Takeshi Yokoo, M.D., Ph.D.

Takeshi Yokoo, M.D., Ph.D., is an Associate Professor of Radiology at UT Southwestern Medical Center and a member of its Body Magnetic Resonance Imaging (MRI) Division. He also serves as Medical Director of MRI for University Hospitals and Clinics, and chief of MRI for Parkland Memorial Hospital's Department of Radiology. His clinical interests include imaging of liver cancer and chronic liver disease.

Dr. Yokoo holds a bachelor's degree in mathematics from Williams College in Williamstown, Massachusetts. He earned his doctorate in biomathematics and his medical degree at Mount Sinai School of Medicine in New York. He then completed his residency in diagnostic radiology on a five-year research track at the University of California, San Diego before obtaining advanced training in abdominal imaging and intervention through a fellowship at Massachusetts General Hospital in Boston.

A passion for research

Dr. Yokoo focuses on researching quantitative imaging techniques in order to support radiologists in objective interpretation and standardized reporting of imaging studies. He has collaborated with MRI manufacturers to develop product sequences that are now available for routine clinical imaging use. Through his extensive research and work in technological imaging advancement, along with his research on topics such as diffuse liver disease and liver cancer, Dr. Yokoo has authored or co-authored more than 50 peer-reviewed publications.  

A career marked by service

In addition to serving on numerous committees for the UTSW Radiology Department, Dr. Yokoo is an active member of several national and international professional societies, including the American College of Radiology, the Society of Abdominal Radiology, the Radiological Society of North America, the American Board of Radiology, and the International Society of Magnetic Resonance in Medicine

He is an active reviewer for the Journal of Magnetic Resonance Imaging and Magnetic Resonance in Medicine; for the latter, he has been recognized as a distinguished reviewer five times. In addition, he has served as an ad hoc reviewer on a range of publications such as Abdominal Imaging, Journal of Hematology, and European Radiology. He also served as a guest editor for a special issue of BioMed Research International focused on "Advances in MR Imaging Techniques and Applications.”

Medical School

Mount Sinai School of Medicine (2005)

Internship

North Shore-Long Island Jewish (2006), Internal Medicine

Residency

UC San Diego (2011), Diagnostic Radiology

Fellowship

Massachusetts General Hospital (2012), F

• Diffuse Liver Disease (liver fat, iron, fibrosis)
• Hepatocellular Carcinoma
• Image Analysis, Signal Processing
• Image Computation and Quantification
• Liver Imaging
• Magnetic Resonance Imaging and Spectroscopy

Featured Publications

Abbreviated-protocol screening MRI vs. complete-protocol diagnostic MRI for detection of hepatocellular carcinoma in patients with cirrhosis: An equivalence study using LI-RADS v2018.

Khatri G, Pedrosa I, Ananthakrishnan L, de Leon AD, Fetzer DT, Leyendecker J, Singal AG, Xi Y, Yopp A, Yokoo T, J Magn Reson Imaging 2020 Feb 51 2 415-425

Linearity, Bias, and Precision of Hepatic Proton Density Fat Fraction Measurements by Using MR Imaging: A Meta-Analysis.

Yokoo T, Serai SD, Pirasteh A, Bashir MR, Hamilton G, Hernando D, Hu HH, Hetterich H, Kühn JP, Kukuk GM, Loomba R, Middleton MS, Obuchowski NA, Song JS, Tang A, Wu X, Reeder SB, Sirlin CB Radiology 2017 Sep 170550

Quantification of renal steatosis in type II diabetes mellitus using dixon-based MRI.

Yokoo T, Clark HR, Pedrosa I, Yuan Q, Dimitrov I, Zhang Y, Lingvay I, Beg MS, Bobulescu IA J Magn Reson Imaging 2016 Mar

Quantitative R2 * MRI of the liver with rician noise models for evaluation of hepatic iron overload: Simulation, phantom, and early clinical experience.

Yokoo T, Yuan Q, Sénégas J, Wiethoff AJ, Pedrosa I J Magn Reson Imaging 2015 May

Assessment of hepatocellular carcinoma treatment response with LI-RADS: a pictorial review.

Voizard N, Cerny M, Assad A, Billiard JS, Olivié D, Perreault P, Kielar A, Do RKG, Yokoo T, Sirlin CB, Tang A, Insights Imaging 2019 Dec 10 1 121

Magnetic resonance imaging of obesity and metabolic disorders: Summary from the 2019 ISMRM Workshop.

Hu HH, Branca RT, Hernando D, Karampinos DC, Machann J, McKenzie CA, Wu HH, Yokoo T, Velan SS, Magn Reson Med 2019 Nov

Prevalence and clinical significance of discordant LI-RADS^® observations on multiphase contrast-enhanced MRI in patients with cirrhosis.

Yokoo T, Singal AG, Diaz de Leon A, Ananthakrishnan L, Fetzer DT, Pedrosa I, Khatri G, Abdom Radiol (NY) 2019 Jul

Pelvic muscle size and myosteatosis: Relationship with age, gender, and obesity.

Pacicco T, Ratner S, Xi Y, Yokoo T, Fetzer D, Oz OK, Rubin CD, Chhabra A, Indian J Radiol Imaging 2019 Apr-Jun 29 2 155-162

Low-to-high b value DWI ratio approaches in multiparametric MRI of the prostate: feasibility, optimal combination of b values, and comparison with ADC maps for the visual presentation of prostate cancer.

Xi Y, Liu A, Olumba F, Lawson P, Costa DN, Yuan Q, Khatri G, Yokoo T, Pedrosa I, Lenkinski RE Quant Imaging Med Surg 2018 Jul 8 6 557-567

MR relaxometry for estimation of liver iron concentration.

Pirasteh A, Yuan Q, Hernando D, Reeder SB, Pedrosa I, Yokoo T Magn Reson Med 2018 May

 Featured Books

Ch. 65: Fatty Liver. In Abdominal Imaging

Sirlin, CB, Mazhar S, Faria S, Yokoo T (2009). Maryland Heights, MO, Saunders Elsevier Publishing

Ch. 9: Imaging of NAFLD. In Non-Alcoholic Fatty Liver Disease: A Practical Guide

Yokoo T, Tang A, and Sirlin, CB. (2012). Chichester, UK, Wiley-Blackwell Publishing

• RSNA Research Scholar Award
  (2016)
• RSNA Roentgen Resident Research Award
  (2011)
• RSNA Trainee Research Award
  (2009)
• RSNA R&E Foundation Resident Research Grant
  (2007)
• Honors in Mathematics, Williams College
  (1996)