells. Asher WB, Geggier P, Holsey MD, Gilmore GT, Pati AK, Meszaros J, Terry DS, Mathiasen S, Kaliszewski MJ, McCauley MD, Govindaraju A, Zhou Z, Harikumar KG, Jaqaman K, Miller LJ, Smith AW, Blanchard SC, Javitch JA, Nat Methods 2021 04 18 4 397-405 Stabilization of Endothelial Receptor Arrays by a Polarized Spectrin Cytoskeleton Facilitates Rolling and Adhesion of Leukocytes. Mylvaganam S, Riedl M, Vega A, Collins RF, Jaqaman K, Grinstein S, Freeman SA, Cell Rep 2020 Jun 31 12 107798 Kinesin-dependent transport of keratin filaments: a unified mechanism for intermediate filament transport. Robert A, Tian P, Adam SA, Kittisopikul M, Jaqaman K, Goldman RD, Gelfand VI FASEB J. 2018 Jun fj201800604R Multistep Track Segmentation and Motion Classification for Transient Mobility Analysis. Vega AR, Freeman SA, Grinstein S, Jaqaman K Biophys. J. 2018 Mar 114 5 1018-1025 Results 1-10 of 25 1 2 3 Next Last Honors & Awards Maximizing Investigator's Research Award (2016-2021) Cancer Prevention & Research Institute of Texas Scholar (2013-2017) Deborah and W. A. Tex Moncrief, Jr. Endowed Scholar in Medical Research (2013) Helen Hay Whitney Postdoctoral Fellow (2005-2008) Richard Slagle Fellow, Indiana University Bloomington (2001-2002) Valedictorian, Graduation commencement, Birzeit University (1998) Professional Associations/Affiliations American Association for the Advancement of Science (2017) American Society for Cell Biology (2004) Biophysical Society (2011)
