Biography

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Dr. Jose Torrealba completed his MD in 1994 from the Central University of Venezuela. He then did a post-doctoral fellowship in molecular biology at the University of Wisconsin, in Madison, Wisconsin and obtained his degree in Anatomic and Clinical Pathology from the Univeristy of Wisconsin as well in 2003. He especialized in immunopathology of transplantation at the University of Toronto, Canada in 2005. He held a job as Assistant Professor of Pathology at the University of Wisconsin until 2012, and since then is the Drs. George and Anne Race Distinguished Professor of Pathology at the Department of Pathology, UTSW Medical center in Dallas, Texas. Areas of experise: Thoracic Pathology, Renal Pathology and Transplant Pathology

Education

Medical School
Universidad Central De Venezuela-Hospital Universitario (1994)
Fellowship
University of Wisconsin Hospital and Clinics (1999), Molecular Cardiology
Residency
University of Wisconsin Hospital and Clinics (2003), Anatomic & Clinical Pathology
Fellowship
University of Toronto, Canada (2005), Immunology

Research Interest

  • Chronic Kidney Disease
  • Lung cancer morphology and metabolic
  • Solid Organ Transplant Immunopathology

Publications

Featured Publications LegendFeatured Publications

Guidelines for the management of a brain death donor in the rhesus macaque: A translational transplant model.
Zens TJ, Danobeitia JS, Chlebeck PJ, Zitur LJ, Odorico S, Brunner K, Coonen J, Capuano S, D'Alessandro AM, Matkowskyj K, Zhong W, Torrealba J, Fernandez L PLoS ONE 2017 12 9 e0182552
Telomere-related lung fibrosis is diagnostically heterogeneous but uniformly progressive.
Newton CA, Batra K, Torrealba J, Kozlitina J, Glazer CS, Aravena C, Meyer K, Raghu G, Collard HR, Garcia CK Eur. Respir. J. 2016 Aug
Pleuroparenchymal fibroelastosis: a pattern of chronic lung injury.
Rosenbaum JN, Butt YM, Johnson KA, Meyer K, Batra K, Kanne JP, Torrealba JR Hum. Pathol. 2015 Jan 46 1 137-46
Guidelines for the diagnosis of antibody-mediated rejection in pancreas allografts-updated Banff grading schema.
Drachenberg CB, Torrealba JR, Nankivell BJ, Rangel EB, Bajema IM, Kim DU, Arend L, Bracamonte ER, Bromberg JS, Bruijn JA, Cantarovich D, Chapman JR, Farris AB, Gaber L, Goldberg JC, Haririan A, Honsová E, Iskandar SS, Klassen DK, Kraus E, Lower F, Odorico J, Olson JL, Mittalhenkle A, Munivenkatappa R, Paraskevas S, Papadimitriou JC, Randhawa P, Reinholt FP, Renaudin K, Revelo P, Ruiz P, Samaniego MD, Shapiro R, Stratta RJ, Sutherland DE, Troxell ML, Voska L, Seshan SV, Racusen LC, Bartlett ST Am. J. Transplant. 2011 Sep 11 9 1792-802
Antibody-mediated rejection of the pancreas allograft.
Torrealba JR, Odorico J Transplantation 2009 Jul 88 2 292-3
C4d-positive interacinar capillaries correlates with donor-specific antibody-mediated rejection in pancreas allografts.
Torrealba JR, Samaniego M, Pascual J, Becker Y, Pirsch J, Sollinger H, Odorico J Transplantation 2008 Dec 86 12 1849-56
Human CD4+CD25low adaptive T regulatory cells suppress delayed-type hypersensitivity during transplant tolerance.
Xu Q, Lee J, Jankowska-Gan E, Schultz J, Roenneburg DA, Roennburg DA, Haynes LD, Kusaka S, Sollinger HW, Knechtle SJ, VanBuskirk AM, Torrealba JR, Burlingham WJ J. Immunol. 2007 Mar 178 6 3983-95
Selenium-binding protein-1 in smooth muscle cells is downregulated in a rhesus monkey model of chronic allograft nephropathy.
Torrealba JR, Colburn M, Golner S, Chang Z, Scheunemann T, Fechner JH, Roenneburg D, Hu H, Alam T, Kim HT, Kanmaz T, Oberley T, Knechtle SJ, Hamawy MM Am. J. Transplant. 2005 Jan 5 1 58-67
Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
Torrealba JR, Katayama M, Fechner JH, Jankowska-Gan E, Kusaka S, Xu Q, Schultz JM, Oberley TD, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ J. Immunol. 2004 May 172 9 5753-64
Immunotoxin-treated rhesus monkeys: a model for renal allograft chronic rejection.
Torrealba JR, Fernandez LA, Kanmaz T, Oberley TD, Schultz JM, Brunner KG, Peters D, Fechner JH, Dong Y, Hu H, Hamawy MM, Knechtle SJ Transplantation 2003 Aug 76 3 524-30

Books

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Honors & Awards

  • Society of Cardiovascular Pathology Young Investigator’s Award, USCAP
    Trainee platform presentation of CD68/CD31 Immunohistochemistry Double Stain Demonstrates Increased Accuracy in Diagnosing Antibody-Mediated Rejection in Cardiac Transplant Patients (2018)
  • Poster of Distinction, American Transplant Congress
    “Banff 2013 Classification of Renal Allograft Pathology Is Superior to Banff 2007 in Detecting and Managing Milder and Earlier Cases of Antibody-Mediated Rejection”. (2017)
  • Poster of Distinction, World Transplant Congress.
    “Histopathology of Long Term Tolerant Kidney Allografts in Rhesus monkeys (2014)
  • Drs. George and Anne Race Distinguished Professor of Pathology, University of Texas Southwestern Medical Center
    Endowment Fund (2012)
  • Gold Microscope Award in Anatomic Pathology.
    In recognition of Residency Education, Department of Laboratory Medicine and Pathology, University of Wisconsin (2010)
  • Sheard Sandford Pathology Resident Award, 2003 American Society of Clinical Pathology Annual Meeting
    Research article “TGF+ 1 mediated immune regulation of renal transplants correlates with infiltrating TGF+ T regulatory cells in the allografts”. Diploma and Leica Microscope DMLS. (2003)
  • Sheard Sandford Pathology Resident Award, 2002 American Society of Clinical Pathology/College of American Pathology Annual Meeting
    Research article “Piceatannol is associated with increased survival and reduced mononuclear cells in renal allografts”. Diploma and Leica Microscope DMLS. (2002)
  • Award: “Dr. Lorenzo Campins y Ballester”
    Academic Excellence, Faculty of Medicine, Central University of Venezuela. (1994)
  • Magna Cum Laude
    Achieving the highest average grade in the corresponding class of 1994, Faculty of Medicine, Central University of Venezuela. (1994)

Professional Associations/Affiliations

  • United States and Canadian Association of Pathology (2016)
  • Royal College of Physicians of Canada (RCPC) (2006)
  • American Society of Transplantation (2003)
  • College of American Pathology (2001)