Biography

Dr. Udayakumar graduated from Medical College of Georgia, (Georgia Health Sciences University) Augusta GA in 2005 with a PhD in Molecular Medicine with emphasis on biochemical signaling in DNA damage and repair under the mentorship of Dr. William S. Dynan. She then completed her post-doctoral trainings at Beth Israel Deaconess Medical Center, Dept of Pathology and Massachusetts General Hospital, Harvard Medical School, Dept of Dermatology on Tumor Vascular Biology, and Melanoma tumorigenesis. In 2011 she held an Instructor appointment at MGH, Harvard Medical School with research focused on Genetic determinants of UV induced skin cancers. In 2012, she joined University of Texas Southwestern Medical Center as an Instructor in the Department of Radiation Oncology. Since 2015, she has been appointed as Assistant Professor in the Department of Radiology at University of Texas Southwestern Medical Center. Her research interest is on Radiogenomics with a special focus on identifying imaging measures extracted from quantitative MRI parameters as a non invasive tool to better predict biological characteristics in clear cell renal cell carcinoma.

 

Education
Undergraduate
Anna University - India (2000), Biotechnology
Graduate School
Augusta University (2005), Molecular Medicine

Publications

Featured Publications LegendFeatured Publications

Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI.
Zhang Y, Udayakumar D, Cai L, Hu Z, Kapur P, Kho EY, Pavía-Jiménez A, Fulkerson M, de Leon AD, Yuan Q, Dimitrov IE, Yokoo T, Ye J, Mitsche MA, Kim H, McDonald JG, Xi Y, Madhuranthakam AJ, Dwivedi DK, Lenkinski RE, Cadeddu JA, Margulis V, Brugarolas J, DeBerardinis RJ, Pedrosa I JCI Insight 2017 Aug 2 15
Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine.
Harshbarger W, Gondi S, Ficarro SB, Hunter J, Udayakumar D, Gurbani D, Singer W, Liu Y, Li L, Marto JA, Westover KD J. Biol. Chem. 2016 Nov
Characterization of DNA binding and pairing activities associated with the native SFPQ·NONO DNA repair protein complex.
Udayakumar D, Dynan WS Biochem. Biophys. Res. Commun. 2015 Aug 463 4 473-8
Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs.
Pandita RK, Chow TT, Udayakumar D, Bain AL, Cubeddu L, Hunt CR, Shi W, Horikoshi N, Zhao Y, Wright WE, Khanna KK, Shay JW, Pandita TK Cancer Res. 2015 Mar 75 5 858-69
Detecting ATM-dependent chromatin modification in DNA damage response.
Udayakumar D, Horikoshi N, Mishra L, Hunt C, Pandita TK Methods Mol. Biol. 2015 1288 317-36
Melanocytes Are Selectively Vulnerable to UVA-Mediated Bystander Oxidative Signaling.
Redmond RW, Rajadurai A, Udayakumar D, Sviderskaya EV, Tsao H J. Invest. Dermatol. 2013 Nov
EphA2 is a critical oncogene in melanoma.
Udayakumar D, Zhang G, Ji Z, Njauw CN, Mroz P, Tsao H Oncogene 2011 Dec 30 50 4921-9
Genetic determinants of cutaneous melanoma predisposition.
Udayakumar D, Mahato B, Gabree M, Tsao H Semin Cutan Med Surg 2010 Sep 29 3 190-5
Dynamic gene expression analysis links melanocyte growth arrest with nevogenesis.
Yang G, Thieu K, Tsai KY, Piris A, Udayakumar D, Njauw CN, Ramoni MF, Tsao H Cancer Res. 2009 Dec 69 23 9029-37
Identification of the polypyrimidine tract binding protein-associated splicing factor.p54(nrb) complex as a candidate DNA double-strand break rejoining factor.
Bladen CL, Udayakumar D, Takeda Y, Dynan WS J. Biol. Chem. 2005 Feb 280 7 5205-10