Ho Yee Joyce Fung, Ph.D.

Assistant Professor

School: Medical School
Department: Biophysics
Graduate Programs: Molecular Biophysics

Research Interest

Cryogenic electron microscopy
Fluorescence spectroscopy
Micro/3D electron diffraction

Publications

Nap1 and Kap114 co-chaperone H2A-H2B and facilitate targeted histone release in the nucleus: Fung HY, Jiou J, Niesman AB, Bernardes NE, Chook YM The Journal of cell biology 2025 Jan 224
Molecular basis of RanGTP-activated release of Histones H2A-H2B from Importin-9: Shaffer JM, Jiou J, Tripathi K, Olaluwoye OS, Fung HY, Chook YM, D'Arcy S Structure 2023 Aug 31 903-911.e3
A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders: Gonzalez A, Kim HJ, Freibaum BD, Fung HY, Brautigam CA, Taylor JP, Chook YM Structure 2023 Aug 31 924-934.e4
Structure of IMPORTIN-4 bound to the H3–H4–ASF1 histone–histone chaperone complex: Bernardes NE, Fung HY, Li Y, Chen Z, Chook YM Proceedings of the National Academy of Sciences of the United States of America 2022 Sep 119
Karyopherin-mediated nucleocytoplasmic transport: Wing CE, Fung HY, Chook YM Nature Reviews Molecular Cell Biology 2022 May 23 307-328
Binding Affinity Measurement of Nuclear Export Signal Peptides to Their Exporter CRM1: Fung HY, Chook YM 2022 245-256
Crystallization of Nuclear Export Signals or Small-Molecule Inhibitors Bound to Nuclear Exporter CRM1: Fung HY, Chook YM 2022 285-297
An update to the CRM1 cargo/NES database NESdb: Fung HY, Niesman A, Chook YM Molecular biology of the cell 2021 Mar 32 467-469
Structural Characterization of Tau in Fuzzy Tau:Tubulin Complexes: Fung HY, McKibben KM, Ramirez J, Gupta K, Rhoades E Structure 2020 Mar 28 378-384.e4
Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization: Pinarbasi ES, Caǧatay T, Fung HY, Li YC, Chook YM, Thomas PJ Scientific reports 2018 Dec 8