Education: National Taiwan University, Taipei, Taiwan; BS, Plant Pathology; National Yang-Ming Medical School, Taipei, Taiwan; MS, Microbiology and Immunology; University of Wisconsin-Madison, Madison, Wisconsin, PhD, Human Cancer Biology; University of Texas, M.D. Anderson Cancer Center, Houston, Texas, Research Fellow.

Dr. Hsieh is currently a Professor and Director of Jean H. and John T. Walter, Jr., Center for Research in Urologic Oncology in the Department of Urology at UT Southwestern. Dr. Hsieh has many years experience in studying tumor biology and cancer progression of urogenital cancers, particularly, prostate, Kidney and bladder cancers. Currently, his research focuses on translational research with two main topics: one is to identify signal defects leading to androgen-independent prostate cancer progression and cancer metastases of bladder and kidney cancers; the other is to develop cancer-specific trageting nanomedicine with both imaging and therapeutic capbility. Dr. Hsieh has six nationally funded research grants on these subjects. He is collaborating with Urologists and Medical Oncologists for future clinical trials.


Graduate School
Unlisted - International Colle
Graduate School
Univ. of Wisconsin-Madison (1989)

Research Interest

  • experiemtnal therapy
  • nanomedicine
  • Prostate cancer stem cell
  • Signal network defects in urologic cancers


Featured Publications LegendFeatured Publications

The mechanism of DAB2IP in chemo-resistance of prostate cancer cells.
Wu K, Xie D, Zou Y, Zhang T, Pong RC, Xiao G, Fazli L, Gleave ME, He D, Boothman DA, Hsieh JT Clin. Cancer Res. 2013 Jul
Peptidomimetic targeting of critical androgen receptor-coregulator interactions in prostate cancer.
Ravindranathan P, Lee TK, Yang L, Centenera MM, Butler L, Tilley WD, Hsieh JT, Ahn JM, Raj GV Nat Commun 2013 May 4 1923
The role of DAB2IP in androgen receptor activation during prostate cancer progression.
Wu K, Liu J, Tseng SF, Gore C, Ning Z, Sharifi N, Fazli L, Gleave M, Kapur P, Xiao G, Sun X, Oz OK, Min W, Alexandrakis G, Yang CR, Hsieh CL, Wu HC, He D, Xie D, Hsieh JT Oncogene 2013 Apr


Featured Books Legend Featured Books

Honors & Awards

  • Visiting Professor
    Xi'an Jiaotong University (2012)
  • Dr. John McConnell Distinguished Chair in Prostate Cancer Research
  • Visiting Professor
    The Prostate Center at Vancouver General Hospital (2001)
  • SBUR/Merck Young Investigator Award

Professional Associations/Affiliations

  • American Association for Cancer Research
  • American Urological Association
  • Phi Tau Phi Scholastic Honor Society
  • Society of Basic Urologic Research
  • Society of Chinese Bioscientists in America