Takeshi Yokoo, M.D., Ph.D., is an Associate Professor of Radiology at UT Southwestern Medical Center and a member of its Body Magnetic Resonance Imaging (MRI) Division. He also serves as Medical Director of MRI for University Hospitals and Clinics, and chief of MRI for Parkland Memorial Hospital's Department of Radiology. His clinical interests include imaging of liver cancer and chronic liver disease.
Dr. Yokoo holds a bachelor's degree in mathematics from Williams College in Williamstown, Massachusetts. He earned his doctorate in biomathematics and his medical degree at Mount Sinai School of Medicine in New York. He then completed his residency in diagnostic radiology on a five-year research track at the University of California, San Diego before obtaining advanced training in abdominal imaging and intervention through a fellowship at Massachusetts General Hospital in Boston.
A passion for research
Dr. Yokoo focuses on researching quantitative imaging techniques in order to support radiologists in objective interpretation and standardized reporting of imaging studies. He has collaborated with MRI manufacturers to develop product sequences that are now available for routine clinical imaging use. Through his extensive research and work in technological imaging advancement, along with his research on topics such as diffuse liver disease and liver cancer, Dr. Yokoo has authored or co-authored more than 50 peer-reviewed publications.
A career marked by service
In addition to serving on numerous committees for the UTSW Radiology Department, Dr. Yokoo is an active member of several national and international professional societies, including the American College of Radiology, the Society of Abdominal Radiology, the Radiological Society of North America, the American Board of Radiology, and the International Society of Magnetic Resonance in Medicine
He is an active reviewer for the Journal of Magnetic Resonance Imaging and Magnetic Resonance in Medicine; for the latter, he has been recognized as a distinguished reviewer five times. In addition, he has served as an ad hoc reviewer on a range of publications such as Abdominal Imaging, Journal of Hematology, and European Radiology. He also served as a guest editor for a special issue of BioMed Research International focused on "Advances in MR Imaging Techniques and Applications.”
- Medical School
- Mount Sinai School of Medicine (2005)
- North Shore-Long Island Jewish (2006), Internal Medicine
- UC San Diego (2011), Diagnostic Radiology
- Massachusetts General Hospital (2012), F
- Diffuse Liver Disease (liver fat, iron, fibrosis)
- Hepatocellular Carcinoma
- Image Analysis, Signal Processing
- Image Computation and Quantification
- Liver Imaging
- Magnetic Resonance Imaging and Spectroscopy
- Optimization of breathing instructions and timing of late arterial phase acquisition on gadobutrol-enhanced MRI of the liver.
- Pinho DF, Lev-Cohain N, Awdeh H, Xi Y, Khatri G, Yokoo T, Pedrosa I Clin Imaging 2016 Sep 40 6 1274-1279
- Multisite, multivendor validation of the accuracy and reproducibility of proton-density fat-fraction quantification at 1.5T and 3T using a fat-water phantom.
- Hernando D, Sharma SD, Aliyari Ghasabeh M, Alvis BD, Arora SS, Hamilton G, Pan L, Shaffer JM, Sofue K, Szeverenyi NM, Welch EB, Yuan Q, Bashir MR, Kamel IR, Rice MJ, Sirlin CB, Yokoo T, Reeder SB Magn Reson Med 2016 Apr
- Effect of steatosis on liver signal and enhancement on multiphasic contrast-enhanced magnetic resonance imaging.
- Pirasteh A, Clark HR, Sorra EA, Pedrosa I, Yokoo T Abdom Radiol (NY) 2016 Apr
- Radiation-Induced Liver Injury Mimicking Metastatic Disease in a Patient With Esophageal Cancer: Correlation of Positron Emission Tomography/Computed Tomography With Magnetic Resonance Imaging and Literature Review.
- Rabe TM, Yokoo T, Meyer J, Kernstine KH, Wang D, Khatri G J Comput Assist Tomogr 2016 Mar
- Mechanisms of Action of Liraglutide in Patients with Type 2 Diabetes Treated with High Dose Insulin.
- Vanderheiden A, Harrison LB, Warshauer JT, Adams-Huet B, Li X, Yuan Q, Hulsey K, Dimitrov I, Yokoo T, Jaster AW, Pinho DF, Pedrosa I, Lenkinski RE, Pop LM, Lingvay I J. Clin. Endocrinol. Metab. 2016 Feb jc20153906
- Quantitative Imaging Biomarkers of NAFLD.
- Kinner S, Reeder SB, Yokoo T Dig. Dis. Sci. 2016 Feb
- Feasibility of and agreement between MR imaging and spectroscopic estimation of hepatic proton density fat fraction in children with known or suspected nonalcoholic fatty liver disease.
- Achmad E, Yokoo T, Hamilton G, Heba ER, Hooker JC, Changchien C, Schroeder M, Wolfson T, Gamst A, Schwimmer JB, Lavine JE, Sirlin CB, Middleton MS Abdom Imaging 2015 Jul
- A Phase I Dose-Escalation Trial of Single-Fraction Stereotactic Radiation Therapy for Liver Metastases.
- Meyer JJ, Foster RD, Lev-Cohain N, Yokoo T, Dong Y, Schwarz RE, Rule W, Tian J, Xie Y, Hannan R, Nedzi L, Solberg T, Timmerman R Ann. Surg. Oncol. 2015 May
- Evaluation of Liver Fibrosis Using Texture Analysis on Combined-Contrast-Enhanced Magnetic Resonance Images at 3.0T.
- Yokoo T, Wolfson T, Iwaisako K, Peterson MR, Mani H, Goodman Z, Changchien C, Middleton MS, Gamst AC, Mazhar SM, Kono Y, Ho SB, Sirlin CB Biomed Res Int 2015 2015 387653
- Advances in MRI Techniques and Applications.
- Dong Z, Andrews T, Xie C, Yokoo T Biomed Res Int 2015 2015 139043
Ch. 65: Fatty Liver. In Abdominal Imaging
Sirlin, CB, Mazhar S, Faria S, Yokoo T (2009). Maryland Heights, MO, Saunders Elsevier Publishing
Ch. 9: Imaging of NAFLD. In Non-Alcoholic Fatty Liver Disease: A Practical Guide
Yokoo T, Tang A, and Sirlin, CB. (2012). Chichester, UK, Wiley-Blackwell Publishing
Honors & Awards
- RSNA Research Scholar Award
- RSNA Roentgen Resident Research Award
- RSNA Trainee Research Award
- RSNA R&E Foundation Resident Research Grant
- Honors in Mathematics, Williams College