University of Rochester (2000), Chemistry
Graduate School
Cornell University Medical Col (2007), Molecular & Cell Biology

Research Interest

  • host-pathogen interactions
  • innate immune response to viral infection
  • viral pathogenesis and host genetic determinants
  • virus reporters (fluorescent/luminescent) and host screening technology (CRISPR, cDNA)
  • virus-host interactions; evolutionary conflicts in mammals


Featured Publications LegendFeatured Publications

A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection.
Heisler DB, Johnson KA, Ma DH, Ohlson MB, Zhang L, Tran M, Corley CD, Abrams ME, McDonald JG, Schoggins JW, Alto NM, Radhakrishnan A, Elife 2023 Jan 12
CRISPR screening reveals a dependency on ribosome recycling for efficient SARS-CoV-2 programmed ribosomal frameshifting and viral replication.
Rehfeld F, Eitson JL, Ohlson MB, Chang TC, Schoggins JW, Mendell JT, Cell Rep 2023 Jan 42 2 112076
A Multi-Omics Approach Reveals Features That Permit Robust and Widespread Regulation of IFN-Inducible Antiviral Effectors.
Göczi L, Csumita M, Horváth A, Nagy G, Póliska S, Pigni M, Thelemann C, Dániel B, Mianesaz H, Varga T, Sen K, Raghav SK, Schoggins JW, Nagy L, Acha-Orbea H, Meissner F, Reith W, Széles L, J Immunol 2022 Nov 209 10 1930-1941
Enterovirus 3C Protease Cleaves TRIM7 To Dampen Its Antiviral Activity.
Fan W, McDougal MB, Schoggins JW, J Virol 2022 Sep e0133222

Honors & Awards

  • NIH Director's Pioneer Award
  • American Lung Association Innovation Award
  • Burroughs Wellcome Investigator in Pathogenesis of Infectious Disease
  • The Welch Foundation Award
  • Clayton Foundation Scholar
  • Rita Allen Foundation Scholar
  • NIH Director's New Innovator Award
  • Seymour and Vivian Milstein Young Investigator Award
  • NIH K01 Career Development Award
  • Sidney & Joan Pestka Award for Excellence in Interferon Research

Professional Associations/Affiliations

  • American Society of Microbiology (2014)
  • American Society of Virology (2009)
  • International Cytokine and Interferon Society (2011)