Takeshi Yokoo, M.D., Ph.D., is an Associate Professor of Radiology at UT Southwestern Medical Center and a member of its Body Magnetic Resonance Imaging (MRI) Division. He also serves as Medical Director of MRI for University Hospitals and Clinics, and chief of MRI for Parkland Memorial Hospital's Department of Radiology. His clinical interests include imaging of liver cancer and chronic liver disease.
Dr. Yokoo holds a bachelor's degree in mathematics from Williams College in Williamstown, Massachusetts. He earned his doctorate in biomathematics and his medical degree at Mount Sinai School of Medicine in New York. He then completed his residency in diagnostic radiology on a five-year research track at the University of California, San Diego before obtaining advanced training in abdominal imaging and intervention through a fellowship at Massachusetts General Hospital in Boston.
A passion for research
Dr. Yokoo focuses on researching quantitative imaging techniques in order to support radiologists in objective interpretation and standardized reporting of imaging studies. He has collaborated with MRI manufacturers to develop product sequences that are now available for routine clinical imaging use. Through his extensive research and work in technological imaging advancement, along with his research on topics such as diffuse liver disease and liver cancer, Dr. Yokoo has authored or co-authored more than 50 peer-reviewed publications.
A career marked by service
In addition to serving on numerous committees for the UTSW Radiology Department, Dr. Yokoo is an active member of several national and international professional societies, including the American College of Radiology, the Society of Abdominal Radiology, the Radiological Society of North America, the American Board of Radiology, and the International Society of Magnetic Resonance in Medicine
He is an active reviewer for the Journal of Magnetic Resonance Imaging and Magnetic Resonance in Medicine; for the latter, he has been recognized as a distinguished reviewer five times. In addition, he has served as an ad hoc reviewer on a range of publications such as Abdominal Imaging, Journal of Hematology, and European Radiology. He also served as a guest editor for a special issue of BioMed Research International focused on "Advances in MR Imaging Techniques and Applications.”
- Medical School
- Mount Sinai School of Medicine (2005)
- North Shore-Long Island Jewish (2006), Internal Medicine
- UC San Diego (2011), Diagnostic Radiology
- Massachusetts General Hospital (2012), F
- Diffuse Liver Disease (liver fat, iron, fibrosis)
- Hepatocellular Carcinoma
- Image Analysis, Signal Processing
- Image Computation and Quantification
- Liver Imaging
- Magnetic Resonance Imaging and Spectroscopy
- Fat and iron quantification in the liver: past, present, and future.
- Yokoo T, Browning JD Top Magn Reson Imaging 2014 Apr 23 2 129-50
- Establishment of a Multidisciplinary Hepatocellular Carcinoma Clinic is Associated with Improved Clinical Outcome.
- Yopp AC, Mansour JC, Beg MS, Arenas J, Trimmer C, Reddick M, Pedrosa I, Khatri G, Yakoo T, Meyer JJ, Shaw J, Marrero JA, Singal AG Ann. Surg. Oncol. 2013 Dec
- Effect of echo-sampling strategy on the accuracy of out-of-phase and in-phase multiecho gradient-Echo MRI hepatic fat fraction estimation.
- Levin YS, Yokoo T, Wolfson T, Gamst AC, Collins J, Achmad EA, Hamilton G, Middleton MS, Loomba R, Sirlin CB J Magn Reson Imaging 2013 May
- Reproducibility of hepatic fat fraction measurement by magnetic resonance imaging.
- Mashhood A, Railkar R, Yokoo T, Levin Y, Clark L, Fox-Bosetti S, Middleton MS, Riek J, Kauh E, Dardzinski BJ, Williams D, Sirlin C, Shire NJ J Magn Reson Imaging 2012 Nov
- A multivariate, multitaper approach to detecting and estimating harmonic response in cortical optical imaging data.
- Sornborger AT, Yokoo T J. Neurosci. Methods 2012 Jan 203 1 254-63
- In vivo characterization of the liver fat ¹H MR spectrum.
- Hamilton G, Yokoo T, Bydder M, Cruite I, Schroeder ME, Sirlin CB, Middleton MS NMR Biomed 2011 Aug 24 7 784-90
- Estimation of hepatic proton-density fat fraction by using MR imaging at 3.0 T.
- Yokoo T, Shiehmorteza M, Hamilton G, Wolfson T, Schroeder ME, Middleton MS, Bydder M, Gamst AC, Kono Y, Kuo A, Patton HM, Horgan S, Lavine JE, Schwimmer JB, Sirlin CB Radiology 2011 Mar 258 3 749-59
- Constraining the initial phase in water-fat separation.
- Bydder M, Yokoo T, Yu H, Carl M, Reeder SB, Sirlin CB Magn Reson Imaging 2011 Feb 29 2 216-21
- Assessment of liver fat quantification in the presence of iron.
- Bydder M, Shiehmorteza M, Yokoo T, Sugay S, Middleton MS, Girard O, Schroeder ME, Wolfson T, Gamst A, Sirlin C Magn Reson Imaging 2010 Jul 28 6 767-76
- A quantitative approach to sequence and image weighting.
- Yokoo T, Bae WC, Hamilton G, Karimi A, Borgstede JP, Bowen BC, Sirlin CB, Chung CB, Crues JV, Bradley WG, Bydder GM J Comput Assist Tomogr 2010 May-Jun 34 3 317-31
Ch. 65: Fatty Liver. In Abdominal Imaging
Sirlin, CB, Mazhar S, Faria S, Yokoo T (2009). Maryland Heights, MO, Saunders Elsevier Publishing
Ch. 9: Imaging of NAFLD. In Non-Alcoholic Fatty Liver Disease: A Practical Guide
Yokoo T, Tang A, and Sirlin, CB. (2012). Chichester, UK, Wiley-Blackwell Publishing
Honors & Awards
- RSNA Research Scholar Award
- RSNA Roentgen Resident Research Award
- RSNA Trainee Research Award
- RSNA R&E Foundation Resident Research Grant
- Honors in Mathematics, Williams College