Dr. Gupta received both his B.A. in Biochemistry and Ph.D. in Pharmacology from the University of Pennsylvania.  His doctoral work focused on the transcriptional mechanisms controlling the function and expansion of pancreatic beta cells.  He then moved to the Dana-Farber Cancer Institute in Boston, MA where he trained as a postdoctoral fellow studying the transcriptional mechanisms governing adipocyte specification and differentiation.  Dr. Gupta joined the Touchstone Diabetes Center in 2012. The Gupta laboratory focuses on the molecular and developmental mechanisms controlling adipose tissue development and expansion in obesity. 


University of Pennsylvania (2001), Biochemistry
Graduate School
University of Pennsylvania (2006), Pharmacology

Research Interest

  • Adipocyte Development
  • Cell Differentiation
  • Obesity
  • Transcriptional Regulation


Featured Publications LegendFeatured Publications

Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase.
Ye R, Wang QA, Tao C, Vishvanath L, Shao M, McDonald JG, Gupta RK, Scherer PE Mol Metab 2015 Nov 4 11 771-8
Activation of natriuretic peptides and the sympathetic nervous system following Roux-en-Y gastric bypass is associated with gonadal adipose tissues browning.
Neinast MD, Frank AP, Zechner JF, Li Q, Vishvanath L, Palmer BF, Aguirre V, Gupta RK, Clegg DJ Mol Metab 2015 May 4 5 427-36
CREB mediates the insulinotropic and anti-apoptotic effects of GLP-1 signaling in adult mouse ß-cells.
Shin S, Le Lay J, Everett LJ, Gupta R, Rafiq K, Kaestner KH Mol Metab 2014 Nov 3 8 803-12

Honors & Awards

  • The Hartwell Foundation
    2016 Individual Biomedical Research Award (2017)
  • Grossman Award for Excellence in Diabetes Research
  • Searle Scholar
  • NIH Mentor-based Career Development Award (K01)
  • Ruth L. Kirschstein National Research Service Award (NRSA)