Takeshi Yokoo, M.D., Ph.D., is an Associate Professor of Radiology at UT Southwestern Medical Center and a member of its Body Magnetic Resonance Imaging (MRI) Division. He also serves as Medical Director of MRI for University Hospitals and Clinics, and chief of MRI for Parkland Memorial Hospital's Department of Radiology. His clinical interests include imaging of liver cancer and chronic liver disease.

Dr. Yokoo holds a bachelor's degree in mathematics from Williams College in Williamstown, Massachusetts. He earned his doctorate in biomathematics and his medical degree at Mount Sinai School of Medicine in New York. He then completed his residency in diagnostic radiology on a five-year research track at the University of California, San Diego before obtaining advanced training in abdominal imaging and intervention through a fellowship at Massachusetts General Hospital in Boston.

A passion for research

Dr. Yokoo focuses on researching quantitative imaging techniques in order to support radiologists in objective interpretation and standardized reporting of imaging studies. He has collaborated with MRI manufacturers to develop product sequences that are now available for routine clinical imaging use. Through his extensive research and work in technological imaging advancement, along with his research on topics such as diffuse liver disease and liver cancer, Dr. Yokoo has authored or co-authored more than 50 peer-reviewed publications.  

A career marked by service

In addition to serving on numerous committees for the UTSW Radiology Department, Dr. Yokoo is an active member of several national and international professional societies, including the American College of Radiology, the Society of Abdominal Radiology, the Radiological Society of North America, the American Board of Radiology, and the International Society of Magnetic Resonance in Medicine

He is an active reviewer for the Journal of Magnetic Resonance Imaging and Magnetic Resonance in Medicine; for the latter, he has been recognized as a distinguished reviewer five timesIn addition, he has served as an ad hoc reviewer on a range of publications such as Abdominal ImagingJournal of Hematology, and European Radiology. He also served as a guest editor for a special issue of BioMed Research International focused on "Advances in MR Imaging Techniques and Applications.”


Medical School
Mount Sinai School of Medicine (2005)
North Shore-Long Island Jewish (2006), Internal Medicine
UC San Diego (2011), Diagnostic Radiology
Massachusetts General Hospital (2012), F

Research Interest

  • Diffuse Liver Disease (liver fat, iron, fibrosis)
  • Hepatocellular Carcinoma
  • Image Analysis, Signal Processing
  • Image Computation and Quantification
  • Liver Imaging
  • Magnetic Resonance Imaging and Spectroscopy


Featured Publications LegendFeatured Publications

Effect of PRESS and STEAM sequences on magnetic resonance spectroscopic liver fat quantification.
Hamilton G, Middleton MS, Bydder M, Yokoo T, Schwimmer JB, Kono Y, Patton HM, Lavine JE, Sirlin CB J Magn Reson Imaging 2009 Jul 30 1 145-52
Heritability of nonalcoholic fatty liver disease.
Schwimmer JB, Celedon MA, Lavine JE, Salem R, Campbell N, Schork NJ, Shiehmorteza M, Yokoo T, Chavez A, Middleton MS, Sirlin CB Gastroenterology 2009 May 136 5 1585-92
Nonalcoholic fatty liver disease: diagnostic and fat-grading accuracy of low-flip-angle multiecho gradient-recalled-echo MR imaging at 1.5 T.
Yokoo T, Bydder M, Hamilton G, Middleton MS, Gamst AC, Wolfson T, Hassanein T, Patton HM, Lavine JE, Schwimmer JB, Sirlin CB Radiology 2009 Apr 251 1 67-76
Fatty liver disease: MR imaging techniques for the detection and quantification of liver steatosis.
Cassidy FH, Yokoo T, Aganovic L, Hanna RF, Bydder M, Middleton MS, Hamilton G, Chavez AD, Schwimmer JB, Sirlin CB Radiographics 2009 Jan-Feb 29 1 231-60
Optimal phased-array combination for spectroscopy.
Bydder M, Hamilton G, Yokoo T, Sirlin CB Magn Reson Imaging 2008 Jul 26 6 847-50
Effects of intravenous gadolinium administration and flip angle on the assessment of liver fat signal fraction with opposed-phase and in-phase imaging.
Yokoo T, Collins JM, Hanna RF, Bydder M, Middleton MS, Sirlin CB J Magn Reson Imaging 2008 Jul 28 1 246-51
Relaxation effects in the quantification of fat using gradient echo imaging.
Bydder M, Yokoo T, Hamilton G, Middleton MS, Chavez AD, Schwimmer JB, Lavine JE, Sirlin CB Magn Reson Imaging 2008 Apr 26 3 347-59
Extraction of the average and differential dynamical response in stimulus-locked experimental data.
Sornborger A, Yokoo T, Delorme A, Sailstad C, Sirovich L J. Neurosci. Methods 2005 Feb 141 2 223-9
An optimization approach to signal extraction from noisy multivariate data.
Yokoo T, Knight BW, Sirovich L Neuroimage 2001 Dec 14 6 1309-26


Featured Books Legend Featured Books

Honors & Awards

  • RSNA Research Scholar Award
  • RSNA Roentgen Resident Research Award
  • RSNA Trainee Research Award
  • RSNA R&E Foundation Resident Research Grant
  • Honors in Mathematics, Williams College