Shani Shastri, M.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of the Division of Nephrology.

Originally from India, Dr. Shastri completed her medical education at K.J. Somaiya Medical Center in Mumbai, India. She holds a master's degree in public health from the University of Loma Linda in California.  She completed internal medicine residency training at the University of Massachusetts and completed advanced training through a fellowship in nephrology at Tufts Medical Center.  During her fellowship, she also earned a master’s degree in clinical research with a focus on epidemiology and outcomes. 

Dr. Shastri's research interests include investigations of aging and kidney disease and cardiovascular disease coupled with kidney disease. 


Medical School
K.J. Somaiya Medical College, India (1997)
Medical School
Loma Linda University (1999)
Frankford Hospital of Philadelphia (2005), Transitional Year
University of Massachusetts Medical Center (2008), Internal Medicine
Medical School
Sackler School of Graduate Biomedical Sciences (2010), Research
Tufts Medical Center (2011), Nephrology

Research Interest

  • Aging
  • Cardiovascular Outcomes in Kidney Disease
  • Epidemiology and Outcomes in Chronic Kidney Disease
  • Epidemiology and Outcomes in Hemodialysis


Featured Publications LegendFeatured Publications

Obesity, inflammatory and thrombotic markers, and major clinical outcomes in critically ill patients with COVID-19 in the US.
Friedman AN, Guirguis J, Kapoor R, Gupta S, Leaf DE, Timsina LR, Obesity (Silver Spring) 2021 Jun
Characteristics and Outcomes of Individuals With Pre-existing Kidney Disease and COVID-19 Admitted to Intensive Care Units in the United States.
Flythe JE, Assimon MM, Tugman MJ, Chang EH, Gupta S, Shah J, Sosa MA, Renaghan AD, Melamed ML, Wilson FP, Neyra JA, Rashidi A, Boyle SM, Anand S, Christov M, Thomas LF, Edmonston D, Leaf DE, Am J Kidney Dis 2021 02 77 2 190-203.e1
Extracorporeal membrane oxygenation in patients with severe respiratory failure from COVID-19.
Shaefi S, Brenner SK, Gupta S, O'Gara BP, Krajewski ML, Charytan DM, Chaudhry S, Mirza SH, Peev V, Anderson M, Bansal A, Hayek SS, Srivastava A, Mathews KS, Johns TS, Leonberg-Yoo A, Green A, Arunthamakun J, Wille KM, Shaukat T, Singh H, Admon AJ, Semler MW, Hernán MA, Mueller AL, Wang W, Leaf DE, Intensive Care Med 2021 02 47 2 208-221
Idiopathic hypokalemia in lupus nephritis - A newly recognized entity
Adomako EA , Bilal S, Liu Y, Malik A, Van Buren PN, Shastri S and Sambandam KK Kidney360 2021
Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19.
Gupta S, Wang W, Hayek SS, Chan L, Mathews KS, Melamed ML, Brenner SK, Leonberg-Yoo A, Schenck EJ, Radbel J, Reiser J, Bansal A, Srivastava A, Zhou Y, Finkel D, Green A, Mallappallil M, Faugno AJ, Zhang J, Velez JCQ, Shaefi S, Parikh CR, Charytan DM, Athavale AM, Friedman AN, Redfern RE, Short SAP, Correa S, Pokharel KK, Admon AJ, Donnelly JP, Gershengorn HB, Douin DJ, Semler MW, Hernán MA, Leaf DE, JAMA Intern Med 2021 01 181 1 41-51
Outcomes of critically ill solid organ transplant patients with COVID-19 in the United States.
Molnar MZ, Bhalla A, Azhar A, Tsujita M, Talwar M, Balaraman V, Sodhi A, Kadaria D, Eason JD, Hayek SS, Coca SG, Shaefi S, Neyra JA, Gupta S, Leaf DE, Kovesdy CP, Am J Transplant 2020 11 20 11 3061-3071


Featured Books Legend Featured Books

Honors & Awards

  • John Insall Award
    Knee Society (2002)
  • Albert E. Barnett Health Administration Scholarship
  • Jan Hirsh Health Administration Scholarship

Professional Associations/Affiliations

  • American Society of Nephrology (2008)